Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Kelly D McCall"'
Autor:
Davoud Ghazanfari, Maria Cecilia Courreges, Lydia E. Belinski, Michael J. Hogrell, Jacob Lloyd, Stephen C. Bergmeier, Kelly D. McCall, Douglas J. Goetz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract During a SARS-CoV-2 infection, macrophages recognize viral components resulting in cytokine production. While this response fuels virus elimination, overexpression of cytokines can lead to severe COVID-19. Previous studies suggest that the s
Externí odkaz:
https://doaj.org/article/56233cae8bb2417da30fac712d7f764f
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117556 (2015)
BACKGROUND:Clinical studies suggest that short-term insulin treatment in new-onset type 2 diabetes (T2DM) can promote prolonged glycemic control. The purpose of this study was to establish an animal model to examine such a "legacy" effect of early in
Externí odkaz:
https://doaj.org/article/bc4e0896573f411b8502e2501bd3b74c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/cbf3bc2405d848018dc690418a7bbdb4
Autor:
Debra L. Walter, Jean R. Thuma, Ramiro Malgor, Frank L. Schwartz, Kelly D. McCall, Karen T. Coschigano
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2357 (2021)
Despite the 2019 Executive Order on Advancing American Kidney Health Initiative, kidney disease has moved up in rank from the 9th to the 8th leading cause of death in the United States. A recent push in the field of nephrology has been to identify mo
Externí odkaz:
https://doaj.org/article/6e94f8d413a848c5830c3782b370c140
Autor:
Davoud Ghazanfari, Maria Cecilia Courreges, Lydia Belinski, Stephen C. Bergmeier, Kelly D. McCall, Douglas J. Goetz
Publikováno v:
Biochemical and Biophysical Research Communications. 605:171-176
A key component of severe COVID-19 is a "cytokine storm" i.e., the excessive expression of unneeded cytokines. Previous studies suggest that SARS-CoV-2 proteins can induce macrophages to secrete pro-inflammatory cytokines; a process that may involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b179c5e64dfc71c32e66a445c274d71e
https://doi.org/10.1016/j.bbrc.2022.03.035
https://doi.org/10.1016/j.bbrc.2022.03.035
Publikováno v:
BioTechniques, Vol 60, Iss 6, Pp 293-298 (2016)
RNA isolation from pancreatic islets poses unique challenges. Here, we present a reproducible means of obtaining high-quality RNA from juvenile rodent islets in sufficient quantities for use in ex vivo expression studies. Tissue was extracted from fe
Externí odkaz:
https://doaj.org/article/f3afcc2d365d4a7d8d1fae7ba71971b1
Autor:
Sarah E, Benner, Debra L, Walter, Jean R, Thuma, Maria, Courreges, Calvin B L, James, Frank L, Schwartz, Kelly D, McCall
Publikováno v:
Pancreas. 51:48-55
Genetic and environmental influences play a role as triggers of type 1 diabetes mellitus (T1DM). Female nonobese diabetic (NOD) mice are useful for studying T1DM as they spontaneously develop T1DM, which can be accelerated by some viruses. Toll-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa05aea1668dcd2ad5101402ff2dcb76
https://doi.org/10.1097/mpa.0000000000001960
https://doi.org/10.1097/mpa.0000000000001960
Autor:
Karen T. Coschigano, Sarah E Benner, Ramiro Malgor, Kelly D. McCall, Debra L. Walter, Rosemary Jane Oaks, Frank L. Schwartz, Jean R. Thuma
Publikováno v:
Viral Immunol
End-stage renal disease (ESRD) is described by four primary diagnoses, diabetes, hypertension, glomerulonephritis, and cystic kidney disease, all of which have viruses implicated as causative agents. Enteroviruses, such as coxsackievirus (CV), are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1330f2cbfdd4ace9f510ec520cd7ed1
https://doi.org/10.1089/vim.2019.0188
https://doi.org/10.1089/vim.2019.0188
Autor:
Melissa R. Kauffman, Kelly D. McCall, Nathan M. Reynolds, Ahmed Faik, Monica M. Burdick, Saeed Nazemidashtarjandi, Abigail E. Allen, Davoud Ghazanfari, Douglas J. Goetz
Publikováno v:
Leuk Res
The role of interferon-gamma (IFN-γ) in Chronic Myelogenous/Myeloid Leukemia (CML) and in the treatment of CML remains unclear; specifically, the effect of IFN-γ on apoptosis. There is reported interplay between IFN-γ and glycogen synthase kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193520c2784fae23951c6bdc64e50a89
https://europepmc.org/articles/PMC7740760/
https://europepmc.org/articles/PMC7740760/
Autor:
Maria C. Courreges, Stephen C. Bergmeier, Douglas J. Goetz, Mahboubeh S. Noori, Kelly D. McCall
Publikováno v:
European Journal of Pharmacology
Sepsis is a serious condition that can lead to long-term organ damage and death. At the molecular level, the hallmark of sepsis is the elevated expression of a multitude of potent cytokines, i.e. a cytokine storm. For sepsis involving gram-negative b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7067b2d85f1727a504b39a152e9129
https://pubmed.ncbi.nlm.nih.gov/32634441
https://pubmed.ncbi.nlm.nih.gov/32634441