Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kelly J. Cain"'
Autor:
Stanley DeTurris, Richard Charboneau, Kelly J. Cain, Sabita Roy, Roderick A. Barke, Dean Melnyk
Publikováno v:
Surgery. 126:239-247
Background: Interleukin 12 (IL-12) p70 is a heterodimeric protein (p35, p40 subunits) that promotes T-helper TH1-type cytokine response. In critically ill patients, after severe trauma or sepsis, IL-12 production is markedly impaired. We tested the h
Autor:
Stanley DeTurris, Linda F. Carson, Kelly J. Cain, Roderick A. Barke, S Ramakrishin, Richard Charboneau, Sabita Roy
Publikováno v:
Journal of Surgical Research. 75:97-102
Animal models of stress and sepsis demonstrate increased hypophyseal gene expression of the transcription factor c-fos and the cytokines interleukin-1 and interleukin-6. Chronic central nervous system exposure to interleukin-1 results in hypermetabol
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374398
The idea that exogenous opiates can affect immune function is not entirely new. Historically as early as 1889 the effect of opium on leukocyte phagocytosis was described in a guinea pig model (1). More recently, evidence supporting the role of opiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8e1a1c2636850ded6c7fce17bfe7a9a
https://doi.org/10.1007/978-1-4615-5347-2_3
https://doi.org/10.1007/978-1-4615-5347-2_3
Autor:
Richard Charboneau, Rebecca B. Chapin, Roderick A. Barke, Sabita Roy, Sundaram Ramakrishnan, Kelly J. Cain
Publikováno v:
Cellular immunology. 179(1)
Chronic treatment of mice with morphine affects the proliferation, differentiation, and function of immune cells. In the present study, we investigated the mechanism by which morphine inhibits phytohemagglutinin (PHA)/interleukin-1 (IL-1)-induced thy
Publikováno v:
Archives of surgery (Chicago, Ill. : 1960). 130(11)
Objective: To investigate the hypothesis that a central dopaminergic mechanism may regulate hepatic c-fosand c-jungene expression following peritoneal sepsis. Methods: First, dopamine or vehicle was instilled into a stereotaxically placed intracerebr