Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.

Autor: Carlos F Pereira, Rémi Terranova, Natalie K Ryan, Joana Santos, Kelly J Morris, Wei Cui, Matthias Merkenschlager, Amanda G Fisher

Publikováno v: PLoS Genetics, Vol 4, Iss 9, p e1000170 (2008)

Differentiated cells can be reprogrammed through the formation of heterokaryons and hybrid cells when fused with embryonic stem (ES) cells. Here, we provide evidence that conversion of human B-lymphocytes towards a multipotent state is initiated much

Externí odkaz: https://doaj.org/article/3d664c5a7ddc451eadf9eee78f820fe8

FANTOM5 CAGE profiles of human and mouse samples

Autor: Jun Kawai, Anthony G Beckhouse, Dipti Vijayan, Michael Rehli, Toshiyuki Nakamura, Yuki Hasegawa, Timothy C. Barnett, Hisashi Shimoji, Erik Arner, Masayoshi Itoh, Masahide Hamaguchi, Sarah Klein, Reto Guler, Patrizia Rizzu, Atsutaka Kubosaki, Soichi Kojima, Timo Lassmann, Kelly J. Morris, Mutsumi Kanamori-Katayama, Ri Ichiroh Manabe, Hiromasa Morikawa, Kelly J Hitchens, Fumi Hori, Linda M. van den Berg, Yasushi Okazaki, Andru Tomoiu, Antti Sajantila, Akiko Saka, Thierry Sengstag, Alessandro Bonetti, Haruhiko Koseki, Matthias Edinger, Mitsuhiro Ohshima, Carsten O. Daub, Jayson Harshbarger, Sachi Ishikawa-Kato, Tsugumi Kawashima, Christine L. Mummery, Niklas Mejhert, Jun Takai, Dan Goldowitz, Naoko Suzuki, Guojun Sheng, David A. Hume, Hiroshi Kawamoto, Ai Kaiho, Jun Ichi Furusawa, Ailsa J Carlisle, Tomokatsu Ikawa, Shiro Fukuda, Peter G. Zhang, Akira Hasegawa, James Briggs, Toshio Kitamura, Alistair R. R. Forrest, Takahiro Arakawa, Marcvande Wetering, Shohei Noma, Fumio Nakahara, Jessica Severin, Sven Guhl, Atsushi Kondo, Mary C. Farach-Carson, Hans Clevers, Afsaneh Eslami, Christian Schmidl, Peter Heutink, Hideki Tatsukawa, Anita Schwegmann, Noriko Ninomiya, Antje Blumenthal, Yoshihide Hayashizaki, Suzana Savvi, Thomas J. Ha, Claudio Schneider, Daisuke Sugiyama, Hironori Satoh, Mitsuru Morimoto, Hiroki Sato, Yosuke Mizuno, Meenhard Herlyn, Hozumi Motohashi, Shigehiro Yoshida, Hiroo Toyoda, Christophe Simon, Piero Carninci, Tadasuke Nozaki, Hideya Kawaji, Louise N. Winteringham, Swati Pradhan-Bhatt, Imad Abugessaisa, Michihira Tagami, Tony J. Kenna, Yoko Yamaguchi, Geoffrey J. Faulkner, Alka Saxena, Naoto Kondo, Dmitry A. Ovchinnikov, Rie Fujita, Ernst J. Wolvetang, Michael Detmar, Miki Kojima, Peter Arner, Mitsuko Hara, Stefano Gustincich, Carrie A. Davis, Judith S. Kempfle, Margaret Patrikakis, Alan Mackay-Sim, Carmelo Ferrai, Yutaka Nakachi, Juha Kere, Mitsuyoshi Murata, Shimon Sakaguchi, Soichi Ogishima, Silvia Zucchelli, Andreas Lennartsson, Thomas R. Gingeras, Masanori Suzuki, Beatrice Bodega, Sugata Roy, Sayaka Nagao-Sato, Mitsuhiro Endoh, Anna Ehrlund, J Kenneth Baillie, Mizuho Sakai, Michela Fagiolini, Taeko Dohi, Christine A. Wells, Frank Brombacher, Masayuki Yamamoto, Robert Passier, Lynsey Fairbairn, Teunis B. H. Geijtenbeek, Shigeo Koyasu, Hiromi Nishiyori-Sueki, Yuri Ishizu, Yuki I. Kawamura, Chiyo Yanagi-Mizuochi, Roberto Verardo, Misako Yoneda, Mariko Okada-Hatakeyama, Kaoru Kaida, Ana Pombo, Gundula Schulze-Tanzil, Lesley M. Forrester, Kim M. Summers, Harukazu Suzuki, Naganari Ohkura, Weon Ju Lee, Hiroshi Tanaka, Alan J. Knox, Karl Ekwall, Yukio Nakamura, Serkan Sahin, Shuhei Noguchi, Hiroshi Ohno, Yohei Yonekura, Richard A Axton, Marina Lizio, S. Peter Klinken, Malcolm E. Fisher, Shoko Watanabe, Magda Babina, Xian-Yang Qin, Takaaki Sugiyama, B. Albert S. Edge, Eri Saijyo, Valerio Orlando, Takeya Kasukawa, Kazuyo Moro, Kenichi Nakazato, Naoko Takahashi, Levon M. Khachigian, Chieko Kai, Masaaki Furuno, Jay W. Shin, Hideki Enomoto

Publikováno v: Scientific Data
Scientific data 4(1), 170112 (2017). doi:10.1038/sdata.2017.112
Scientific data, 4. Nature Publishing Group
Scientific Data, 4
Noguchi, S, Arakawa, T, Fukuda, S, Furuno, M, Hasegawa, A, Hori, F, Ishikawa-Kato, S, Kaida, K, Kaiho, A, Kanamori-Katayama, M, Kawashima, T, Kojima, M, Kubosaki, A, Manabe, R-I, Murata, M, Nagao-Sato, S, Nakazato, K, Ninomiya, N, Nishiyori-Sueki, H, Noma, S, Saijyo, E, Saka, A, Sakai, M, Simon, C, Suzuki, N, Tagami, M, Watanabe, S, Yoshida, S, Arner, P, Axton, R A, Babina, M, Baillie, J K, Barnett, T C, Beckhouse, A G, Blumenthal, A, Bodega, B, Bonetti, A, Briggs, J, Brombacher, F, Carlisle, A J, Clevers, H C, Davis, C A, Detmar, M, Dohi, T, Edge, A S B, Edinger, M, Ehrlund, A, Ekwall, K, Endoh, M, Enomoto, H, Eslami, A, Fagiolini, M, Fairbairn, L, Farach-Carson, M C, Faulkner, G J, Ferrai, C, Fisher, M E, Forrester, L M, Fujita, R, Furusawa, J-I, Geijtenbeek, T B, Gingeras, T, Goldowitz, D, Guhl, S, Guler, R, Gustincich, S, Ha, T J, Hamaguchi, M, Hara, M, Hasegawa, Y, Herlyn, M, Heutink, P, Hitchens, K J, Hume, D A, Ikawa, T, Ishizu, Y, Kai, C, Kawamoto, H, Kawamura, Y I, Kempfle, J S, Kenna, T J, Kere, J, Khachigian, L M, Kitamura, T, Klein, S, Klinken, S P, Knox, A J, Kojima, S, Koseki, H, Koyasu, S, Lee, W, Lennartsson, A, Mackay-Sim, A, Mejhert, N, Mizuno, Y, Morikawa, H, Morimoto, M, Moro, K, Morris, K J, Motohashi, H, Mummery, C L, Nakachi, Y, Nakahara, F, Nakamura, T, Nakamura, Y, Nozaki, T, Ogishima, S, Ohkura, N, Ohno, H, Ohshima, M, Okada-Hatakeyama, M, Okazaki, Y, Orlando, V, Ovchinnikov, D A, Passier, R, Patrikakis, M, Pombo, A, Pradhan-Bhatt, S, Qin, X-Y, Rehli, M, Rizzu, P, Roy, S, Sajantila, A, Sakaguchi, S, Sato, H, Satoh, H, Savvi, S, Saxena, A, Schmidl, C, Schneider, C, Schulze-Tanzil, G G, Schwegmann, A, Sheng, G, Shin, J W, Sugiyama, D, Sugiyama, T, Summers, K M, Takahashi, N, Takai, J, Tanaka, H, Tatsukawa, H, Tomoiu, A, Toyoda, H, van de Wetering, M, van den Berg, L M, Verardo, R, Vijayan, D, Wells, C A, Winteringham, L N, Wolvetang, E, Yamaguchi, Y, Yamamoto, M, Yanagi-Mizuochi, C, Yoneda, M, Yonekura, Y, Zhang, P G, Zucchelli, S, Abugessaisa, I, Arner, E, Harshbarger, J, Kondo, A, Lassmann, T, Lizio, M, Sahin, S, Sengstag, T, Severin, J, Shimoji, H, Suzuki, M, Suzuki, H, Kawai, J, Kondo, N, Itoh, M, Daub, C O, Kasukawa, T, Kawaji, H, Carninci, P, Forrest, A R R & Hayashizaki, Y 2017, ' FANTOM5 CAGE profiles of human and mouse samples ', Scientific Data, vol. 4, 170112 . https://doi.org/10.1038/sdata.2017.112

Scientific Data, 4
ISSN:2052-4463

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076c9afc5abce3ac80b1dc4baa06a13d

Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment

Autor: Kelly J. Morris, Alan G. Ramsay, Andrew Clear, Maria Calaminici, Finlay MacDougall, Abigail M. Lee, Gavin Kelly, T. Andrew Lister, John G. Gribben, Simon Hallam

Publikováno v: Blood. 115:5053-5056

Follicular lymphoma has considerable clinical heterogeneity, and there is a need for easily quantifiable prognostic biomarkers. Microvessel density has been shown to be a useful prognostic factor based on numerical assessment of vessel numbers within

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f311b05f359d404d22cea38864e589
https://doi.org/10.1182/blood-2009-11-253260

Nuclear Architecture in Stem Cells

Autor: Kelly J. Morris, Ana Pombo, Mita Chotalia

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781441970367

Fundamental features of genome regulation depend on the linear DNA sequence, cell type specific modification of DNA and chromatin-associated proteins, which locally control the expression of single genes. Architectural features of genome organization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f01f47236bda2eea4a19140ed0efee6
https://doi.org/10.1007/978-1-4419-7037-4_2

SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL

Autor: Andrew Clear, Roberto Passetto Falcão, Wilson A. Silva, John G. Gribben, Marco Antônio Zago, Francisco de Paula Careta, Carolyn Owen, Rodrigo Alexandre Panepucci, Kelly J. Morris, Rodrigo Proto-Siqueira, Edgar Gil Rizzatti, Abigail M. Lee

To identify novel genes involved in the molecular pathogenesis of chronic lymphocytic leukemia (CLL) we performed a serial analysis of gene expression (SAGE) in CLL cells, and compared this with healthy B cells (nCD19+). We found a high level of simi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c9e96e60ffd5ac848dd10a159d6b99
https://europepmc.org/articles/PMC2442748/