Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kelly L. Sharp"'
Autor:
MyLinh T. Duong, Matthew R. Collinson-Pautz, Eva Morschl, An Lu, Slawomir P. Szymanski, Ming Zhang, Mary E. Brandt, Wei-Chun Chang, Kelly L. Sharp, Steven M. Toler, Kevin M. Slawin, Aaron E. Foster, David M. Spencer, J. Henri Bayle
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 124-137 (2019)
Use of chimeric antigen receptors (CARs) as the basis of targeted adoptive T cell therapies has enabled dramatic efficacy against multiple hematopoietic malignancies, but potency against bulky and solid tumors has lagged, potentially due to insuffici
Externí odkaz:
https://doaj.org/article/2fbebd3dad654aee828c680d5ac36e2b
Autor:
J. Henri Bayle, Aaron E. Foster, David M. Spencer, Kelly L. Sharp, Xiaomei Wang, Fabricio G. Cabrera
Publikováno v:
Mol Ther
Allogeneic, off-the-shelf (OTS) chimeric antigen receptor (CAR) cell therapies have the potential to reduce manufacturing costs and variability while providing broader accessibility to cancer patients and those with other diseases. However, host-vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28db584d332ff81077518a508b7e85d
https://doi.org/10.1016/j.ymthe.2020.10.019
https://doi.org/10.1016/j.ymthe.2020.10.019
Autor:
An Lu, Kelly L. Sharp, Wei-Chun Chang, Kevin M. Slawin, Slawomir P. Szymanski, Steven M. Toler, Ming Zhang, Eva Morschl, David M. Spencer, Matthew R. Collinson-Pautz, My Linh T. Duong, J. Henri Bayle, Mary E. Brandt, Aaron E. Foster
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss, Pp 124-137 (2019)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Use of chimeric antigen receptors (CARs) as the basis of targeted adoptive T cell therapies has enabled dramatic efficacy against multiple hematopoietic malignancies, but potency against bulky and solid tumors has lagged, potentially due to insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea3ccbe3a4f7ff4b8f73320ec846449
http://www.sciencedirect.com/science/article/pii/S2372770518300469
http://www.sciencedirect.com/science/article/pii/S2372770518300469
Autor:
Aaron E. Foster, J. Henri Bayle, Xiaomei Wang, Aruna Mahendravada, Alan D. Guerrero, Mary E. Brandt, MyLinh Duong, Christine Gagliardi, Kelly L. Sharp
Publikováno v:
Blood. 136:39-40
Background: Natural Killer (NK) cells possess potent innate anti-tumor cytotoxicity that can be augmented and focused by engineering with chimeric antigen receptors (CARs). Because NK cells do not express T cell receptors that can direct alloreactivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54eebf425945925ae56410212faf3a4f
https://doi.org/10.1182/blood-2020-140848
https://doi.org/10.1182/blood-2020-140848
Autor:
Kelly L. Sharp, MyLinh Duong, J. Henri Bayle, Aaron E. Foster, Aruna Mahendravada, Mary E. Brandt
Publikováno v:
Cancer Research. 80:2194-2194
Background: Chimeric antigen receptor (CAR) T cell therapy targeting solid tumors is challenged by inhibitory signals in the tumor microenvironment that may lead to CAR-T exhaustion. Previously, we described a GoCAR platform that uses a rimiducid (Ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e34f0d7628b62cf7ad3043708863322
https://doi.org/10.1158/1538-7445.am2020-2194
https://doi.org/10.1158/1538-7445.am2020-2194