Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kelly L. Damm-Ganamet"'
Autor:
Aaron A. Thompson, Michael B. Harbut, Pei-Pei Kung, Nathan K. Karpowich, Jeffrey D. Branson, Joanna C. Grant, Deborah Hagan, Heather A. Pascual, Guoyun Bai, Reza Beheshti Zavareh, Heather R. Coate, Bernard C. Collins, Marjorie Côte, Christine F. Gelin, Kelly L. Damm-Ganamet, Hadi Gholami, Adam R. Huff, Luis Limon, Kevin J. Lumb, Puiying A. Mak, Kohki M. Nakafuku, Edmund V. Price, Amy Y. Shih, Mandana Tootoonchi, Nadeem A. Vellore, Jocelyn Wang, Na Wei, Jeannie Ziff, Scott B. Berger, James P. Edwards, Agnès Gardet, Siquan Sun, Jennifer E. Towne, Jennifer D. Venable, Zhicai Shi, Hariharan Venkatesan, Marie-Laure Rives, Sujata Sharma, Brock T. Shireman, Samantha J. Allen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
NKG2D (natural-killer group 2, member D) is a homodimeric transmembrane receptor that plays an important role in NK, γδ + , and CD8 + T cell-mediated immune responses to environmental stressors such as viral or bacterial infections and oxidative st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d48b50bde14ca39eb944d361970a99
https://doi.org/10.1073/pnas.2216342120
https://doi.org/10.1073/pnas.2216342120
Autor:
Kelly L. Damm-Ganamet, Alan D. Wickenden, Taraneh Mirzadegan, Marie-Laure Rives, Heather M. McAllister
Publikováno v:
J Biol Chem
Excitatory amino acid transporters (EAATs) represent a protein family that is an emerging drug target with great therapeutic potential for managing central nervous system disorders characterized by dysregulation of glutamatergic neurotransmission. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d110c0bb332f0e5ce669aeea4b3a2edf
https://doi.org/10.1074/jbc.ac119.011190
https://doi.org/10.1074/jbc.ac119.011190
Autor:
Renee L. DesJarlais, Tami Marrone, Jamie M. Schiffer, Amy Y. Shih, Taraneh Mirzadegan, Kelly L. Damm-Ganamet, Laura Pérez-Benito
Publikováno v:
Journal of Medicinal Chemistry. 63:1929-1936
The topic of gender equality within the United States workforce is receiving a great deal of attention. The field of chemistry is no exception and is increasingly focused on taking steps to achieve gender diversity within the chemistry workforce. Ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714622272a902f3d98fc482c6a5dad2e
https://doi.org/10.1021/acs.jmedchem.9b01512
https://doi.org/10.1021/acs.jmedchem.9b01512
Autor:
Kelly L, Damm-Ganamet, Renee L, DesJarlais, Tami, Marrone, Amy Y, Shih, Jamie M, Schiffer, Laura, Perez-Benito, Taraneh, Mirzadegan
Publikováno v:
Journal of medicinal chemistry. 63(5)
The topic of gender equality within the United States workforce is receiving a great deal of attention. The field of chemistry is no exception and is increasingly focused on taking steps to achieve gender diversity within the chemistry workforce. Ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba5fad6079a446aa32eea26fe7bfe24c
https://pubmed.ncbi.nlm.nih.gov/31913036
https://pubmed.ncbi.nlm.nih.gov/31913036
Publikováno v:
Biophysical Journal. 114:32-39
The stimulator-of-interferon-genes (STING) protein is involved in innate immunity. It has recently been shown that modulation of STING can lead to an aggressive antitumor response. DMXAA is an antitumor agent that had shown great promise in murine mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d599e08c8cefcabe54ca0736416317f2
https://doi.org/10.1016/j.bpj.2017.10.027
https://doi.org/10.1016/j.bpj.2017.10.027
Autor:
Taraneh Mirzadegan, Navin Rao, Alec D. Lebsack, Kelly L. Damm-Ganamet, Nidhi Arora, John J. M. Wiener, James P. Edwards, Stéphane Bécart, Lori Westover, Marina I. Nelen, Heather M. McAllister
Publikováno v:
Journal of chemical information and modeling. 59(5)
At the onset of a drug discovery program, the goal is to identify novel compounds with appropriate chemical features that can be taken forward as lead series. Here, we describe three prospective case studies, Bruton Tyrosine Kinase (BTK), RAR-Related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbade40c3c722e76c4ce85a5dd9e29c6
https://pubmed.ncbi.nlm.nih.gov/30817167
https://pubmed.ncbi.nlm.nih.gov/30817167
Autor:
Catherine E. Peishoff, Donald O. Somers, Heather A. Carlson, Aqeel Ahmed, Michael Kranz, Kelly L. Damm-Ganamet, Richard D. Smith, Jeanne A. Stuckey, James B. Dunbar, Guanglei Cui, Millard H. Lambert, Patricia A. Elkins, Máire A. Convery
Publikováno v:
Journal of Chemical Information and Modeling. 56:1063-1077
The 2014 CSAR Benchmark Exercise was the last community-wide exercise that was conducted by the group at the University of Michigan, Ann Arbor. For this event, GlaxoSmithKline (GSK) donated unpublished crystal structures and affinity data from in-hou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425d373351999c72a51aef450c547183
https://doi.org/10.1021/acs.jcim.5b00523
https://doi.org/10.1021/acs.jcim.5b00523
Autor:
Daniel DiSepio, Kelly L. Damm-Ganamet, Danielle Peeters, Scott D. Bembenek, Heather M. McAllister, James P. Edwards, Lieve Mangelschots, Taraneh Mirzadegan, Jennifer Venable, Glenda Castro
Publikováno v:
Journal of medicinal chemistry. 59(9)
Here, we report a high-throughput virtual screening (HTVS) study using phosphoinositide 3-kinase (both PI3Kγ and PI3Kδ). Our initial HTVS results of the Janssen corporate database identified small focused libraries with hit rates at 50% inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba06808978408c3c82e2f12502f01e1a
https://pubmed.ncbi.nlm.nih.gov/27043133
https://pubmed.ncbi.nlm.nih.gov/27043133