Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Kelly K. Curtis"'
Autor:
Daniel W. Bowles, Lee S. Rosen, Sally Stewart, Esha Gangolli, Helene Faessel, James Partyka, Asit Parikh, Lori J. Wirth, David P. Ryan, Emiliano Calvo, Manuel Hidalgo, Kelly K. Curtis, Mitesh J. Borad, S. Gail Eckhardt, Jonathan Goldman
Purpose: This first-in-human study assessed safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of single and multiple doses of TAK-441, an investigational inhibitor of the Hedgehog signaling pathway.Experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ed283095ab91fa4ee3afefd8ca2e83
https://doi.org/10.1158/1078-0432.c.6524709.v1
https://doi.org/10.1158/1078-0432.c.6524709.v1
Autor:
Daniel W. Bowles, Lee S. Rosen, Sally Stewart, Esha Gangolli, Helene Faessel, James Partyka, Asit Parikh, Lori J. Wirth, David P. Ryan, Emiliano Calvo, Manuel Hidalgo, Kelly K. Curtis, Mitesh J. Borad, S. Gail Eckhardt, Jonathan Goldman
Supplementary Table S1. On-study patient deaths
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526ccbc800bd8c946f6663bbf436cfc6
https://doi.org/10.1158/1078-0432.22461177
https://doi.org/10.1158/1078-0432.22461177
Autor:
Alexander I. Spira, Bella Ertik, Zhonggai Li, Aaron R. Hansen, Wael A. Harb, Makoto Origuchi, Walid L. Shaib, Erina Koga-Yamakawa, Kelly K. Curtis
Publikováno v:
Targeted Oncology
Background Wilms’ tumor 1 (WT1) is overexpressed in various malignancies. DSP-7888 Dosing Emulsion, also known as ombipepimut-S (United States Adopted Name; International Nonproprietary Name: adegramotide/nelatimotide), is an investigational therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c59efe58e2c1aa215a6f0fcb38f4a6
https://doi.org/10.1007/s11523-021-00813-6
https://doi.org/10.1007/s11523-021-00813-6
Publikováno v:
Journal of Cancer, Vol 3, Iss 1, Pp 345-353 (2012)
Concomitant medication (CM) use may result in Phase I cancer clinical trial ineligibility due to concern for potential CM-investigational drug interactions or alteration of investigational drug absorption. Few studies have examined the impact of CM u
Externí odkaz:
https://doaj.org/article/27939b66a8d04a6d87ae46836411b520
Autor:
Michele Y. Halyard, Kelly K. Curtis, Devyani Lal, Mauricio E. Gamez, Carlos Vargas, Samir H. Patel, William W. Wong, Robert L. Foote, Stephen J. Ko
Publikováno v:
Head & Neck. 39:1819-1824
Background Sinonasal undifferentiated carcinoma (SNUC) is a rare aggressive disease arising in the nasal cavity and paranasal sinuses with poor prognosis and unclear optimal management. Methods Forty patients were analyzed. Nasal cavity was the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc51049f1dc83194c230a2635e30344
https://doi.org/10.1002/hed.24834
https://doi.org/10.1002/hed.24834
Autor:
Michael L. Hinni, Michele Y. Halyard, Thomas H. Nagel, Carlos Vargas, William W. Wong, Mauricio E. Gamez, Daniel J. Ma, Matthew A. Zarka, Samir H. Patel, Richard E. Hayden, Kelly K. Curtis
Publikováno v:
Annals of Otology, Rhinology & Laryngology. 126:185-191
Purpose: To report the outcomes of patients with favorable risk oropharyngeal cancer that underwent adjuvant radiation therapy with omission of the primary site from the clinical target volume (CTV). Material/Methods: A retrospective study of 40 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dad95e362e803aea107a0e5d71f5acf
https://doi.org/10.1177/0003489416681580
https://doi.org/10.1177/0003489416681580
Autor:
Vasily Andrianov, Keren Rachel Moss, Laura Vidal, Anthony J Messina, Liat Vidal, Kelly K. Curtis
Publikováno v:
Blood. 136:10-11
Introduction: Patient-reported outcomes (PRO) provide meaningful insight into patient perspectives on treatment effect. Clinically relevant outcomes such as improvements in overall survival (OS) and quality of life (QOL) should guide clinical decisio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2324f485f388d8d73d83f9d359b46a31
https://doi.org/10.1182/blood-2020-140318
https://doi.org/10.1182/blood-2020-140318
Autor:
Kelly K. Curtis, Ashley L. Garrett
Publikováno v:
Mayo Clinic Proceedings. 90:e129-e133
50-year-old postmenopausal woman with a history of hypothyroidism and obesity presented to her primary care physician with a several-month history of fatigue. On evaluation, she had no history of fever, chills, night sweats, weight change, abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7da5fc2f4a3446bd99098b247b2738c
https://doi.org/10.1016/j.mayocp.2015.05.023
https://doi.org/10.1016/j.mayocp.2015.05.023
Autor:
Kelly K. Curtis, S. Gail Eckhardt, Emiliano Calvo, Lee S. Rosen, Esha Gangolli, Asit Parikh, Daniel W. Bowles, Manuel Hidalgo, Lori J. Wirth, Sally Stewart, Jonathan H. Goldman, Hélène M. Faessel, David P. Ryan, Mitesh J. Borad, James Partyka
Publikováno v:
Clinical Cancer Research. 21:1002-1009
Purpose: This first-in-human study assessed safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of single and multiple doses of TAK-441, an investigational inhibitor of the Hedgehog signaling pathway. Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08a43ff4a1b49ea7c756a67d12a2194
https://doi.org/10.1158/1078-0432.ccr-14-1234
https://doi.org/10.1158/1078-0432.ccr-14-1234
Autor:
Konstantinos N. Lazaridis, Ryan M. Carr, Amulya A. Nageswara Rao, Gavin R. Oliver, Karl J. Clark, Stephen M. Ansell, Eriko Iguchi, Thorvardur R. Halfdanarson, Robert R. McWilliams, Heidi D. Finnes, Animesh Pardanani, Sarah E. Kerr, Tara L. Hogenson, Jean Pierre A. Kocher, Ramesh K. Ramanathan, Mitesh J. Borad, Richard W. Joseph, Aryan Ala'Aldeen, Steven I. Robinson, Aaron S. Mansfield, Ronald S. Go, Raoul Tibes, Colleen M. Tagtow, Chelsea D. Gawryletz, Eric D. Wieben, Anne M. Vrabel, Naresh Prodduturi, Alvin C. Silva, Grzegorz S. Nowakowski, David W. Mead, Aminah Jatoi, Prashant Kapoor, Tammy M. McAllister, Elisa Enriquez Hesles, Luciana L. Almada, Eric W. Klee, Eileen J. Kennedy, David L. Marks, John C. Cheville, Sikander Ailawadhi, Asif Hossain, Kandelaria M. Rumilla, Mrinal M. Patnaik, Stephanie L. Safgren, Ernesto Resnik, Jan B. Egan, Estrella M. Carballido, Asher Chanan-Khan, Martin E. Fernandez-Zapico, Paola A. Romecin-Duran, Thai H. Ho, Andrew L. Feldman, Norine E. Huneke, Nathalie Meurice, Kelly K. Curtis, Michaela S. Banck, Jennifer B. McCormick, Alan H. Bryce, Ashley N. Sigafoos, A. Keith Stewart, Sameer A. Parikh, Ezequiel J. Tolosa, Gianrico Farrugia
Publikováno v:
JCO precision oncology
Purpose Genomic testing has increased the quantity of information available to oncologists. Unfortunately, many identified sequence alterations are variants of unknown significance (VUSs), which thus limit the clinician’s ability to use these findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f17114dbda41b2e53e2e5e203520405
http://europepmc.org/articles/PMC6369924
http://europepmc.org/articles/PMC6369924