Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kelly I. Guthrie"'
Autor:
Roger M. Ilagan, Kelly I. Guthrie, Sarah F. Quinlan, H. Scott Rapoport, Sarah Jones, Ashley Church, Joydeep Basu, John W. Ludlow
Publikováno v:
BioTechniques, Vol 48, Iss 2, Pp 153-155 (2010)
Three-dimensional collagen gel contraction is the standard assay utilized for functionally quantifying a variety of cell types, in particular smooth muscle cells (SMCs) and myofibroblasts. Here, we have developed a method to effectively reduce the th
Externí odkaz:
https://doaj.org/article/a7c26b60bbe64891a4b411c9fb9e3e30
Autor:
John Bianchi, Brandon L. Burger, Elizabeth C. Stahl, David Ayares, Whayoung Lee, Thomas Petersen, Bruce A. Bunnell, Ryan W. Bonvillain, Clint D. Skillen, Hidetaka Hara, Nicholas C. Pashos, Peter J. Didier, Kelly I. Guthrie, Cynthia B. Trygg, Brooke Grasperge, Bryan N. Brown
Publikováno v:
Biomaterials. 187
Whole organ tissue engineering is a promising approach to address organ shortages in many applications, including lung transplantation for patients with chronic pulmonary disease. Engineered lungs may be derived from animal sources after removing cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28e53148b3b85d4b2835210a84549e9
https://pubmed.ncbi.nlm.nih.gov/30312852
https://pubmed.ncbi.nlm.nih.gov/30312852
Autor:
Manuel J. Jayo, Elias A. Rivera, John W. Ludlow, Deepak Jain, Toyin Knight, Timothy A. Bertram, Kelly I. Guthrie, Richard G. Payne, Christopher W. Genheimer, Kim L. Mihalko, Joydeep Basu, Namrata Sangha
Publikováno v:
Medical Hypotheses. 78:231-234
Recent successes in regenerative medicine and tissue engineering of bladder and bladder-like neo-organs have leveraged regenerative constructs composed of a biodegradable scaffold seeded with a population of smooth muscle cells. We have shown that su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4aca380db529c1ba47f7969df217a60
https://doi.org/10.1016/j.mehy.2011.10.032
https://doi.org/10.1016/j.mehy.2011.10.032
Autor:
Joydeep Basu, Namrata Sangha, John W. Ludlow, Kelly I. Guthrie, Toyin Knight, Deepak Jain, Elias A. Rivera, Richard G. Payne, Timothy A. Bertram, Kim L. Mihalko, Christopher W. Genheimer, Manuel J. Jayo
Publikováno v:
Regenerative Medicine. 6:721-731
Aims: To apply an organ regeneration platform technology of autologous smooth muscle cell/biomaterial combination products, previously demonstrated to be successful for urinary tissue regeneration, to the regeneration of the small intestine. Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c33cd6e5b8b3315b13f547183de0208
https://doi.org/10.2217/rme.11.78
https://doi.org/10.2217/rme.11.78
Autor:
Belinda J. Wagner, Christopher W. Genheimer, Eric S. Werdin, John W. Ludlow, Elias A. Rivera, Andrew T. Bruce, Bryan R. Cox, Timothy A. Bertram, Kelly I. Guthrie, Patricia Tatsumi-Ficht, Russell W. Kelley, Roger M. Ilagan, Shay M. Wallace, Manuel J. Jayo, Sumana Choudhury, Sharon C. Presnell
Publikováno v:
Tissue Engineering Part C: Methods. 17:261-273
Chronic kidney disease (CKD) is a global health problem; the growing gap between the number of patients awaiting transplant and organs actually transplanted highlights the need for new treatments to restore renal function. Regenerative medicine is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477aebdf7dcd7c35df6faa6084dfac46
https://doi.org/10.1089/ten.tec.2010.0399
https://doi.org/10.1089/ten.tec.2010.0399
Autor:
Sarah F. Quinlan, John W. Ludlow, Jacob E. Shokes, Roger M. Ilagan, Chistopher W. Genheimer, Kelly I. Guthrie, Teresa Burnette, Andrew T. Bruce, Namrata Sangha, Joydeep Basu
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 19:184-189
Bladder tissue has been regenerated in humans with neurogenic bladder using an implant produced from autologous urothelial (UC) and smooth muscle cells (SMC) expanded from bladder biopsies seeded onto a biodegradable synthetic scaffold. As the majori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88f14ccf178759e5603699a2fd07f66
https://doi.org/10.1097/pai.0b013e3181f09311
https://doi.org/10.1097/pai.0b013e3181f09311
Autor:
Sumana Choudhury, Timothy A. Bertram, Andrew T Bruce, Thomas Spencer, Joydeep Basu, Elias Rivera, Deepak Jain, Russell W. Kelley, Namrata Sangha, Roger M. Ilagan, Kelly I. Guthrie
Publikováno v:
Regenerative medicine. 10(7)
Aim: Identification of mechanistic pathways for selected renal cell (SRC) therapeutic bioactivity in rodent models of chronic kidney disease. Materials & methods: In vivo and in vitro functional bioassays applied to investigate regenerative outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d10d2a31512bb3bbc5ad2fe9a44ea2
https://pubmed.ncbi.nlm.nih.gov/26568079
https://pubmed.ncbi.nlm.nih.gov/26568079
Autor:
Eric S. Werdin, Anjali N. Rao, Thomas Spencer, Benjamin D. Humphreys, Sumana Choudhury, Rusty Kelley, Fengfeng Xu, Manuel J. Jayo, Sharon C. Presnell, Tim Bertram, Kelly I. Guthrie, Shay M. Wallace, Andrew T. Bruce, Elias A. Rivera, Roger M. Ilagan
Publikováno v:
Cell Transplantation, Vol 22 (2013)
New treatment paradigms that slow or reverse progression of chronic kidney disease (CKD) are needed to relieve significant patient and healthcare burdens. We have shown that a population of selected renal cells (SRCs) stabilized disease progression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a617da70362e513fe6dc0de3f70464
https://doaj.org/article/7ca09f8c5c4946ad93f5e619fe9d10b5
https://doaj.org/article/7ca09f8c5c4946ad93f5e619fe9d10b5
Publikováno v:
Trends in biotechnology. 31(9)
Methodologies for the rigorous and quantitative evaluation of biological activity or potency are an essential aspect of the developmental pathway for all biologic product candidates. Such assays typically leverage key mechanistic pathways demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031c86ef99d1afcd68e0421303f95c77
https://pubmed.ncbi.nlm.nih.gov/23932143
https://pubmed.ncbi.nlm.nih.gov/23932143
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1001
Regenerative medicine and tissue engineering approaches for solving current medical dilemmas such as organ failure, congenital defect, or reconstruction following disease or trauma typically require specific considerations regarding biomaterial selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50bad6e74e89e0623fda71999d876b16
https://pubmed.ncbi.nlm.nih.gov/23494430
https://pubmed.ncbi.nlm.nih.gov/23494430