Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelly E. Theisen"'
Autor:
Ileini N. Espino, Julia Drolet, Ty-niquia Jones, Antonette Uwechue, Brittany Koehler, Raquel Beaird, Sanni Maione, Christine Darrah, Rana Hijazi, Christopher James, Annabelle Dupre, Ewa Koscinski, Leilani Creft, Michael Giampaolo, Alexandre Bernier, Kelly E. Theisen
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101796- (2024)
The bacterial cell-division protein FtsZ has been a promising antibiotic target for over a decade now, but there is still a need for more work in this area. So far there are no FtsZ targeting drugs commercially available. We have analyzed a wide vari
Externí odkaz:
https://doaj.org/article/1e3fe63c37db4f3092eb3c88fe340217
Autor:
Richele J. Thompson, Daina Zeng, David K. Jung, John Cavanagh, Kelly E. Theisen, C. Leigh Allen, Christian Melander, Roberta J. Melander, Erik A. Feldmann, Matthew D. Stephens, Morgan E. Milton, Benjamin G. Bobay
Publikováno v:
Molecular Microbiology. 106:223-235
With antibiotic resistance increasing at alarming rates, targets for new antimicrobial therapies must be identified. A particularly promising target is the bacterial two-component system. Two-component systems allow bacteria to detect, evaluate and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52b9eb78320323ad709a23687c2355c9
https://doi.org/10.1111/mmi.13759
https://doi.org/10.1111/mmi.13759
Autor:
Kelly E. Theisen
Publikováno v:
Biophysical Journal. 120:90a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa1cde719f2924310a78e896385ee19
https://doi.org/10.1016/j.bpj.2020.11.750
https://doi.org/10.1016/j.bpj.2020.11.750
Autor:
Morgan E, Milton, C Leigh, Allen, Erik A, Feldmann, Benjamin G, Bobay, David K, Jung, Matthew D, Stephens, Roberta J, Melander, Kelly E, Theisen, Daina, Zeng, Richele J, Thompson, Christian, Melander, John, Cavanagh
Publikováno v:
Molecular microbiology. 106(2)
With antibiotic resistance increasing at alarming rates, targets for new antimicrobial therapies must be identified. A particularly promising target is the bacterial two-component system. Two-component systems allow bacteria to detect, evaluate and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fadef20ef5005c66840a96803a0f922
https://pubmed.ncbi.nlm.nih.gov/28755524
https://pubmed.ncbi.nlm.nih.gov/28755524
Publikováno v:
The Journal of Physical Chemistry B. 116:8545-8555
Large-size biomolecular systems that spontaneously assemble, disassemble, and self-repair by controlled inputs play fundamental roles in biology. Microtubules (MTs), which play important roles in cell adhesion and cell division, are a prime example.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7095aa22e5d86955263e137c74e9b1fd
https://doi.org/10.1021/jp212608f
https://doi.org/10.1021/jp212608f
Autor:
Dale R. Merz, Gail Yacyshyn, Ruxandra I. Dima, Kelly E. Theisen, Dejana Mokranjac, Daniela Bauer, Gabriel Žoldák, Matthias Rief, Benjamin Pelz
The regulation of protein function through ligand-induced conformational changes is crucial for many signal transduction processes. The binding of a ligand alters the delicate energy balance within the protein structure, eventually leading to such co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad3baa3b5293c204edad7a4644485b0
https://europepmc.org/articles/PMC4547238/
https://europepmc.org/articles/PMC4547238/
Autor:
Kelly E. Theisen, Yaroslav Kholodov, Valeri Barsegov, Ruxandra I. Dima, Olga Kononova, Ekaterina L. Grishchuk, Fazly I. Ataullakhanov, Kenneth A. Marx
Publikováno v:
Journal of the American Chemical Society
Microtubules, the primary components of the chromosome segregation machinery, are stabilized by longitudinal and lateral non-covalent bonds between the tubulin subunits. However, the thermodynamics of these bonds and the microtubule physico-chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ae11f73650b5fab9ab84029c0174b0
Autor:
Kelly E. Theisen, Yaroslav Kholodov, Ruxandra I. Dima, Valeri Barsegov, Kenneth A. Marx, Fazly I. Ataullakhanov, Ekaterina L. Grishchuk, Olga Kononova
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 33:35-36
Microtubules, the primary components of the chromosome segregation machinery, are stabilized by longitudinal and lateral noncovalent bonds between the tubulin subunits. However, the thermodynamics of these bonds and the microtubule physicochemical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ba2b9cb6bbbbf0fb3b25d60d86ca46
https://doi.org/10.1080/07391102.2015.1032601
https://doi.org/10.1080/07391102.2015.1032601
Publikováno v:
The Journal of Chemical Physics. 139:121926
We investigate the mechanical behavior of microtubule (MT) protofilaments under the action of bending forces, ramped up linearly in time, to provide insight into the severing of MTs by microtubule associated proteins (MAPs). We used the self-organize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7581bc936574ac03ac8c95ceb61d217
https://doi.org/10.1063/1.4819817
https://doi.org/10.1063/1.4819817
Publikováno v:
Biophysical Journal. (9):2322-2332
The titin-telethonin complex, essential for anchoring filaments in the Z-disk of the sarcomere, is composed of immunoglobulin domains. Surprisingly, atomic force microscopy experiments showed that it resists forces much higher than the typical immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4e26edaac247fcc17e796dc0ce2de9