Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelly Lee Winter"'
Autor:
James C. Whisstock, Jamie Seymour, Andrew M. Ellisdon, Rodney K. Tweten, Cyril F. Reboul, Kelly Lee Winter, Santosh Panjikar, Wayne C. Hodgson, Michelle A. Dunstone, Sheena McGowan, Peter K. Dearden, Kitmun Huynh, Christine A Oellig
Publikováno v:
Proceedings of the National Academy of Sciences. 112:15360-15365
The lethal factor in stonefish venom is stonustoxin (SNTX), a heterodimeric cytolytic protein that induces cardiovascular collapse in humans and native predators. Here, using X-ray crystallography, we make the unexpected finding that SNTX is a pore-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0597256171ecf4d85cc2ae08ff1559
https://doi.org/10.1073/pnas.1507622112
https://doi.org/10.1073/pnas.1507622112
Autor:
Mahdokht Jouiaei, Syed Abid Ali, Dolyce H.W. Low, Nicholas R. Casewell, Bryan G. Fry, Nathan Dunstan, Kate Baumann, Kelly Lee Winter, Amanda Nouwens, Jessica Anne Steuten, Kenneth D. Winkel, Paul Monagle, Ivan Koludarov, Wayne C. Hodgson, Sarah Rossi, Jordan Debono, Daryl C. Yang, Clemence Jesupret, Nadya Panagides, Larissa Kern, Eivind A. B. Undheim, Alun Jones, Timothy N.W. Jackson, Vera Ignjatovic, Laura Greisman, Robyn Summerhayes
Publikováno v:
Journal of Proteomics. 105:285-294
For over a century, venom samples from wild snakes have been collected and stored around the world. However, the quality of storage conditions for “vintage” venoms has rarely been assessed. The goal of this study was to determine whether such his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a47bb82db60e4eb10c762b9602c6448
https://doi.org/10.1016/j.jprot.2014.01.004
https://doi.org/10.1016/j.jprot.2014.01.004
Autor:
Kim Roelants, Kelly Lee Winter, Christopher Shaw, Janette A Norman, Denis B. Scanlon, Lily Wong, Bryan G. Fry, John A. Karas, Hang Fai Kwok, Wayne C. Hodgson, Laura Griesman
Publikováno v:
Molecular Biology and Evolution. 27:395-407
The origin and evolution of venom proteins in helodermatid lizards were investigated by multidisciplinary techniques. Our analyses elucidated novel toxin types resultant from three unique domain-expression processes: 1) The first full-length sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba445b44b75063bd37593bee406e638
https://doi.org/10.1093/molbev/msp251
https://doi.org/10.1093/molbev/msp251
Publikováno v:
Toxicology Letters. 187:94-98
Although CSL box jellyfish antivenom (AV) remains the primary treatment for Chironex fleckeri envenoming, there has been considerable debate regarding its clinical effectiveness. Animal studies have shown that AV is largely ineffective in preventing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad34eca2b20e177e37d60a5164507563
https://doi.org/10.1016/j.toxlet.2009.02.008
https://doi.org/10.1016/j.toxlet.2009.02.008
Autor:
Geoffrey K. Isbister, Jennifer Schneider, Nicki Konstantakopoulos, Kelly Lee Winter, Jamie Seymour, Wayne C. Hodgson
Publikováno v:
Toxicology Letters. 179:118-123
Irukandji syndrome is usually characterized by delayed severe abdominal, back and chest pain associated with autonomic effects including diaphoresis, hypertension and, in severe cases, myocardial injury and pulmonary oedema. It is most often associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f17b4d20f2bf1763e83761965f1530
https://doi.org/10.1016/j.toxlet.2008.04.011
https://doi.org/10.1016/j.toxlet.2008.04.011
Autor:
Geoffrey K. Isbister, Ross Fernando, Wayne C. Hodgson, Jamie Seymour, Kelly Lee Winter, Sharmaine Ramasamy
Publikováno v:
Toxicology Letters. 168:13-20
Clinical observations suggest a primary cardiotoxic role in fatal Chironex fleckeri stings. The limited research available indicates that Chiropsella bronzie venom acts in a similar manner although appears to be less potent. The aim of the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13573c423ccefd0da8be4ec9f8d0afe
https://doi.org/10.1016/j.toxlet.2006.10.011
https://doi.org/10.1016/j.toxlet.2006.10.011
Autor:
Lily Wong, Wayne C. Hodgson, Kim Roelants, Laurence J. Miller, J McNaughtan, Holger Scheib, Feng Lin, Hang Fai Kwok, Denis B. Scanlon, Matthias J.P. van Osch, Laura Greisman, Elazar Kochva, Wouter M. Teeuwisse, John A. Karas, Bryan G. Fry, Rob J.A. Nabuurs, Kelly Lee Winter, Janette A Norman, Sanjaya Kuruppu, Christopher Shaw, Fan Gao, Louise van der Weerd
Publikováno v:
Molecular and Cellular Proteomics, 9(11), 2369-2390
Vrije Universiteit Brussel
Vrije Universiteit Brussel
Venom has only been recently discovered to be a basal trait of the Anguimorpha lizards. Consequently, very little is known about the timings of toxin recruitment events, venom protein molecular evolution, or even the relative physical diversification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66a133d3a3c2b3982a80d38d5c5ca55
https://hdl.handle.net/1887/109655
https://hdl.handle.net/1887/109655
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 57(1)
Metabolic expenditure has been shown to increase abruptly in several snake species directly after venom expenditure, while the later stages of venom replenishment seem to involve minor costs. This study examines the dependence of increases in metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9298f5c7e6f0faf0c527e02882239b8
https://pubmed.ncbi.nlm.nih.gov/20937295
https://pubmed.ncbi.nlm.nih.gov/20937295
Autor:
Jeanette Ingle, Colin R. McHenry, Ellie J C Goldstein, Wouter M. Teeuwisse, Kim Roelants, Christofer J. Clemente, Janette A Norman, Stephen Wroe, Diane M Citron, Eleni Giannakis, Denis B. Scanlon, Matthias J.P. van Osch, Karthiyani Krishnasamy, J McNaughtan, John A. Karas, Toni L. Ferrara, Hang Fai Kwok, Louise van der Weerd, Paolo Martelli, Elazar Kochva, Kelly Lee Winter, Laura Greisman, Sonja Luz, Wayne C. Hodgson, Bryan G. Fry, Holger Scheib, Karen Moreno, Phillip D. Clausen
The predatory ecology of Varanus komodoensis (Komodo Dragon) has been a subject of long-standing interest and considerable conjecture. Here, we investigate the roles and potential interplay between cranial mechanics, toxic bacteria, and venom. Our an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0848393dc49932fb63b1c0f9d11a760f
https://hdl.handle.net/20.500.14017/7cd26bf5-4177-4000-9d9a-2aa3fca87431
https://hdl.handle.net/20.500.14017/7cd26bf5-4177-4000-9d9a-2aa3fca87431
An in vivo examination of the stability of venom from the Australian box jellyfish Chironex fleckeri
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 49(6)
We have previously characterised the pharmacological activity of a number of jellyfish venoms with a particular emphasis on the profound cardiovascular effects. It has been suggested that jellyfish venoms are difficult to work with and are sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b72ce2020e7e268b228c1b59b0c263
https://pubmed.ncbi.nlm.nih.gov/17215014
https://pubmed.ncbi.nlm.nih.gov/17215014