Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kelly Lammerts van Bueren"'
Autor:
Tanvi Sinha, Kelly Lammerts van Bueren, Diane E. Dickel, Ivana Zlatanova, Reuben Thomas, Carlos O. Lizama, Shan-Mei Xu, Ann C. Zovein, Kohta Ikegami, Ivan P. Moskowitz, Katherine S. Pollard, Len A. Pennacchio, Brian L. Black
Publikováno v:
Cell reports, vol 39, iss 9
Endothelial and erythropoietic lineages arise from a common developmental progenitor. Etv2 is a master transcriptional regulator required for the development of both lineages. However, the mechanisms through which Etv2 initiates the gene-regulatory n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe8b259ed60c42c8752d006795b3252
https://escholarship.org/uc/item/42670783
https://escholarship.org/uc/item/42670783
Autor:
Wouter de Laat, Yiwen Zhu, Iris Barshack, Corina Hartman, Devin Coleman-Derr, Christopher N. Mayhew, Robert Kleta, E.K. Ruzzo, Diane E. Dickel, Brian L. Black, James M. Wells, Ralston M. Barnes, E.S. Vos, Ifat Bar-Joseph, Matthew F. Kuhar, Yair Anikster, Horia Stanescu, Roni Milgrom, Pavlo Tatarskyy, David Goldstein, Amy Pitstick, Haike Reznik-Wolf, Marco Osterwalder, Axel Visel, Mehmet Tekman, Denise M. Imai, Raanan Shamir, Ben Pode-Shakked, Len A. Pennacchio, Danit Oz-Levi, Kelly Lammerts van Bueren, Rivka Shapiro, Iros Barozzi, Yujun Han, Dina Marek-Yagel, Tsviya Olender, Anna Alkelai, Veena Afzal, Elon Pras, Batia Weiss, Alexander Nord, Michael Schvimer, Doron Lancet
Publikováno v:
Nature, vol 571, iss 7763
Nature, 571(7763), 107-111. Nature Publishing Group
Nature, 571(7763), 107-111. Nature Publishing Group
Large-scale genome sequencing is poised to provide a substantial increase in the rate of discovery of disease-associated mutations, but the functional interpretation of such mutations remains challenging. Here we show that deletions of a sequence on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb3250bb97b0f0a5cf26e8daa676462
https://doi.org/10.1038/s41586-019-1312-2
https://doi.org/10.1038/s41586-019-1312-2
Publikováno v:
Developmental biology, vol 445, iss 2
MEF2C is a member of the highly conserved MEF2 family of transcription factors and is a key regulator of cardiovascular development. In mice, Mef2c is expressed in the developing heart and vasculature, including the endothelium. Loss of Mef2c functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a680751294cc2343ea7446419f663069
https://pubmed.ncbi.nlm.nih.gov/30521808
https://pubmed.ncbi.nlm.nih.gov/30521808
Autor:
Sean Lovett, Stephen C. J. Parker, Holly Coleman, Narisu Narisu, D. Leland Taylor, Morgan Park, Len A. Pennacchio, Taccara Johnson, Jenny McDowell, Baishali Maskeri, Meg Vemulapalli, Axel Visel, April Hargrove, Jennifer A. Akiyama, James Thomas, Michael R. Erdos, Cathy Masiello, Michael D. Gregory, Brian L. Schmidt, Peter S. Chines, Michael L. Stitzel, Quino Maduro, Betty Benjamin, Shi-ling Ho, Robert W. Blakesley, Xiaobin Guan, Francis S. Collins, Karen Schandler, Mal Stantripop, Casandra Montemayor, Richelle Legaspi, Jesse Becker, Kelly Lammerts van Bueren, Alice Young, Nancy Riebow, James C. Mullikin, Christina Sison, Jyoti Gupta, Nisc Comparative Sequencing Program, Mila Dekhtyar, Joel Han, Jose M. Orozco, Brian L. Black, Pam Thomas, Shelise Brooks, Gerry Bouffard
Publikováno v:
Proceedings of the National Academy of Sciences. 110:17921-17926
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcripto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2966a51d8f04562c79bd26ef7f5490
https://doi.org/10.1073/pnas.1317023110
https://doi.org/10.1073/pnas.1317023110
Autor:
Shoumo Bhattacharya, Dorota Szumska, Kelly Lammerts van Bueren, Wolfgang Wurst, Rebekah J. Ashmore, Peter J. Scambler, Iain M. Dykes, Thomas Floss
Publikováno v:
Circulation research 115(1), 23-31 (2014). doi:10.1161/CIRCRESAHA.115.303300
Europe PubMed Central
Circ. Res. 115, 23-31 (2014)
Europe PubMed Central
Circ. Res. 115, 23-31 (2014)
Rationale : 22q11 deletion syndrome arises from recombination between low-copy repeats on chromosome 22. Typical deletions result in hemizygosity for TBX1 associated with congenital cardiovascular disease. Deletions distal to the typically deleted re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d7a3e76582417105d72220c7998ab8
https://ora.ox.ac.uk/objects/uuid:afa7f2dc-bf94-41db-b6ff-c06659fd44c7
https://ora.ox.ac.uk/objects/uuid:afa7f2dc-bf94-41db-b6ff-c06659fd44c7
Publikováno v:
Current Opinion in Hematology. 19:199-205
Purpose of review Vasculogenesis and hematopoiesis are essential for development. Recently, the ETS domain transcription factor Etv2 has been identified as an essential regulator of vasculogenesis and hematopoiesis. Here, we review the recent studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59f1a71100daf583392969b7bda14dc
https://doi.org/10.1097/moh.0b013e3283523e07
https://doi.org/10.1097/moh.0b013e3283523e07
Autor:
Christelle Adolphe, Carol Wicking, Josephine Bowles, Barbara A. Leggett, Michael Walsh, Jennifer S. Bennetts, Lindsay F. Fowles, Joanne P. Young, Natalie C. Butterfield, Kelly Lammerts van Bueren, Fiona Simpson, Lisa A. Simms
Publikováno v:
Experimental Cell Research. 312:73-85
The KIAA0101/p15(PAF)/OEATC-1 protein was initially isolated in a yeast two-hybrid screen for proliferating cell nuclear antigen (PCNA) binding partners, and was shown to bind PCNA competitively with the cell cycle regulator p21(WAF). PCNA is involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a41a6e61d8b6d8ff5ca743d1cf9053
https://doi.org/10.1016/j.yexcr.2005.09.020
https://doi.org/10.1016/j.yexcr.2005.09.020
Autor:
Salvatore Fiorenza, Carol Wicking, Maria de Fatima Bonaldo, Edwina McGlinn, Chi-chung Hui, Kelly Lammerts van Bueren, Marcelo B. Soares, Alistair R. R. Forrest, Rong Mo, Alisa M. Poh, Sean M. Grimmond, Brandon J. Wainwright
Publikováno v:
Mechanisms of Development. 122:1218-1233
From early in limb development the transcription factor Gli3 acts to define boundaries of gene expression along the anterior-posterior (AP) axis, establishing asymmetric patterns required to provide positional information. As limb development proceed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6f79d38993e2f2687d97db51339c6f
https://doi.org/10.1016/j.mod.2005.06.012
https://doi.org/10.1016/j.mod.2005.06.012
Autor:
Peter J. Scambler, Amelie Calmont, Francesca Rochais, Shoumo Bhattacharya, Kerra Pearce, Robert G. Kelly, Kelly Lammerts van Bueren, Irinna Papangeli, Catherine Roberts, Dorota Szumska
Publikováno v:
Developmental Biology
Developmental Biology, Elsevier, 2010, 340 (2), pp.369-80. ⟨10.1016/j.ydbio.2010.01.020⟩
Developmental Biology, Elsevier, 2010, 340 (2), pp.369-80
Developmental Biology; Vol 340
Developmental Biology, 2010, 340 (2), pp.369-80. ⟨10.1016/j.ydbio.2010.01.020⟩
Developmental Biology, Elsevier, 2010, 340 (2), pp.369-80. ⟨10.1016/j.ydbio.2010.01.020⟩
Developmental Biology, Elsevier, 2010, 340 (2), pp.369-80
Developmental Biology; Vol 340
Developmental Biology, 2010, 340 (2), pp.369-80. ⟨10.1016/j.ydbio.2010.01.020⟩
22q11 deletion syndrome (22q11DS) is characterised by aberrant development of the pharyngeal apparatus and the heart with haploinsufficiency of the transcription factor TBX1 being considered the major underlying cause of the disease. Tbx1 mutations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a9e21fb6c404166baed2f88b934683
https://hal.archives-ouvertes.fr/hal-00505943
https://hal.archives-ouvertes.fr/hal-00505943
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b46e59ad738ba2dd988eba6be15f8ac
https://doi.org/10.1038/nprot.2009.164
https://doi.org/10.1038/nprot.2009.164