Výsledky vyhledávání - "Kelly Carolina Frauzino Araújo"

Stereoselective biosynthesis of 3′-azido-3′-deoxythymidine 5′-O-β-D-ribopyranoside and in vitro evaluation as potential antileishmanial with in silicoADME prediction

Autor: Evilanna Lima Arruda, Elaine S. Nunes, Marina Clare Vinaud, Paula L. Melo de Souza, Valéria de Oliveira, Kelly Carolina Frauzino Araújo, Kamila B. Japiassu

Publikováno v: Process Biochemistry. 87:232-237

A stereoselective biosynthesis of a new 3′-azido-3′-deoxythymidine 5′-O-β-D-ribopyranoside (AZT-1) has been achieved from zidovudine (AZT) in PDSM medium, catalyzed by filamentous fungi Cunninghamela echinulata ATCC 9244 (16.6 mg/g, dry weigh/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb4eee4ac6499efb6e1e0136accecdee
https://doi.org/10.1016/j.procbio.2019.08.025

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Zidovudine Glycosylation by Filamentous Fungi Leads to a Better Redox Stability and Improved Cytotoxicity in B16F10 Murine Melanoma Cells

Autor: Luane Ferreira Garcia, Douglas Vieira Thomaz, Kamila B. Japiassu, Eric de Souza Gil, Marize Campos Valadares, Kelly Carolina Frauzino Araújo, Evilanna Lima Arruda, Valéria de Oliveira, Paula L. de Melo Souza, Alane Pereira Cortez

Publikováno v: Anti-cancer agents in medicinal chemistry. 20(14)

Background: The strategic development of therapeutic agents, capable of being targeted at their active sites, has been a major goal in treatment of cancer. The delivery of drugs for tumors has as its main challenge the development of safe and effecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec449a65f7a36527cd954fa1515921c
https://pubmed.ncbi.nlm.nih.gov/32329702

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