Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kelly M Blaine"'
Autor:
Ayodeji Adegunsoye, Cara Hrusch, Catherine Bonham, Mohammad R Jaffrey, Kelly M Blaine, Meghan Sullivan, Matthew M Churpek, Mary E Strek, Imre Noth, Anne I Sperling
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Rationale: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal lung disease. While it has been suggested that T cells may contribute to IPF pathogenesis, these studies have focused primarily on T cells outside of the pulmonary interstitium. T
Externí odkaz:
https://doaj.org/article/2c17d42e83944e5580b3301f0a55766d
Autor:
Judy L Cannon, Francois Asperti-Boursin, Kenneth A Letendre, Ivy K Brown, Katy E Korzekwa, Kelly M Blaine, Sreenivasa R Oruganti, Anne I Sperling, Melanie E Moses
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78940 (2013)
Cell motility is a fundamental process crucial for function in many cell types, including T cells. T cell motility is critical for T cell-mediated immune responses, including initiation, activation, and effector function. While many extracellular rec
Externí odkaz:
https://doaj.org/article/5c84207b2711443c95df818a41680a26
Autor:
Ivy Aneas, Donna C. Decker, Chanie L. Howard, Débora R. Sobreira, Noboru J. Sakabe, Kelly M. Blaine, Michelle M. Stein, Cara L. Hrusch, Lindsey E. Montefiori, Juan Tena, Kevin M. Magnaye, Selene M. Clay, James E. Gern, Daniel J. Jackson, Matthew C. Altman, Edward T. Naureckas, Douglas K. Hogarth, Steven R. White, Jose Luis Gomez-Skarmeta, Nathan Schoetler, Carole Ober, Anne I. Sperling, Marcelo A. Nóbrega
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Susceptibility to asthma and severity of symptoms are regulated by a number of different genomic regions. Here the authors characterise a 5kb regulatory region and demonstrate genetic and topological regulation of IL33 and association with disease in
Externí odkaz:
https://doaj.org/article/91de69f13ca849d4bde27470e200f0b0
Autor:
Young me Yoon, Tania E. Velez, Vaibhav Upadhyay, Sara E. Vazquez, Cathryn T. Lee, Kavitha C. Selvan, Christopher S. Law, Kelly M. Blaine, Maile K. Hollinger, Donna C. Decker, Marcus R. Clark, Mary E. Strek, Robert D. Guzy, Ayodeji Adegunsoye, Imre Noth, Paul J. Wolters, Mark Anderson, Joseph L. DeRisi, Anthony K. Shum, Anne I. Sperling
SummaryInterstitial lung diseases (ILD) are heterogeneous conditions that may lead to progressive fibrosis and death of affected individuals. Despite diversity in clinical manifestations, enlargement of lung-associated lymph nodes (LLN) in fibrotic I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a902c72a4a233b613bf86a8b20c724
https://doi.org/10.1101/2023.05.08.23289640
https://doi.org/10.1101/2023.05.08.23289640
Autor:
Jesse W. Williams, Caroline M. Ferreira, Kelly M. Blaine, Crystal Rayon, Francisco Velázquez, Jiankun Tong, Marcus E. Peter, Anne I. Sperling
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Fas (CD95/APO-1) and its ligand (FasL/CD95L) promote the resolution of type 2 lung inflammation and eosinophilia. We previously found that Fas-deficiency on T cells, but not eosinophils, delayed resolution of inflammation. However, Fas can signal bot
Externí odkaz:
https://doaj.org/article/772e426db40b46e7add92c32328026d8
Autor:
Caroline M. Ferreira, Jesse W. Williams, Jiankun Tong, Crystal Rayon, Kelly M. Blaine, Anne I. Sperling
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Asthma is characterized by chronic airway type-2 inflammation and eosinophilia, yet the mechanisms involved in chronic, non-resolving inflammation remain poorly defined. Previously, our group has found that when Rag-deficient mice were reconstituted
Externí odkaz:
https://doaj.org/article/efa28a41255d41bebe060916909bbf95
Autor:
Steven R. White, Juan J. Tena, James E. Gern, Débora R. Sobreira, Chanie L. Howard, Kevin M. Magnaye, Carole Ober, Kelly M. Blaine, José Luis Gómez-Skarmeta, Noboru J. Sakabe, Cara L. Hrusch, Anne I. Sperling, Michelle M. Stein, Marcelo A. Nobrega, Edward T. Naureckas, Donna C. Decker, Ivy Aneas, Nathan Schoetler, Lindsey E. Montefiori, Daniel J. Jackson, Douglas K. Hogarth, Matthew C. Altman, Selene M. Clay
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Genome-wide association studies (GWAS) have implicated the IL33 locus in asthma, but the underlying mechanisms remain unclear. Here, we identify a 5 kb region within the GWAS-defined segment that acts as an enhancer-blocking element in vivo and in vi
Autor:
Mario Cortese, Gregory B. Hammer, Sean N. Tucker, Katharina Röltgen, Anne I. Sperling, Christian McCrory Constantz, Scott D. Boyd, Mark M. Davis, Krishna M. Roskin, Julia Z. Adamska, D. Huw Davies, Neha Gupta, Philip L. Felgner, Iram N. Ahmad, Aarti Jain, Ben S. Wendel, Kelly M. Blaine, Fan Yang, Michael Lyons, Ameen A. Salahudeen, Lisa K. Blum, Kara D. Meister, Emery G. Dora, Lauren P. Jatt, Vamsee Mallajosyula, Katherine J. L. Jackson, William H. Robinson, Calvin J. Kuo, Peter S. Kim, Lisa E. Wagar
Publikováno v:
Nature medicine, vol 27, iss 1
Nat Med
Nature Medicine
Nat Med
Nature Medicine
Most of what we know about adaptive immunity has come from inbred mouse studies, using methods that are often difficult or impossible to confirm in humans. In addition, vaccine responses in mice are often poorly predictive of responses to those same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749ec4370f6ba55f6caa1ab0658a21f6
https://escholarship.org/uc/item/3hs0m6t8
https://escholarship.org/uc/item/3hs0m6t8
Autor:
Douglas K. Hogarth, José Luis Gómez-Skarmeta, Nathan Schoettler, Débora R. Sobreira, Cara L. Hrusch, Michelle M. Stein, Juan J. Tena, Donna C. Decker, Selene M. Clay, Noboru J. Sakabe, Kevin M. Magnaye, Edward T. Naurekas, Daniel J. Jackson, Marcelo A. Nobrega, Lindsey E. Montefiori, Steven R. White, Carole Ober, Ivy Aneas, Anne I. Sperling, Kelly M. Blaine, Matthew C. Altman, James E. Gern, Chanie L. Howard
Genome-wide association studies (GWAS) have implicated the IL33 locus in asthma, but the underlying mechanisms remain unclear. Here, we identify a 5 kb region within the GWAS-defined segment that acts as a strong regulatory element in vivo and in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2a5bc926bc1f899e6a725fdf0dea46
https://doi.org/10.21203/rs.3.rs-84333/v1
https://doi.org/10.21203/rs.3.rs-84333/v1
Autor:
Selene M. Clay, Nathan Schoetler, Daniel J. Jackson, Michelle M. Stein, Noboru J. Sakabe, Lindsey E. Montefiori, Juan J. Tena, Steven R. White, Ivy Aneas, Anne I. Sperling, Chanie L. Howard, Kelly M. Blaine, Marcelo A. Nobrega, Matthew C. Altman, Edward T. Naureckas, Donna C. Decker, Débora R. Sobreira, Carole Ober, Douglas K. Hogarth, James E. Gern, José Luis Gómez-Skarmeta, Kevin M. Magnaye, Cara L. Hrusch
Genome-wide association studies (GWAS) have implicated the IL33 locus in asthma, but the underlying mechanisms remain unclear. Here, we identify a 5 kb region within the GWAS-defined segment that acts as a strong regulatory element in vivo and in vit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1677848b9405bc49a7ca05ef7b1128d
https://doi.org/10.1101/2020.09.09.290098
https://doi.org/10.1101/2020.09.09.290098