Benzo(a)pyrene-induced cytotoxicity, cell proliferation, DNA damage, and altered gene expression profiles in HT-29 human colon cancer cells

Autor: Kelly L. Harris, Perumalla V Rekhadevi, Siddharth Pratap, Jeremy N. Myers, Aramandla Ramesh

Publikováno v: Cell Biology and Toxicology. 37:891-913

In the US alone, around 60,000 lives/year are lost to colon cancer. In order to study the mechanisms of colon carcinogenesis, in vitro model systems are required in addition to in vivo models. Towards this end, we have used the HT-29 colon cancer cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cba0fe9ad88e9b3fd9fd5fd93065d315
https://doi.org/10.1007/s10565-020-09579-5

Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk

Autor: Rosalie K. Elespuru, Kelly L Harris, Karen L. McKim, Meagan B. Myers, Barbara L. Parsons

Publikováno v: Environmental and Molecular Mutagenesis

Cancer driver mutations (CDMs) are necessary and causal for carcinogenesis and have advantages as reporters of carcinogenic risk. However, little progress has been made toward developing measurements of CDMs as biomarkers for use in cancer risk asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73da9ccdf65721c7ae812c5754ce8063
https://doi.org/10.1002/em.22326

Benzo(a)pyrene-induced cytotoxicity, cell proliferation, DNA damage, and altered gene expression profiles in HT-29 human colon cancer cells

Autor: Jeremy N, Myers, Kelly L, Harris, Perumalla V, Rekhadevi, Siddharth, Pratap, Aramandla, Ramesh

Publikováno v: Cell biology and toxicology. 37(6)

In the US alone, around 60,000 lives/year are lost to colon cancer. In order to study the mechanisms of colon carcinogenesis, in vitro model systems are required in addition to in vivo models. Towards this end, we have used the HT-29 colon cancer cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e98548b9f714370b794125b98f62dc1
https://pubmed.ncbi.nlm.nih.gov/33411230

Contributors

Autor: Arturo Anadón, Vellareddy Anantharam, Anthony E. Archibong, Irma Ares, Adam D. Aulbach, Nikee Awasthee, Aryamitra Banerjee, Leah D. Banks, Frank A. Barile, Sudheer R. Beedanagari, Charalampos Belantis, Enrico Bergamaschi, Sadikshya Bhandari, Sneha P. Bhatia, Karyn Bischoff, David J. Borts, Emily Brehm, Subash Chandra Gupta, Saurabh Chatterjee, Catheryne Chiang, Anirudh J. Chintalapati, P. Cohn, Robert W. Coppock, Lucio G. Costa, Tirupapuliyur V. Damodaran, Clinton D'Souza, Wolf-D. Dettbarn, Amy A. Devlin, Robin B. Doss, Shiwangi Dwivedi, Margitta M. Dziwenka, Jorge Estévez, Daniel S. Fabricant, A.M. Fan, Vanessa A. Fitsanakis, John Flaskos, Jodi A. Flaws, Swaran J.S. Flora, Sue M. Ford, Jessica S. Fortin, Domniki Fragou, Shayne C. Gad, Bianca Galateanu, Dale R. Gardner, George Georgiadis, Fernando Gil, Saryu Goel, Mary Gulumian, P.K. Gupta, Ramesh C. Gupta, Rekha K. Gupta, Sharon Gwaltney-Brant, Alan J. Hargreaves, Kelly L. Harris, Kenneth J. Harris, Holly E. Hatfield, Wallace A. Hayes, Ioannis Heretis, Antonio F. Hernández, Corey J. Hilmas, Darryl B. Hood, Pasi Huuskonen, Stewart B. Jacobson, Sandra A. James-Yi, Huajun Jin, Jun Kanno, Arthi Kanthasamy, Anumantha G. Kanthasamy, Shilpa N. Kaore, Navinchandra M. Kaore, Bhupendra S. Kaphalia, Vesa Karttunen, Gurjot Kaur, Ravneet Kaur, Prasada Rao S. Kodavanti, Urmila P. Kodavanti, George A. Kontadakis, Gopala Krishna, Priya A. Krishna, Kavya A. Krishna, Maria Kummu, George D. Kymionis, Rajiv Lall, P. Lin, Bommanna G. Loganathan, Jarkko Loikkanen, Marcello Lotti, Michael A. Lynes, Brinda Mahadevan, Jitendra K. Malik, Charalampos Mamoulakis, Jane A. Mantey, María Rosa Martínez-Larrañaga, María Aránzazu Martínez, Charalampos Mavridis, Roger O. McClellan, Vincent P. Meador, Lars Friis Mikkelsen, Dejan Milatovic, Ida R. Miller Mukherjee, Anupama Mukherjee, Pushpinder Kaur Multani, Päivi Myllynen, Kirsi Myöhänen, Rekek Negga, Carolina Negrei, Meliton N. Novilla, Stephanie Padilla, Carlos M. Palmeira, Kip E. Panter, Markku Pasanen, Daniel J. Patrick, Sofia Pavanello, Henrik Duelund Pedersen, Olavi Pelkonen, Michael A. Pellizzon, Jason Pitt, Argyro Plaka, Aramandla Ramesh, Saniya Rattan, Jenni Repo, Matthew R. Ricci, Anabela P. Rolo, Magdalini Sachana, Heidi Sahlman, Nitin Saini, Vandana Saini, Kai Savolainen, Ratanesh Kumar Seth, Abha Sharma, Anurag Sharma, Elina Sieppi, Rui Silva, Anita Sinha, Iordanis Skamagkas, Samantha J. Snow, Miguel A. Sogorb, Ajay Srivastava, Szabina A. Stice, Markus Storvik, David T. Szabo, João S. Teodoro, Aristidis M. Tsatsakis, John Tsiaoussis, Kirsi Vähäkangas, Sumit Singh Verma, Eugenio Vilanova, Suryanarayana V. Vulimiri, Genoa R. Warner, Kevin D. Welch, Christina Wilson-Frank, S.H. You, Snjezana Zaja-Milatovic, Ioannis E. Zisis, Csaba K. Zoltani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5da5a009880ef9604908d9dca3addf8c
https://doi.org/10.1016/b978-0-12-814655-2.01002-1

Polycyclic Aromatic Hydrocarbons and Digestive Tract Cancers: A Perspective

Autor: Perumalla V. Rekhadevi, Mohammad S. Niaz, Kelly L. Harris, Ashley C. Huderson, Deacqunita L. Diggs, Jeremy N. Myers, Leah D. Banks, Aramandla Ramesh

Publikováno v: Journal of Environmental Science and Health, Part C. 29:324-357

Cancers of the colon are most common in the Western world. In majority of these cases, there is no familial history and sporadic gene damage seems to play an important role in the development of tumors in the colon. Studies have shown that environmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f11b2a956e5c1e38c676ce81d05ac6
https://doi.org/10.1080/10590501.2011.629974