Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kelly Kugler"'
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplemental Table 7: Cases with two or more oncogenic driver alterations. Supplemental Table 8. Comparison of LCMC I and LCMC II.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220c9bfb87c6e273b0091ae22c15ae02
https://doi.org/10.1158/1078-0432.22465377
https://doi.org/10.1158/1078-0432.22465377
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplemental Table 1. Institutions and PIs participating in LCMC II; Supplemental Table 2. Overview of mutational profiling platforms employed across 16 LCMC2 testing sites; Supplemental Table 3. Mutations in the core genes assayed in LCMC II; Supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c17db35275ebf7a6182fbd83544a67
https://doi.org/10.1158/1078-0432.22465380
https://doi.org/10.1158/1078-0432.22465380
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Purpose: Multiplex genomic profiling is standard of care for patients with advanced lung adenocarcinomas. The Lung Cancer Mutation Consortium (LCMC) is a multi-institutional effort to identify and treat oncogenic driver events in patients with lung a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1913afb2e23158b562d64cb46a58133d
https://doi.org/10.1158/1078-0432.c.6526008
https://doi.org/10.1158/1078-0432.c.6526008
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplemental Table 5. All subjects with all molecular results in LCMC2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510d07c813f59adc1fe62d88707da624
https://doi.org/10.1158/1078-0432.22465386.v1
https://doi.org/10.1158/1078-0432.22465386.v1
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
PTEN and MET IHC methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed2b0ba3a44a08ad88e28fba74a6786
https://doi.org/10.1158/1078-0432.22465389.v1
https://doi.org/10.1158/1078-0432.22465389.v1
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplemental Table 6. TP53 mutations seen in subjects in LCMC2, and categorization as disruptive or nondisruptive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd53f5eecc79e6f2656edbfcd526c0d8
https://doi.org/10.1158/1078-0432.22465383.v1
https://doi.org/10.1158/1078-0432.22465383.v1
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116972797f9029dc2acac18fc8bc613d
https://doi.org/10.1158/1078-0432.22465395.v1
https://doi.org/10.1158/1078-0432.22465395.v1
Autor:
David J. Kwiatkowski, Paul A. Bunn, Mark G. Kris, John D. Minna, Bruce E. Johnson, Ignacio I. Wistuba, Kelly Kugler, Yu Shyr, Julie Brahmer, Lecia V. Sequist, Saiama N. Waqar, Joan Schiller, Edward B. Garon, Jeremy Cetnar, Bonnie Glisson, Katerina Politi, Eric Haura, Gregory A. Otterson, Liza C. Villaruz, Suresh S. Ramalingam, Andre L. Moreira, Junya Fujimoto, Heidi Chen, Michael R. Rossi, Lynne D. Berry, Lynette M. Sholl, Dara L. Aisner
Supplementary Figure 1 Sample Analysis Flowchart Supplementary Figure 2 LOMC2 Gene List Supplementary Figure 3 PTEN Immunohistochemistry analysis of LCMC II samples. Supplementary Figure 4 Mutation Frequency by Mutation and Smoking Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9542dbd789701132715771c82d9941c6
https://doi.org/10.1158/1078-0432.22465392
https://doi.org/10.1158/1078-0432.22465392
Autor:
Farah Khalil, Mark G. Kris, Ignacio I. Wistuba, Theresa A. Boyle, Kelly Kugler, Paul A. Bunn, Gabriel Sica, Kim Ellison, Liping Zhang, Christopher J. Rivard, Lynette M. Sholl, Fred R. Hirsch, Mari Mino-Kenudson, Eric B. Haura, Marileila Varella-Garcia, David J. Kwiatkowski, Andre L. Moreira, Heidi Chen, Lynne D. Berry, Junya Fujimoto, Mirna Z Knight, James Saller
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Introduction Overexpression of the mesenchymal-epithelial transition (MET) receptor, a receptor tyrosine kinase, can propel the growth of cancer cells and portends poor prognoses for patients with lung cancer. Evaluation of MET by immunohistochemistr
Autor:
Saiama N. Waqar, Andre L. Moreira, Gregory A. Otterson, Katerina Politi, Joan H. Schiller, Ignacio I. Wistuba, John D. Minna, Heidi Chen, Liza C. Villaruz, Eric B. Haura, Michael R. Rossi, Yu Shyr, Lynette M. Sholl, Dara L. Aisner, Mark G. Kris, Paul A. Bunn, David J. Kwiatkowski, Julie R. Brahmer, Kelly Kugler, Junya Fujimoto, Jeremy Cetnar, Bonnie S. Glisson, Lynne D. Berry, Lecia V. Sequist, Suresh S. Ramalingam, Bruce E. Johnson, Edward B. Garon
Purpose: Multiplex genomic profiling is standard of care for patients with advanced lung adenocarcinomas. The Lung Cancer Mutation Consortium (LCMC) is a multi-institutional effort to identify and treat oncogenic driver events in patients with lung a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e079c9bd44a55b80572f060b8dee6f
https://europepmc.org/articles/PMC7008001/
https://europepmc.org/articles/PMC7008001/