Cross-reactive immunity against SARS-CoV-2 N protein in Central and West Africa precedes the COVID-19 pandemic

Autor: Jannie Pedersen, Ismaël Hervé Koumakpayi, Giorgi Babuadze, Mariana Baz, Oumar Ndiaye, Oumar Faye, Cheikh Tidiane Diagne, Ndongo Dia, Maedeh Naghibosadat, Allison McGeer, Samira Muberaka, Irène P. Moukandja, Stella Ndidi, Carlos B. Tauil, Jean-Bernard Lekana-Douki, Cheikh Loucoubar, Ousmane Faye, Amadou Sall, Kelly G. Magalhães, Nina Weis, Robert Kozak, Gary P. Kobinger, Hugues Fausther-Bovendo

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)

Abstract Early predictions forecasted large numbers of severe acute respiratory syndrome coronavirus (SARS-CoV-2) cases and associated deaths in Africa. To date, Africa has been relatively spared. Various hypotheses were postulated to explain the low

Externí odkaz: https://doaj.org/article/65359801153e4dbb96829253ba439e41

Granzyme A in Chikungunya and Other Arboviral Infections

Autor: Alessandra S. Schanoski, Thuy T. Le, Dion Kaiserman, Caitlin Rowe, Natalie A. Prow, Diego D. Barboza, Cliomar A. Santos, Paolo M. A. Zanotto, Kelly G. Magalhães, Luigi Aurelio, David Muller, Paul Young, Peishen Zhao, Phillip I. Bird, Andreas Suhrbier

Publikováno v: Frontiers in Immunology, Vol 10 (2020)

Granzyme A (GzmA) is secreted by cytotoxic lymphocytes and has traditionally been viewed as a mediator of cell death. However, a growing body of data suggests the physiological role of GzmA is promotion of inflammation. Here, we show that GzmA is sig

Externí odkaz: https://doaj.org/article/8880a150ba424bb2bd4a4fe6b50c7fd9

Schistosomal Lipids Activate Human Eosinophils via Toll-Like Receptor 2 and PGD2 Receptors: 15-LO Role in Cytokine Secretion

Autor: Kelly G. Magalhães, Tatiana Luna-Gomes, Fabio Mesquita-Santos, Rafael Corrêa, Leonardo Santos Assunção, Georgia Correa Atella, Peter F. Weller, Christianne Bandeira-Melo, Patricia T. Bozza

Publikováno v: Frontiers in Immunology, Vol 9 (2019)

Parasite-derived lipids may play important roles in host-pathogen interactions and immune evasion mechanisms. Remarkable accumulation of eosinophils is a characteristic feature of inflammation associated with parasitic disease, especially caused by h

Externí odkaz: https://doaj.org/article/560cf469967942eab486adab29e5bbfa

Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms

Autor: Thiago Viana de Freitas, Utsa Karmakar, Andreanne G. Vasconcelos, Michele A. Santos, Bianca Oliveira do Vale Lira, Samuel Ribeiro Costa, Eder Alves Barbosa, José Cardozo-Fh, Rafael Correa, Dalila J.S. Ribeiro, Maura Vianna Prates, Kelly G. Magalhães, Marcelo Henrique Soller Ramada, José Roberto de Souza Almeida Leite, Carlos Bloch, Aline Lima de Oliveira, Marc Vendrell, Guilherme Dotto Brand

Publikováno v: Viana de freitas, T, Karmakar, U, Vasconcelos, A, Santos, M, Oliveira do vale lira, B, Costa, S, Barbosa, E, Cardozo-Fh, J, Correa, R, Ribeiro, D S, Prates, M, Magalhães, K, Soller ramada, M, Roberto de souza almeida leite, J, Bloch, C, Lima de oliveira, A, Vendrell, M & Brand, G 2023, ' Release of immunomodulatory peptides at bacterial membrane interfaces as a novel strategy to fight microorganisms ', Journal of Biological Chemistry, vol. 299, no. 4, 103056, pp. 103056 . https://doi.org/10.1016/j.jbc.2023.103056
J Biol Chem

Cationic and amphiphilic peptides can be used as homing devices to accumulate conjugated antibiotics to bacteria-enriched sites and promote efficient microbial killing. However, just as important as tackling bacterial infections, is the modulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7735476505ebb74413df457e6398e567
https://www.pure.ed.ac.uk/ws/files/332308457/PIIS0021925823001886_3_.pdf

Dietary inflammatory index and its relationship with gut microbiota in individuals with intestinal constipation: a cross-sectional study

Autor: Lorena M, Costa, Marcela M, Mendes, Amanda C, Oliveira, Kelly G, Magalhães, Nitin, Shivappa, James R, Hebert, Teresa H M, da Costa, Patrícia B, Botelho

Publikováno v: European journal of nutrition. 61(1)

To determine whether there is an association between the inflammatory potential of the diet, measured by the dietary inflammatory index (DII®), and the composition of intestinal microbiota in adults with functional constipation (FC).A cross-sectiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1db695c6fc4c4af18179eb8c0908e6e6
https://pubmed.ncbi.nlm.nih.gov/34351455