Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Kelly K. Nichols"'
Autor:
John D. Sheppard, Kelly K. Nichols
Publikováno v:
Ophthalmology and Therapy, Vol 12, Iss 3, Pp 1397-1418 (2023)
Abstract Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum secretion and/or a change in meibum composition that results in the disruption
Externí odkaz:
https://doaj.org/article/3a3026df0080465282cc234157a79e6a
Autor:
Jianzhong Chen, Kelly K. Nichols
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2223-2236 (2018)
The lipid composition of human meibomian gland secretions (meibum) has been analyzed using both targeted and untargeted mass spectrometric approaches, each of which has its advantages and disadvantages. Herein we report the results of shotgun lipidom
Externí odkaz:
https://doaj.org/article/28d22cecc03f4dc08901e50920485111
Autor:
Jianzhong Chen, Kelly K. Nichols
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 9, Pp 1640- (2019)
Externí odkaz:
https://doaj.org/article/63bcc978d9074edcbcce41e26a31d880
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3277 (2020)
The lipidomic analysis of immortalized human meibomian gland epithelial cells (HMGECs) has been proposed as a preclinical model to study meibomian gland dysfunction. An in vitro study was conducted to evaluate neutral lipid recovery following three h
Externí odkaz:
https://doaj.org/article/ebe348d29af14568a08b913715d98833
Autor:
Anat Galor, Alexis Ceecee Britten-Jones, Yun Feng, Giulio Ferrari, David Goldblum, Preeya K. Gupta, Jesus Merayo-Lloves, Kyung-Sun Na, Shehzad A. Naroo, Kelly K. Nichols, Eduardo M. Rocha, Louis Tong, Michael T.M. Wang, Jennifer P. Craig
Publikováno v:
The Ocular Surface. 28:262-303
Autor:
Marjan Farid, Brandon D Ayres, Eric Donnenfeld, Ian Benjamin Gaddie, Preeya K Gupta, Edward Holland, Richard Lindstrom, Stephen C Pflugfelder, Paul M Karpecki, Kelly K Nichols, Christopher E Starr, Elizabeth Yeu
Publikováno v:
Clinical Ophthalmology. 17:667-679
Marjan Farid,1 Brandon D Ayres,2 Eric Donnenfeld,3 Ian Benjamin Gaddie,4 Preeya K Gupta,5 Edward Holland,6 Richard Lindstrom,7 Stephen C Pflugfelder,8 Paul M Karpecki,9 Kelly K Nichols,10 Christopher E Starr,11 Elizabeth Yeu12 1Gavin Herbert Eye Inst
Autor:
Stephen C. Pflugfelder, Austin Cao, Anat Galor, Kelly K. Nichols, Noam A. Cohen, Michelle Dalton
Publikováno v:
The Ocular Surface. 25:58-64
Tear secretion is regulated by the lacrimal functional unit consisting of afferent and efferent nerve innervation. The afferent arm consists of trigeminal nociceptors on the ocular surface and nasal mucosa. When stimulated by agonists, nicotinic acet
Publikováno v:
Ophthalmology and Therapy. 11:1449-1461
This clinical trial assessed the activity of reproxalap, a novel reactive aldehyde species modulator, and estimated clinically relevant thresholds for changes in ocular itching and redness in an allergic conjunctivitis field trial.This was a randomiz
Autor:
Brandon D. Ayres, Eric Donnenfeld, Marjan Farid, Ian Benjamin Gaddie, Preeya K. Gupta, Edward Holland, Paul M. Karpecki, Richard Lindstrom, Kelly K. Nichols, Stephen C. Pflugfelder, Christopher E. Starr, Elizabeth Yeu
Publikováno v:
Eye.
Background Twelve ocular surface disease experts convened to achieve consensus about Demodex blepharitis (DB) using a modified Delphi panel process. Methods Online surveys were administered using scaled, open-ended, true/false, and multiple-choice qu