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Autor:
Nathalie Jolly, Marie-Lise Gougeon, Béatrice Poirier, Stéphane Béchet, Philippe Morand, Odile Launay, Raphaela Giemza, Anna Ndiaye, Muriel Vray, Julie Johnson, Claire Poyart, Nicola Fenner, Philippe J. Sansonetti, Valérie Seffer, Kelly Dowling, David J. M. Lewis, Diane van der Vliet, Christine Sadorge
Publikováno v:
Vaccine. 27:1184-1191
SC599 vaccine is a live Shigella dysenteriae 1 strain attenuated by deletion of invasion [icsA], iron chelation [ent, fep] and shiga toxin A subunit [stxA] genes. In a preliminary Phase 1 single dose prospective study, we showed that SC599 vaccine wa