Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kelly E. McKinnon"'
Autor:
Justin D. Finkle, Hala Boulos, Terri M. Driessen, Christine Lo, Richard A. Blidner, Ashraf Hafez, Aly A. Khan, Ariane Lozac’hmeur, Kelly E. McKinnon, Jason Perera, Wei Zhu, Afshin Dowlati, Kevin P. White, Robert Tell, Nike Beaubier
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-invasive approach to identify biomarkers, detect resistance mutations, monitor disease burden, and identify early recurrence. The Tempus xF liquid biopsy
Externí odkaz:
https://doaj.org/article/439e514d758c4462a85579f192a11c43
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract BRCA-mutant cancers often develop therapeutic resistance through several mechanisms. Here, we report a case of pathogenic germline BRCA2-driven breast cancer monitored for disease progression and acquired resistance using longitudinal multi-
Externí odkaz:
https://doaj.org/article/36355c8205f84120b0841747327b4cc3
Autor:
Brian M. Larsen, Madhavi Kannan, Lee F. Langer, Benjamin D. Leibowitz, Aicha Bentaieb, Andrea Cancino, Igor Dolgalev, Bridgette E. Drummond, Jonathan R. Dry, Chi-Sing Ho, Gaurav Khullar, Benjamin A. Krantz, Brandon Mapes, Kelly E. McKinnon, Jessica Metti, Jason F. Perera, Tim A. Rand, Veronica Sanchez-Freire, Jenna M. Shaxted, Michelle M. Stein, Michael A. Streit, Yi-Hung Carol Tan, Yilin Zhang, Ende Zhao, Jagadish Venkataraman, Martin C. Stumpe, Jeffrey A. Borgia, Ashiq Masood, Daniel V.T. Catenacci, Jeremy V. Mathews, Demirkan B. Gursel, Jian-Jun Wei, Theodore H. Welling, Diane M. Simeone, Kevin P. White, Aly A. Khan, Catherine Igartua, Ameen A. Salahudeen
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109429- (2021)
Summary: Patient-derived tumor organoids (TOs) are emerging as high-fidelity models to study cancer biology and develop novel precision medicine therapeutics. However, utilizing TOs for systems-biology-based approaches has been limited by a lack of s
Externí odkaz:
https://doaj.org/article/9e05120e2cf8481abf4978520140395c
Autor:
Shuo Xiao, Jonathan R. Coppeta, Hunter B. Rogers, Brett C. Isenberg, Jie Zhu, Susan A. Olalekan, Kelly E. McKinnon, Danijela Dokic, Alexandra S. Rashedi, Daniel J. Haisenleder, Saurabh S. Malpani, Chanel A. Arnold-Murray, Kuanwei Chen, Mingyang Jiang, Lu Bai, Catherine T. Nguyen, Jiyang Zhang, Monica M. Laronda, Thomas J. Hope, Kruti P. Maniar, Mary Ellen Pavone, Michael J. Avram, Elizabeth C. Sefton, Spiro Getsios, Joanna E. Burdette, J. Julie Kim, Jeffrey T. Borenstein, Teresa K. Woodruff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The female reproductive tract constitutes the ovary, fallopian tubes, uterus, and cervix, but it is challenging to engineer this systemin vitro. Here, the authors develop a microfluidic device (EVATAR) with reproductive tract and peripheral tissues t
Externí odkaz:
https://doaj.org/article/502594c466a14109b2eb6d7e22593a42
Publikováno v:
Biol Reprod
To investigate genomic pathways that may influence physiology and infectivity during the menstrual cycle, RNA sequence analysis was performed on patient-matched engineered ectocervical tissue after follicular and luteal phase (LP) hormone treatments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0249ca70775b19f714c928c53c677f06
https://doi.org/10.1093/biolre/ioaa056
https://doi.org/10.1093/biolre/ioaa056
Publikováno v:
Journal of Clinical Oncology. 40:261-261
261 Background: As the incidence of cutaneous squamous cell carcinoma (cSCC) continues to rise and newer systemic therapies become available, coordination of care between dermatologists and oncologists will be vital to provide quality, patient-center
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c4dab67da013ad2787a1cb744ec8e5
https://doi.org/10.1200/jco.2022.40.28_suppl.261
https://doi.org/10.1200/jco.2022.40.28_suppl.261
Publikováno v:
Journal of Clinical Oncology. 40:56-56
56 Background: Tenosynovial giant cell tumor (TGCT) is a rare soft tissue sarcoma that is difficult to treat due to location, high risk of recurrence, and potential for significant morbidity. Recent approvals of novel systemic therapies provide new o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299f334cbdb5aef5e918e7e436d4600d
https://doi.org/10.1200/jco.2022.40.28_suppl.056
https://doi.org/10.1200/jco.2022.40.28_suppl.056
Autor:
Ashraf T. Hafez, Christine Lo, Justin D. Finkle, Hala Boulos, Wei Zhu, Robert Tell, Richard A. Blidner, Kevin P. White, Terri M. Driessen, Nike Beaubier, Ariane Lozac’hmeur, Kelly E. McKinnon, Aly A. Khan, Jason Perera, Afshin Dowlati
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
NPJ Precision Oncology
NPJ Precision Oncology
Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-invasive approach to identify biomarkers, detect resistance mutations, monitor disease burden, and identify early recurrence. The Tempus xF liquid biopsy assay is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd397bcba9f12f4a2de99afe4a8e0aa0
https://doi.org/10.1038/s41698-021-00202-2
https://doi.org/10.1038/s41698-021-00202-2
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-6 (2021)
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-6 (2021)
BRCA-mutant cancers often develop therapeutic resistance through several mechanisms. Here, we report a case of pathogenic germline BRCA2-driven breast cancer monitored for disease progression and acquired resistance using longitudinal multi-tissue ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c881760bbb2e0088e407d0a1a8eeef9b
http://europepmc.org/articles/PMC7900170
http://europepmc.org/articles/PMC7900170
Autor:
Theodore H. Welling, Diane M. Simeone, Benjamin A. Krantz, Aïcha BenTaieb, Andrea Cancino, Chi Sing Ho, Jeffrey A. Borgia, Jeremy V. Mathews, Brandon Mapes, Michael A. Streit, Jian Jun Wei, Ameen A. Salahudeen, Bridgette E. Drummond, Veronica Sanchez-Freire, Martin C. Stumpe, Aly A. Khan, Tim A. Rand, Ende Zhao, Kelly E. McKinnon, Benjamin D. Leibowitz, Demirkan B. Gursel, Madhavi Kannan, Jagadish Venkataraman, Yi-Hung Carol Tan, Brian M. Larsen, Jonathan R. Dry, Gaurav Khullar, Jenna M. Shaxted, Catherine Igartua, Kevin P. White, Daniel V.T. Catenacci, Ashiq Masood, Jason Perera, Jessica Metti, Michelle M. Stein, Igor Dolgalev, Lee F. Langer, Yilin Zhang
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109429-(2021)
Summary: Patient-derived tumor organoids (TOs) are emerging as high-fidelity models to study cancer biology and develop novel precision medicine therapeutics. However, utilizing TOs for systems-biology-based approaches has been limited by a lack of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ee6070df11c2b91a956a81ab264980
https://pubmed.ncbi.nlm.nih.gov/34320344
https://pubmed.ncbi.nlm.nih.gov/34320344