Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kelly Kaiser Walters"'
Autor:
Larry E. Morrison, Mary J. Fidler, Lela Buckingham, Susan Jewell, Sanjib Basu, Coon J th, Kelly Kaiser Walters, Kristine Jacobson, Philip Bonomi, Marta Batus
Publikováno v:
British Journal of Cancer
Background: Preclinical studies in non-small cell lung cancer (NSCLC) suggest the interaction of PTEN and PI3K affects sensitivity to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). We investigated outcomes in relation to P
Autor:
Jing Du, Lela Buckingham, Kelly Kaiser Walters, Ekaterina Pestova, William Barbanera, Thomas A. Hensing, Philip Bonomi, Ying Zhang, Mary J. Fidler
Publikováno v:
Journal of Clinical Oncology. 32:e22043-e22043
e22043 Background: Loss of PTEN and gain of PIK3CA have been postulated as downstream mechanisms of resistance to anti-EGFR therapy in NSCLC. Clinical data suggests use of EGFR tyroisine kinase inh...
Autor:
Mary J. Fidler, Sanjib Basu, Kelly Kaiser Walters, Philip Bonomi, Marta Batus, Mark Pool, Brett Mahon, Lela Buckingham, Thomas A. Hensing
Publikováno v:
Journal of Clinical Oncology. 31:e19113-e19113
e19113 Background: TTF-1 is a transcription factor involved in regulating epithelial to mesenchymal transition. TTF-1 has a favorable prognosis in early stage lung adenocarcinoma, although it’s prognostic value in erlotinib treated patients remains
Autor:
Kelly Kaiser Walters, Marta Batus, Mary J. Fidler, Sanjib Basu, Jeffrey A. Borgia, Brett Mahon, Mark Pool, Philip Bonomi, Thomas A. Hensing, Lela Buckingham
Publikováno v:
Journal of Clinical Oncology. 31:e19117-e19117
e19117 Background: An epithelial phenotype in NSCLC is associated with improved sensitivity to EGFR tyrosine kinase inhibitors (TKI). The best method to identify this subset is unknown (Richardson Anticancer Research 2012, Byers Clin Cancer Res 2012)
Autor:
Wen-Rong Lie, Jeffrey A. Borgia, Eduardo Braun, Sanjib Basu, Mary J. Fidler, Cristina Fhied, Reem Karmali, Philip Bonomi, Anjali Gangaram, Kelly Kaiser Walters
Publikováno v:
Journal of Clinical Oncology. 30:e21069-e21069
e21069 Background: BEV has produced modest benefits in patients (PTS) with advanced NSCLC. Identification of positive predictors for BEV would have important implications for individual PTS and health care costs. Methods: We performed a prospective e
Autor:
Marta Batus, Philip Bonomi, Thomas A. Hensing, Mark Pool, Brett Mahon, Jeffrey A. Borgia, Kelly Kaiser Walters, Manish J. Dave, Sanjib Basu, Diana Escarzaga, Mary J. Fidler
Publikováno v:
Journal of Clinical Oncology. 30:e18117-e18117
e18117 Background: TTF-1 is a transcription factor involved in regulating epithelial to mesenchymal transition (EMT). Previous work in a clinically enriched non-small cell lung cancer (NSCLC) population suggested low probability of an EGFR activating
Autor:
Sanjib Basu, Mary J. Fidler, Kelly Kaiser Walters, Marta Batus, Brett Mahon, David J. Sher, Philip Bonomi, Mark Pool, Jeffrey A. Borgia
Publikováno v:
Journal of Clinical Oncology. 30:7067-7067
7067 Background: Thoracic radiation and concurrent chemotherapy consisting of platinum based doublets has produced modest improvement in long term survival for patient with locally advanced (LA) NSCLC. There is relatively little information regarding
Autor:
Sanjib Basu, D. C. McFarland, Jeffrey A. Borgia, Lela Buckingham, Kelly Kaiser Walters, P. Bonomi, Marta Batus, John S. Coon, Mary J. Fidler
Publikováno v:
Journal of Clinical Oncology. 29:e21136-e21136
e21136 Background: Minimal advances have been made in the treatment of NECs, including small cell lung cancer (SCLC). Bcl-2 and Bax are key regulators of apoptosis. Previous studies have shown that...
Autor:
Sanjib Basu, O. Rouhi, Jeffrey A. Borgia, G. Olmsted, John S. Coon, I. Cela, Kelly Kaiser Walters, P. Bonomi, Mary J. Fidler, Reem Karmali
Publikováno v:
Journal of Clinical Oncology. 28:7553-7553
7553 Background: The insulin growth factor receptor-1 (IGFR-1) signaling pathway is implicated in the oncogenesis of NSCLC and resistance to epidermal growth factor tyrosine kinase inhibitors (EGFR...
Autor:
R. Myint, Mark Pool, Kelly Kaiser Walters, Marta Batus, John S. Coon, D. C. McFarland, P. Bonomi, Sanjib Basu, Mary J. Fidler
Publikováno v:
Journal of Clinical Oncology. 28:e21039-e21039
e21039 Background: Minimal advances have been made in treatment of NECs including small cell lung cancer (SCLC). Molecular markers may allow us to identify patients most likely to benefit from new ...