Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kelly D. Stone"'
Publikováno v:
The journal of allergy and clinical immunology. In practice. 10(12)
The U.S. Food and Drug Administration (FDA) regulates a variety of products, including medical, food, and tobacco products. Prior to the creation of the FDA, there were few protections to the public around the contents and sale of food and pharmaceut
Autor:
Hana Alachkar, Kathleen E. Sullivan, Claire Bethune, Erica Brittain, Niall Conlon, Neil Romberg, Claire Langley, Shanmuganathan Chandrakasan, Daniel Veltri, Matthew C. Cook, Bahar Miraghazadeh, Kelly D. Stone, Stefanie Frey-Jakobs, Jeffrey I. Cohen, Andrew L. Snow, Sinisa Savic, Sophie Hambleton, Maria Cecilia Poli, Arturo Borzutzky, Alexandra F. Freeman, Jeffrey R. Stinson, Michael B. Jordan, Michael A. Weinreich, T. Prescott Atkinson, Troy R. Torgerson, Michele P. Lambert, Alejandro A. Schäffer, T. Ronan Leahy, Celeste G Nelson, Peter D. Arkwright, Ivan K. Chinn, Stephan Weidinger, Laura Lucas, Tracy A Briggs, Martha Nason, Kenneth Paris, Smita Y. Patel, Sandhya Limaye, Sebastian Fuchs, Julia M. Hartberger, Bodo Grimbacher, Batsukh Dorjbal, Stephan Ehl, Amy Theos, Sergey Nejentsev, Andrew F. Whyte, Lena Moebus, Andrew J. Oler, Thomas DiMaggio, Joie Davis, Andre Franke, Chi Ma, Joshua D. Milner, Alla Bulashevska, Jeffrey D. Lebensburger
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:1482-1495
Background Caspase activation and recruitment domain 11 (CARD11) encodes a scaffold protein in lymphocytes that links antigen receptor engagement with downstream signaling to nuclear factor κB, c-Jun N-terminal kinase, and mechanistic target of rapa
Autor:
Michael A. Weinreich, Megan A. Cooper, Pia J. Hauk, Thomas DiMaggio, Batsukh Dorjbal, Geronimo Dubra, Eric Meffre, Brian S. Kim, Jonathan J. Lyons, Jordan K. Abbott, Erwin W. Gelfand, Chi Ma, Emma Prieto, Kelly D. Stone, Joshua D. Milner, Natsuko Yamakawa, Jeffrey R. Stinson, Silvia Danielian, Jonathan Zaiat, Paul R. Reynolds, Andrew L. Snow, Swadhinya Arjunaraja, Yu Zhang, Elisa Ruffo, Salomé Glauzy, Sergio D. Rosenzweig, Jennifer Stoddard, Marcelo A. Martí, Matías Oleastro, Nina Jones, Neil Romberg, Alejandro Palma, Kelsey Voss, Celeste G Nelson, Joshua J McElwee, Julie E. Niemela, Helen F. Matthews, Yuan Zhang, Andrea Bernasconi
Publikováno v:
Nature Genetics. 49:1192-1201
Few monogenic causes for severe manifestations of common allergic diseases have been identified. Through next-generation sequencing on a cohort of patients with severe atopic dermatitis with and without comorbid infections, we found eight individuals
Autor:
Alexandra F. Freeman, E. Mendoza-Caamal, Robert J. Hohman, Monica G. Lawrence, Kendal A. Karpe, Kelly D. Stone, Celeste G Nelson, Jason D. Hughes, Jonathan J. Lyons, Xiaomin Yu, Nina Jones, Tom DiMaggio, Steve M. Holland, Michael P. O'Connell, Chi Ma, Joshua McElwee, Joshua D. Milner, Dirk Darnell, L. Orozco, Andrea M. Siegel, Ming Zhao, Yuan Zhang, Pamela A. Frischmeyer-Guerrerio, Marc E. Rothenberg, Yihui Liu
Publikováno v:
The Journal of Experimental Medicine
Lyons et al. show that STAT3 negatively regulates TGF-β signaling via ERBIN and that cell-intrinsic deregulation of TGF-β pathway activation promotes the IL-4/IL-4Rα/GATA3 axis to support atopic phenotypes in humans.
Nonimmunological connecti
Nonimmunological connecti
Autor:
Daniel Petroni, Russell Barker, Tom DiMaggio, Joshua D. Milner, Kelly D. Stone, Lybil B. Mendoza Alvarez, Jamie A. Rosenthal, Jonathan J. Lyons, Celeste Nelson, Sara C. Glover
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 124(1)
Autor:
Dean D. Metcalfe, Hirsh D. Komarow, Joshua D. Milner, Melody C. Carter, Robin Eisch, Kathryn J. Sowerwine, Michael P. O'Connell, Nina Jones, Steven M. Holland, Kelly D. Stone, Jack Chovanec, Yihui Liu, Mehdi Pirooznia, Laura Wisch, Irina Maric, Christa S. Zerbe, Jonathan J. Lyons, Avanti Desai, Amy P. Hsu, Monica G. Lawrence, Ilker Tunc, Chyi-Chia Richard Lee, Xiaoping Sun, Jiwon Kim, Lisa Boris
Publikováno v:
The Journal of allergy and clinical immunology. 144(2)
Autor:
Jeffrey G. Demain, David M. Lang, Kelly D. Stone, David B. Peden, Sharon Markovics, Mary Beth Fasano, Paul V. Williams, Melody C. Carter, Robert A. Wood, Thomas B. Casale, Mitchell H. Grayson, Kathleen E. Sullivan, Chitra Dinakar, Scott H. Sicherer, Thomas A. Fleisher, David A. Khan, Paula J. Busse
Publikováno v:
Allergy.
Autor:
Rekha D. Jhamnani, Erica Brittain, Pamela A. Frischmeyer-Guerrerio, Magnus P. Borres, Kelly D. Stone, Samara Levin, Anthony L. Guerrerio, Marjohn Rasooly, Wenjuan Gu, Joshua D. Milner, Joseph E. Jones
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 122(4)
Background Diagnosing food allergy in patients with atopic dermatitis (AD) is complicated by their high rate of asymptomatic sensitization to foods, which can lead to misdiagnosis and unnecessary food avoidance. Objective We sought to determine wheth
Autor:
Fabio Candotti, Jonathan J. Lyons, Elizabeth Garabedian, Paul Sackstein, Willem S. Lexmond, Nina Jones, Jeremy A. Goettel, Daniel Kotlarz, Adrian J. Thrasher, Edda Fiebiger, Scott B. Snapper, Thomas DiMaggio, Kelly D. Stone, Celeste Nelson, Justin Jacobse, Marion M. Deken, Joshua D. Milner, Monica G. Lawrence, Edmond H. H. M. Rings
Publikováno v:
Journal of Clinical Investigation, 126(10), 4030-4044. The American Society for Clinical Investigation
Journal of Clinical Investigation, 126(10), 4030-4044
Journal of Clinical Investigation, 126(10), 4030-4044
In addition to the infectious consequences of immunodeficiency, patients with Wiskott-Aldrich syndrome (WAS) often suffer from poorly understood exaggerated immune responses that result in autoimmunity and elevated levels of serum IgE. Here, we have
Autor:
Steven M. Holland, Kelly D. Stone, Jennifer Grossman, Heardley M. Murdock, Alexandra F. Freeman, Mark Parta, Dennis D. Hickstein, Catherine M. Bollard, Helen C. Su, Jennifer Cuellar-Rodriguez, Juan Gea-Banacloche, Niki M. Moutsopoulos, Heidi H. Kong, Nirali N. Shah
Publikováno v:
Biology of Blood and Marrow Transplantation. 21:1037-1045
We performed allogeneic hematopoietic stem cell transplantation in six patients with mutations in the dedicator-of-cytokinesis 8 (DOCK8) gene using a myeloablative conditioning regimen consisting of busulfan 3.2 mg/kg/day IV for 4 days and fludarabin