Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Kelly L, Wyres"'
Autor:
Thomas D. Stanton, Kelly L. Wyres
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105331- (2024)
Externí odkaz:
https://doaj.org/article/8aa4a85d26b5454ab846b534058f4975
Autor:
Elsa D. Ibáñez-Prada, Ingrid G. Bustos, Enrique Gamboa-Silva, Diego F. Josa, Lina Mendez, Yuli V. Fuentes, Cristian C. Serrano-Mayorga, Oscar Baron, Alejandra Ruiz-Cuartas, Edwin Silva, Louise M. Judd, Taylor Harshegyi, Hector F. Africano, Juan Urrego-Reyes, Claudia C. Beltran, Sebastian Medina, Rafael Leal, Andrew J. Stewardson, Kelly L. Wyres, Jane Hawkey, Luis Felipe Reyes
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT In this study, the genetic differences and clinical impact of the carbapenemase-encoding genes among the community and healthcare-acquired infections were assessed. This retrospective, multicenter cohort study was conducted in Colombia and i
Externí odkaz:
https://doaj.org/article/ce057785c1be4472ba264e236e441dde
Autor:
Andrew J Barnes, Emma F Bennett, Ben Vezina, Andrew W Hudson, Giovanna E Hernandez, Noah A Nutter, Andrew S Bray, Ravinder Nagpal, Kelly L Wyres, M Ammar Zafar
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012189 (2024)
Successful microbial colonization of the gastrointestinal (GI) tract hinges on an organism's ability to overcome the intense competition for nutrients in the gut between the host and the resident gut microbiome. Enteric pathogens can exploit ethanola
Externí odkaz:
https://doaj.org/article/29f40d9fc7a247ef85b0bbf180dddd09
Autor:
Kai Zhou, Chun-Xu Xue, Tingting Xu, Ping Shen, Sha Wei, Kelly L. Wyres, Margaret M. C. Lam, Jinquan Liu, Haoyun Lin, Yunbo Chen, Kathryn E. Holt, the BRICS Working Group, Yonghong Xiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Adaptation to selective pressures is crucial for clinically important pathogens to establish epidemics, but the underlying evolutionary drivers remain poorly understood. The current epidemic of carbapenem-resistant Klebsiella pneumoniae (CRK
Externí odkaz:
https://doaj.org/article/c7c5d62175a5437ebca8361f90f840d3
Autor:
Ben Vezina, Stephen C Watts, Jane Hawkey, Helena B Cooper, Louise M Judd, Adam WJ Jenney, Jonathan M Monk, Kathryn E Holt, Kelly L Wyres
Publikováno v:
eLife, Vol 12 (2023)
Metabolic capacity can vary substantially within a bacterial species, leading to ecological niche separation, as well as differences in virulence and antimicrobial susceptibility. Genome-scale metabolic models are useful tools for studying the metabo
Externí odkaz:
https://doaj.org/article/069d1f508f10446c9f41211db9a4e5c9
Autor:
Kelly L. Wyres, Andries van Tonder, Lotte M. Lambertsen, Regine Hakenbeck, Julian Parkhill, Stephen D. Bentley, Angela B. Brueggemann
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/43ee615a26324fc7b14072dcf882a197
Autor:
Jane Hawkey, Kelly L. Wyres, Louise M. Judd, Taylor Harshegyi, Luke Blakeway, Ryan R. Wick, Adam W. J. Jenney, Kathryn E. Holt
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Resistance to third-generation cephalosporins, often mediated by extended-spectrum beta-lactamases (ESBLs), is a considerable issue in hospital-associated infections as few drugs remain for treatment. ESBL genes are often located
Externí odkaz:
https://doaj.org/article/9dc4899a1e9347138f68c7c929938c06
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Infections caused by Klebsiella oxytoca are the second most common cause of Klebsiella infections in humans. Most studies have focused on K. oxytoca outbreaks and few have examined the broader clinical context of K. oxytoca. Metho
Externí odkaz:
https://doaj.org/article/ca1b399c9ad6459582933d61857c04e9
Autor:
Claire L. Gorrie, Mirjana Mirčeta, Ryan R. Wick, Louise M. Judd, Margaret M. C. Lam, Ryota Gomi, Iain J. Abbott, Nicholas R. Thomson, Richard A. Strugnell, Nigel F. Pratt, Jill S. Garlick, Kerrie M. Watson, Peter C. Hunter, David V. Pilcher, Steve A. McGloughlin, Denis W. Spelman, Kelly L. Wyres, Adam W. J. Jenney, Kathryn E. Holt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Klebsiella pneumoniae is an opportunistic pathogen of increasing public health concern due to the prevalence of antimicrobial resistance. Here, the authors provide insight into the resistance profiles, bacterial genome features and virulence genes, i
Externí odkaz:
https://doaj.org/article/305d3d05cdcf4eeebbe577d8739d0a3c
Autor:
Ryan R. Wick, Louise M. Judd, Louise T. Cerdeira, Jane Hawkey, Guillaume Méric, Ben Vezina, Kelly L. Wyres, Kathryn E. Holt
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract While long-read sequencing allows for the complete assembly of bacterial genomes, long-read assemblies contain a variety of errors. Here, we present Trycycler, a tool which produces a consensus assembly from multiple input assemblies of the
Externí odkaz:
https://doaj.org/article/740f7969f10d4909b1310e844a757def