Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kelly Colombo"'
Autor:
Randall J. Kimple, Francis S. Willard, Stephan W. Grill, Kelly Colombo, Pierre Gönczy, David P. Siderovski
Publikováno v:
Science. 300:1957-1961
Asymmetric divisions are crucial for generating cell diversity; they rely on coupling between polarity cues and spindle positioning, but how this coupling is achieved is poorly understood. In one-cell stage Caenorhabditis elegans embryos, polarity cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba436705d93698aeb457340a1d0786e
https://doi.org/10.1126/science.1084146
https://doi.org/10.1126/science.1084146
Autor:
Sandrine Humbert, Béé Edicte C. Charrin, Yohanns Bellaïche, Juliette D. Godin, Maria Molina-Calavita, Laurent Nguyen, Guy Keryer, Kelly Colombo, Diana Zala, Marie Laure Volvert, François Guillemot, Paula Dietrich, Ioannis Dragatsis, Frédéric Saudou
Publikováno v:
Neuron
Neuron, Elsevier, 2010, 67 (3), pp.392-406. ⟨10.1016/j.neuron.2010.06.027⟩
Neuron, Elsevier, 2010, 67 (3), pp.392-406. ⟨10.1016/j.neuron.2010.06.027⟩
SummaryHuntingtin is the protein mutated in Huntington's disease, a devastating neurodegenerative disorder. We demonstrate here that huntingtin is essential to control mitosis. Huntingtin is localized at spindle poles during mitosis. RNAi-mediated si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81551f9cbb819874411cf2f658c1f3e3
https://hal.archives-ouvertes.fr/hal-03373901
https://hal.archives-ouvertes.fr/hal-03373901
RIC-8 Is Required for GPR-1/2-Dependent Gα Function during Asymmetric Division of C. elegans Embryos
Autor:
David P. Siderovski, Christopher R. McCudden, Katayoun Afshar, Pierre Gönczy, Kelly Colombo, Christopher A. Johnston, Francis S. Willard
Publikováno v:
Cell. (2):219-230
Heterotrimeric G proteins are crucial for asymmetric cell division, but the mechanisms of signal activation remain poorly understood. Here, we establish that the evolutionarily conserved protein RIC-8 is required for proper asymmetric division of one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bbf8b00a79219a3d298e74ee5ebe82