Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kelly D Garcia"'
Autor:
Kyle M. Schachtschneider, Regina M. Schwind, Jordan Newson, Nickolas Kinachtchouk, Mark Rizko, Nasya Mendoza-Elias, Paul Grippo, Daniel R. Principe, Alex Park, Nana H. Overgaard, Gregers Jungersen, Kelly D. Garcia, Ajay V. Maker, Laurie A. Rund, Howard Ozer, Ron C. Gaba, Lawrence B. Schook
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Despite an improved understanding of cancer molecular biology, immune landscapes, and advancements in cytotoxic, biologic, and immunologic anti-cancer therapeutics, cancer remains a leading cause of death worldwide. More than 8.2 million deaths were
Externí odkaz:
https://doaj.org/article/8dff86425b604f0c97e8dd912caef9eb
Autor:
Jiaqi Wu, Francesca V. LoBianco, Lawrence B. Schook, Maureen Regan, Kelly D. Garcia, Lobna Elkhadragy, Aisha Qazi, Herbert E. Whiteley, Matthew C. Stewart, Faith M. Thomas, Grace Guzman, Lauretta A. Rund, Regina M. Schwind, F. Edward Boas, Ron C. Gaba, Hanna H. Chen, Eileena F. Giurini, Kyle M. Schachtschneider, Mohammed El-Kebir, Sulalita Chaki, Mario F. Neto, Jordan L. Newson
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. New animal models that faithfully recapitulate human HCC phenotypes are required to address unmet clinical needs and advance standard-of-care therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a95655aec3b4a8f4b2e1c658316c8ec
https://doi.org/10.18632/oncotarget.27647
https://doi.org/10.18632/oncotarget.27647
Autor:
Laura M. Sanchez, Cheryl Perkins, Alanna R. Condren, Kathleen A Coda, Alexandra A Smith, Yujia Deng, Jeffrey D Fortman, Kelly D Garcia
Publikováno v:
J Am Assoc Lab Anim Sci
The number of zebrafish in biomedical research has increased exponentially over the past decades, leading to pressure on the laboratory animal community to develop and refine techniques to monitor zebrafish health so that suitable stocks can be maint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54f45bfdff7cdedff06912f989c0765
https://pubmed.ncbi.nlm.nih.gov/34470695
https://pubmed.ncbi.nlm.nih.gov/34470695
Autor:
Kelly D. Garcia, Michael Eichner
Publikováno v:
Laboratory Animals. 53:634-640
A cohort of captive-bred red-eared slider turtles, Trachemys scripta, was received from a commercial vendor. Shortly after arrival, several turtles presented as lethargic with subjectively pale skin and multifocal areas of cotton-like tufts in the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1f79bc13fe7860404f44fd340d6196
https://doi.org/10.1177/0023677219858166
https://doi.org/10.1177/0023677219858166
Autor:
Maureen Regan, Lawrence B. Schook, Ron C. Gaba, Matthew C. Stewart, Kimia Dasteh Goli, Shovik Patel, Lobna Elkhadragy, William M. Totura, Kelly D. Garcia, Kyle M. Schachtschneider
Publikováno v:
Biotechniques
Pigs provide a valuable large animal model for several diseases due to their similarity with humans in anatomy, physiology, genetics and drug metabolism. We recently generated a porcine model for TP53R167H and KRASG12D driven hepatocellular carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be377d4c2641ee555240c21151a1627
https://pubmed.ncbi.nlm.nih.gov/33222517
https://pubmed.ncbi.nlm.nih.gov/33222517
Publikováno v:
J Am Assoc Lab Anim Sci
One of the goals of environmental enrichment is to encourage species-typical behaviors, while discouraging abnormal behaviors or stereotypies. Assessing the effectiveness of various enrichment modalities can be challenging, particularly for prey spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d29ff4c15519b51d32aa7485a101d42
https://doi.org/10.30802/aalas-jaalas-19-000136
https://doi.org/10.30802/aalas-jaalas-19-000136
Publikováno v:
ILAR Journal. 59:99-110
The role of comparative oncology in translational research is receiving increasing attention from drug developers and the greater biomedical research community. Pet dogs with spontaneous cancer are important and underutilized translational models, ow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a592d0090ecef1d0baaabb114624d35d
https://doi.org/10.1093/ilar/ily019
https://doi.org/10.1093/ilar/ily019
Autor:
Alexandra A Smith, Yu-Hui Huang, Kelly D. Garcia, R. Peter Lokken, Ramzy C. Khabbaz, Ron C. Gaba
Publikováno v:
Journal of Visualized Experiments.
The rabbit VX2 tumor is an animal model commonly utilized for translational research regarding hepatocellular carcinoma (HCC) in the field of Interventional Radiology. This model employs an anaplastic squamous cell carcinoma that is easily and reliab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3421541f38945b30513c0b451a47b70b
https://doi.org/10.3791/58600
https://doi.org/10.3791/58600
Autor:
Lawrence B. Schook, Lauretta A. Rund, R. Peter Lokken, Nasya Mendoza-Elias, Kelly D. Garcia, Daniel P. Regan, Michael Eichner, Faith M. Thomas, Regina M. Schwind, Kyle M. Schachtschneider, Ron C. Gaba
Publikováno v:
Journal of vascular and interventional radiology : JVIR, vol 29, iss 8
PurposeThis study used the Oncopig Cancer Model (OCM) to develop alcohol-induced fibrosis in a porcine model capable of developing hepatocellular carcinoma.Materials and methodsLiver injury was induced in 8-week-old Oncopigs (n= 10) via hepatic trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb0265af9385a9c81f31270ec3b0a2a
https://europepmc.org/articles/PMC6388685/
https://europepmc.org/articles/PMC6388685/
Publikováno v:
Muscle & Nerve. 53:260-268
Introduction: Reports of muscle testing are frequently limited to maximal force alone. The experiments reported here show that force generation and relaxation rates can be obtained from the same experiments and provide a more complete functional char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c70d3e5fc0112890bf655d7704b7541
https://doi.org/10.1002/mus.24714
https://doi.org/10.1002/mus.24714