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pro vyhledávání: '"Kelly Ivins-O'Keefe"'
Publikováno v:
Open Forum Infectious Diseases
Background Antibiotic pharmacokinetics (PK) differ between critically ill and noncritically ill patients, as do the bacteria causing infection, yet dosing regimens are derived from noncritically ill populations. The purpose of this study was to exami
Publikováno v:
Matrix Biology. 32:316-324
Thrombospondin-1 is a potent suppressor of T cell activation via its receptor CD47. However, the precise mechanism for this inhibition remains unclear. Because H2S is an endogenous potentiator of T cell activation and is necessary for full T cell act
Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47
Publikováno v:
Scientific Reports
Thrombospondin-1 regulates inflammation by engaging several cell surface receptors and by modulating activities of other secreted factors. We have uncovered a novel role of thrombospondin-1 in modulating production and activation of the proinflammato
Autor:
Kelly Ivins-O’Keefe, Kevin S. Akers
Publikováno v:
Open Forum Infectious Diseases. 3