Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kelly J. McKelvey"'
Autor:
Kelly J. McKelvey, Amanda L. Hudson, Heather Donaghy, Shihani P. Stoner, Helen R. Wheeler, Connie I. Diakos, Viive M. Howell
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background Radiotherapy (RT) is a mainstay of treatment for patients with glioblastoma (GB). Early clinical trials show that short course hypofractionation showed no survival benefit compared to conventional regimens with or without temozolo
Externí odkaz:
https://doaj.org/article/56a73af82ee04918a6c8248c8a15a583
Autor:
Gaayathri Ariyakumar, Jonathan M. Morris, Kelly J. McKelvey, Anthony W. Ashton, Sharon A. McCracken
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Intrauterine Growth Restriction (IUGR) is a leading cause of perinatal death with no effective cure, affecting 5–10% pregnancies globally. Suppressed pro-inflammatory Th1/Th17 immunity is necessary for pregnancy success. However, in IUGR,
Externí odkaz:
https://doaj.org/article/66e2437b19f747e09ed637c496af47d2
Autor:
Takanori Hioki, Yaser H. Gholami, Kelly J. McKelvey, Alireza Aslani, Harry Marquis, Enid M. Eslick, Kathy P. Willowson, Viive M. Howell, Dale L. Bailey
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Positron (β+) emitting radionuclides have been used for positron emission tomography (PET) imaging in diagnostic medicine since its development in the 1950s. Development of a fluorinated glucose analog, fluorodeoxyglucose, labelled with a
Externí odkaz:
https://doaj.org/article/ea60cf303261425688fef7141cb44b96
Autor:
Wei Deng, Kelly J. McKelvey, Anna Guller, Alexey Fayzullin, Jared M. Campbell, Sandhya Clement, Abbas Habibalahi, Zofia Wargocka, Liuen Liang, Chao Shen, Viive Maarika Howell, Alexander Frank Engel, Ewa M. Goldys
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 715-726 (2020)
Externí odkaz:
https://doaj.org/article/9c667638a9b04b079bd935da8cad2ac2
Autor:
Kelly J. McKelvey, Erica B. Wilson, Susan Short, Alan A. Melcher, Michael Biggs, Connie I. Diakos, Viive M. Howell
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) is the most aggressive adult glioma with a median survival of 14 months. While standard treatments (safe maximal resection, radiation, and temozolomide chemotherapy) have increased the median survival in favorable O(6)-methylguanin
Externí odkaz:
https://doaj.org/article/030135989f354254a2b6784b5c9da99f
Autor:
Kelly J. McKelvey, Amanda L. Hudson, Ramyashree Prasanna Kumar, Thomas Eade, Stephen J. Clarke, Helen R. Wheeler, Connie I. Diakos, Viive M. Howell
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Brain, lung, and colon tissue experience deleterious immune-related adverse events when immune-oncological agents or radiation are administered. However, there is a paucity of information regarding whether the addition of radiation to immuno-oncologi
Externí odkaz:
https://doaj.org/article/b0ce4e12c6224fa2a7b1602d3d9d9d8b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7265 (2021)
As the cornerstone of high-grade glioma (HGG) treatment, radiotherapy temporarily controls tumor cells via inducing oxidative stress and subsequent DNA breaks. However, almost all HGGs recur within months. Therefore, it is important to understand the
Externí odkaz:
https://doaj.org/article/98d6f50cbbc544c297130d7aadad5cb3
Autor:
Kelly J. McKelvey, Katie L. Powell, Anthony W. Ashton, Jonathan M. Morris, Sharon A. McCracken
Publikováno v:
Journal of Circulating Biomarkers, Vol 4 (2015)
Exosomes are 30–100 nm microvesicles which contain complex cellular signals of RNA, protein and lipids. Because of this, exosomes are implicated as having limitless therapeutic potential for the treatment of cancer, pregnancy complications, infecti
Externí odkaz:
https://doaj.org/article/3620402ed5234f3689116cb5639630c1
Autor:
Grace Lim, Alexander Widiapradja, Scott P Levick, Kelly J McKelvey, Xiao-Hui Liao, Samuel Refetoff, Martyn Bullock, Roderick J Clifton-Bligh
Publikováno v:
Endocrinology. 163(12)
Context Foxe1 is a key thyroid developmental transcription factor. Germline deletion results in athyreosis and congenital hypothyroidism. Some data suggest an ongoing role for maintaining thyroid differentiation. Objective We created a mouse model to
Autor:
Kelly J. McKelvey, Christopher J. Jackson, Fang Wang, Suat Dervish, Christopher B. Little, Lyn March, Meilang Xue
Publikováno v:
Rheumatology. 58:1850-1860
ObjectivesTo investigate whether activated protein C (APC), a physiological anticoagulant can inhibit the inflammatory/invasive properties of immune cells and rheumatoid arthritis synovial fibroblasts (RASFs) in vitro and prevent inflammatory arthrit