Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Kelly L, Drew"'
Autor:
Kelly L. Drew, Saurav Bhowmick, Bernard W. Laughlin, Anna V. Goropashnaya, Øivind Tøien, M. Hoshi Sugiura, Ardy Wong, Kambiz Pourrezaei, Zeinab Barati, Chao-Yin Chen
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Targeted temperature management (TTM) is standard of care for neonatal hypoxic ischemic encephalopathy (HIE). Prevention of fever, not excluding cooling core body temperature to 33°C, is standard of care for brain injury post cardiac arrest. Althoug
Externí odkaz:
https://doaj.org/article/0e64fe960aa641c1b9f01b4d3f6b762e
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Thermoregulation is necessary to maintain energy homeostasis. The novel discovery of brown adipose tissue (BAT) in humans has increased research interests in better understanding BAT thermogenesis to restore energy balance in metabolic disorders. The
Externí odkaz:
https://doaj.org/article/e698542c030a40a8a1c9e982270376eb
Autor:
David M Raizen, Janet Mullington, Christelle Anaclet, Gerard Clarke, Hugo Critchley, Robert Dantzer, Ronald Davis, Kelly L Drew, Josh Fessel, Patrick M Fuller, Erin M Gibson, Mary Harrington, W Ian Lipkin, Elizabeth B Klerman, Nancy Klimas, Anthony L Komaroff, Walter Koroshetz, Lauren Krupp, Anna Kuppuswamy, Julie Lasselin, Laura D Lewis, Pierre J Magistretti, Heidi Y Matos, Christine Miaskowski, Andrew H Miller, Avindra Nath, Maiken Nedergaard, Mark R Opp, Marylyn D Ritchie, Dragana Rogulja, Asya Rolls, John D Salamone, Clifford Saper, Vicky Whittemore, Glenn Wylie, Jarred Younger, Phyllis C Zee, H Craig Heller
Publikováno v:
SLEEP.
A workshop titled “Beyond the Symptom: The Biology of Fatigue” was held virtually September 27-28, 2021. It was jointly organized by the Sleep Research Society and the Neurobiology of Fatigue Working Group of the NIH Blueprint Neuroscience Resear
Autor:
Fiammetta Zanetti, Chao-Yin Chen, Hailey A. Baker, M. Hoshi Sugiura, Kelly L. Drew, Zeinab Barati
Publikováno v:
Physiological and Biochemical Zoology. :000-000
Publikováno v:
Journal of Neurochemistry. 151:316-335
Hibernation is a seasonal phenomenon characterized by a drop in metabolic rate and body temperature. Adenosine A1 receptor agonists promote hibernation in different mammalian species, and the understanding of the mechanism inducing hibernation will i
Autor:
Sherri L Christian, Tanna eRoe, Brian T Rasley, Jeanette eMoore, Michael B Harris, Kelly L Drew
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Hibernation is a unique physiological adaptation characterized by periods of torpor that consist of repeated, reversible and dramatic reductions of body temperature, metabolism and blood flow. External and internal triggers can induce arousal from to
Externí odkaz:
https://doaj.org/article/fc399a5d48e541488206951b5d8e86bc
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107493 (2014)
Hemorrhagic shock (HS) following trauma is a leading cause of death among persons under the age of 40. During HS the body undergoes systemic warm ischemia followed by reperfusion during medical intervention. Ischemia/reperfusion (I/R) results in a di
Externí odkaz:
https://doaj.org/article/678318bdbbc44a4e97bafa4db5990323
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94225 (2014)
Cardiac arrest (CA) and hemorrhagic shock (HS) are two clinically relevant situations where the body undergoes global ischemia as blood pressure drops below the threshold necessary for adequate organ perfusion. Resistance to ischemia/reperfusion (I/R
Externí odkaz:
https://doaj.org/article/1a9eedab246641d3af7518eaec6f02f8
Autor:
C. Frare, Kelly L. Drew
Publikováno v:
J Chem Neuroanat
Hibernation is a seasonal strategy to conserve energy, characterized by modified thermoregulation, an increase in sleep pressure and drastic metabolic changes. Glial cells such as astrocytes and tanycytes are the brain metabolic sensors, but it remai
Autor:
Saurav Bhowmick, Kelly L. Drew
Publikováno v:
Free Radical Biology and Medicine. 113:203-211
Cerebral ischemia-reperfusion (I/R) injury initiates a cascade of events, generating nitric oxide (NO) and superoxide(O 2 •- ) to form peroxynitrite (ONOO - ), a potent oxidant. Arctic ground squirrels (AGS; Urocitellus parryii ) show high toleranc