Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kelly J. Dix"'
Autor:
Daniel J. Kramer, Ling-Jen Chen, J. Michael Sanders, Leslie A. Thomas, Jacob D. McDonald, Christopher J. Wegerski, Kelly J. Dix
Publikováno v:
Drug Metabolism and Disposition. 39:498-509
Cumene is a high-production volume chemical that has been shown to be a central nervous system depressant and has been implicated as a long-term exposure carcinogen in experimental animals. The absorption, distribution, metabolism, and excretion of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb609aa38b84812e6a4a9440fa815a0
https://doi.org/10.1124/dmd.110.034769
https://doi.org/10.1124/dmd.110.034769
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 70:781-788
The metabolism of orally administered N,N-dimethyl-p-toluidine (DMPT) in male F344 rats was investigated. The rat urinary metabolite profile was determined by analytical reverse-phase high performance liquid chromatography (HPLC). Four radiolabeled p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899c3c730103982c11dd45bbe17d03e4
https://doi.org/10.1080/15287390701206176
https://doi.org/10.1080/15287390701206176
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 70:789-798
N,N-Dimethyl-p-toluidine (DMPT) is used as a polymerization accelerator, in industrial glues, and as an intermediate in dye and pesticide synthesis. There is potential for human exposure to DMPT. The disposition of oral and intravenous (i.v.) doses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b536ae55bbb11a0f0b6095323b6d58
https://doi.org/10.1080/15287390701206291
https://doi.org/10.1080/15287390701206291
Autor:
Jacob D. McDonald, Kelly J. Dix, Dean Kracko, Rogene F. Henderson, Katayoon Ghanbari, Mark Gurule, Briana M. Hedtke-Weber
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 70:582-593
The disposition of [14C]methyltetrahydrofuran (14C-MTHF) in rats and mice was determined by following changes in the radioactivity in tissue and excreta with time after dosing. MTHF administered orally (1, 10, or 100 mg/kg) or intravenously (1 mg/kg)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88777e596d6b29dff19c982bc225104
https://doi.org/10.1080/10937400600882848
https://doi.org/10.1080/10937400600882848
Autor:
Dolores C. Esparza, Jacob D. McDonald, Kelly J. Dix, Thomas H. March, Patricia Y Cossey, Larry E. Bowen
Publikováno v:
Experimental Lung Research. 30:383-404
A past study demonstrated that all-trans-retinoic acid (ATRA) treatment by intraperitoneal injection in a rat model of elastase-induced emphysema caused tissue regeneration as evidenced by a decrease in alveolar size and lung volume and an increase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473715bb5a9852eb92098889d670ef29
https://doi.org/10.1080/01902140490463142
https://doi.org/10.1080/01902140490463142
Autor:
James A. Crowell, Marjorie G Busby, A. Robert Jeffcoat, Brian F. Thomas, Tracy M. Black, Craig P. Albright, Wlodek Lopaczynski, Michael J. Schell, LeAnne T Bloedon, Steven H. Zeisel, Kelly J. Dix
Publikováno v:
The American Journal of Clinical Nutrition. 76:1126-1137
Background: Soy isoflavones are being evaluated as chemopreventive agents for breast and other cancers. Objective: The objective was to perform safety and pharmacokinetic studies of purified unconjugated isoflavone preparations containing genistein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc171c7ecade8f9531cdab7c1488540
https://doi.org/10.1093/ajcn/76.5.1126
https://doi.org/10.1093/ajcn/76.5.1126
Autor:
Kelly J. Dix, Matthew A. Koch, Judith Hill, James A. Crowell, Tracy M. Black, LeAnne T Bloedon, Brian F. Thomas, William D. Heizer, Steven H. Zeisel, Marjorie G Busby, A. Robert Jeffcoat
Publikováno v:
The American Journal of Clinical Nutrition. 75:126-136
Background: Soy isoflavones are potential cancer chemoprevention treatments. Objective: We conducted safety studies of purified unconjugated genistein, daidzein, and glycitein, and defined pharmacokinetic parameters for their absorption and metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fadf8ae997a4435b904a480a3eeeee7
https://doi.org/10.1093/ajcn/75.1.126
https://doi.org/10.1093/ajcn/75.1.126
Autor:
Leanne T Bloeden, Nicole M. Scheffler, Rene’ A Mitchell, A. Robert Jeffcoat, Kelly J. Dix, Sherri S. Brown, Marjory G Busby, Judith Hill, Steven H. Zeisel, Brian F. Thomas
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 760:191-205
Soy isoflavones are becoming of increasing interest as nutritional agents which can be used to combat osteoporosis and hyperlipidemia, and are also being considered as potential cancer chemopreventive compounds. However, prior to their formulation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726d9acf4b17c32e5321aaca62488b1d
https://doi.org/10.1016/s0378-4347(01)00269-9
https://doi.org/10.1016/s0378-4347(01)00269-9
Autor:
Heather Conway, Henry G Wall, Jacob D. McDonald, Matthew D. Reed, Ronald K. Wolff, Kelly J. Dix, Rodney A. Miller
Publikováno v:
Inhalation toxicology. 25(13)
Nebulized gentamicin solution was administered to rats (nose-only) and dogs (face mask) for 14 days with a 14-day recovery period. Control groups of each were exposed to saline aerosols. Mean estimated inhaled lung doses of gentamicin were 39, 123 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5810f83a07157d1bc42c4c6934fbf03
https://pubmed.ncbi.nlm.nih.gov/24255949
https://pubmed.ncbi.nlm.nih.gov/24255949
Autor:
Husein Ajwa, Iris S. Ale, Sandra L. Allen, Judith Alsop, Gail Arce, D.J. Ashworth, Sharada Balakrishnan, John B. Barnett, Dana B. Barr, Terrell Barry, Ronald E. Baynes, Sheryl Beauvais, Karin S. Bentley, Craig E. Bernard, Nida Besbelli, Richard Billington, Ann M. Blacker, Jerry N. Blancazo, Charles B. Breckenridge, Gerald T. Brooks, James Bruckner, Kathleen M. Brundage, Quang Bui, Franca M. Buratti, James S. Bus, Geoffrey M. Calvert, Linda L. Carlock, John E. Casida, Howard W. Chambers, Janice E. Chambers, Heidi P. Chan, Graham Chester, J. Marshall Clark, Thomas Class, M. Scott Clifton, Roger Cochran, Emma Di Consiglio, Curtis C. Dary, Franck E. Dayan, Allison L. De Vries, Kelly J. Dix, Michael H. Dong, Timothy A. Dotson, John Doull, Jeffrey H. Driver, Stephen O. Duke, M. Bigelow Dyk, David A. Eastmond, David L. Eaton, Marion Ehrich, David L. Eisenbrandt, J. Charles Eldridge, Jeffrey B. Evans, Donna Farmer, Allan S. Felsot, Penelope A. Fenner-Crisp, Joan L. Fletcher, Sara Flores, Roy Fortmann, Toshio Fujita, Derek W. Gammon, Suduan Gao, V.F. Garry, Sean C. Gehen, Panos Georgopoulos, B.B. Gollapudi, Elliot B. Gordon, F. Guerino, Thomas R. Hanley, Lindsay Hanson, Paul R. Harp, Michael C. Harrass, Jane E. Harris, Wayland J. Hayes, Thomas Hertner, Frederick G. Hess, William F. Heydens, Ernest Hodgson, L. Holden, Jon A. Hotchkiss, Susan Hurt, Sastry Isukapalli, Seshadri Iyengar, Poorni Iyer, Inge M. Jensen, Russell L. Jones, Bernard S. Jortner, Hideo Kaneko, Robert J. Kavlock, Iain D. Kelly, Michael P. Kenna, Elke Kennepohl, Young Soo Keum, Jeong-Han Kim, Loreen Kleinschmidt, Dennis R. Klonne, James B. Knaak, Mike E. Krolski, Ian C. Lamb, Richard L. Lampman, Mikael Langner, Jennifer L. Lantz, Dominique Lasserre-Bigot, Edward D. Levin, Qing X. Li, Jing Liu, Edward A Lock, Marcello Lotti, Curt Lunchick, A.V. Lyubimov, Howard Maibach, Lisa E. Maier, Susan Makris, Mark J. Manning, Rex E. Marsh, Melanie Marty, Ursula May-Hertl, Thomas McCurdy, Tom McKone, Edward C. Meek, Louise N. Mehler, Gary J. Mihlan, Thomas B. Moore, Marsha K. Morgan, Ian C. Munro, Toshio Narahashi, Keiichiro Nishimura, Robert J. Novak, William J. Ntow, Michael A. O’Malley, Frederick W. Oehme, Janet Ollinger, Thomas G. Osimitz, Muhilan D. Pandian, P.P. Parsons, Merle G. Paule, Virginie Payraudeau, Erin C. Peck, Alain F. Pelfrène, Kimberly Pendino, Barbara J. Petersen, Amanda L. Piccirillo, Vincent J. Piccirillo, Joachim D. Pleil, Kathryn Ponnock, Carey Pope, Robert H. Poppenga, Su-wei Qi, Ruijun Qin, Deborah Ramsingh, Lawrence W. Reiter, Rudy J. Richardson, Leonard Ritter, Jim E. Riviere, John H. Ross, Karl K. Rozman, Andrew L. Rubin, Michael K. Rust, Luis O. Ruzo, Terrell P. Salmon, G.K. (Ghona) Sangha, James N. Seiber, Frank Selman, Larry P. Sheets, Linda S. Sheldon, Marilyn Silva, James W. Simpkins, William Slikker, Paul Slovic, Andrew G. Smith, Wayne R. Snodgrass, Jon R. Sobus, David M. Soderlund, Keith R. Solomon, Frank Spurlock, James T. Stevens, Tammy E. Stoker, W.T. Stott, Daniel L. Sudakin, Chiyozo Takayama, Emanuela Testai, Thomas Thongsinthusak, Charles Timchalk, Olga A. Timofeeva, Abraham J. Tobia, Rogelio Tornero-Velez, Nicolle S. Tulve, Matazaemon Uchida, István Ujváry, Daniel Vallero, Bennard van Ravenswaay, Felix Waechter, Edgar Weber, Ronald C. Wester, Paul Whatling, Gary K. Whitmyre, Heinrich Wicke, Sanjeeva J. Wijeyesakere, Martin F. Wilks, Alan G.E. Wilson, Barry W. Wilson, Michael D. Woodward, Jayne Wright, S.R. Yates, Masanori Yoshida, Bruce M. Young, Frank G. Zalom, Valerie Zartarian, Hongbo Zhai, Xiaofei Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a870b5ec229c808850c63447b71171b2
https://doi.org/10.1016/b978-0-12-374367-1.00124-5
https://doi.org/10.1016/b978-0-12-374367-1.00124-5
