Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kelly C. Lane"'
Autor:
Falguni Basuli, Olga Vasalatiy, Jianfeng Shi, Kelly C. Lane, Freddy E. Escorcia, Rolf E. Swenson
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 480 (2024)
Desferrioxamine B (DFO) is the clinical standard chelator for preparing zirconium-89 labeled antibodies. In the current study, the stabilities of a zirconium-89 labeled panitumumab (PAN; Vectibix®) with three different chelators (DFO, DFO*, and DOTA
Externí odkaz:
https://doaj.org/article/1aa628e7299d4879ab489d3b3fd35fe8
Autor:
Elaine M. Jagoda, Falguni Basuli, Colleen Olkowski, Ido Weiss, Tim E. Phelps, Karen Wong, Anita Thien Ton, Kelly C. Lane, Steve Adler, Donna Butcher, Elijah F. Edmondson, Sol Langermann, Peter L. Choyke
Publikováno v:
Molecular Imaging, Vol 2023 (2023)
Objective. Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) is overexpressed in various cancers which has led to the development of therapeutic anti-Siglec-15 monoconal antibodies (mAbs). In these preclinical studies, the therapeutic mAb
Externí odkaz:
https://doaj.org/article/15ff0cb633964b33b41459e8b6efa45e
Autor:
Elaine M. Jagoda PhD, Olga Vasalatiy PhD, Falguni Basuli PhD, Ana Christina L. Opina PhD, Mark R. Williams BS, Karen Wong MS, Kelly C. Lane BS, Steve Adler PhD, Anita Thein Ton MS, Lawrence P. Szajek PhD, Biying Xu PhD, Donna Butcher BS, Elijah F. Edmondson DVM, PhD, Rolf E. Swenson PhD, John Greiner PhD, James Gulley MD, PhD, Janet Eary MD, Peter L. Choyke MD
Publikováno v:
Molecular Imaging, Vol 18 (2019)
Objective: The goal is to evaluate avelumab, an anti-PD-L1 monoclonal immunoglobulin G antibody labeled with zirconium-89 in human PD-L1-expressing cancer cells and mouse xenografts for clinical translation. Methods: [ 89 Zr]Zr-DFO-PD-L1 monoclonal a
Externí odkaz:
https://doaj.org/article/0683d49c84e0413591f8c7d2a2b91592
Autor:
Noriko Sato, Hisataka Kobayashi, Peter L. Choyke, Aki Furusawa, Ryuhei Okada, Biying C. Xu, Olga V. Vasalatiy, Kelly C. Lane, Colleen P. Olkowski, Yutaka Kurebayashi
Supplementary Materials and Methods, Table and Figures/Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58e56cc38bd3807734ce7b9ce2cdc3b
https://doi.org/10.1158/0008-5472.22430577.v1
https://doi.org/10.1158/0008-5472.22430577.v1
Autor:
Noriko Sato, Hisataka Kobayashi, Peter L. Choyke, Aki Furusawa, Ryuhei Okada, Biying C. Xu, Olga V. Vasalatiy, Kelly C. Lane, Colleen P. Olkowski, Yutaka Kurebayashi
Regulatory T cells (Tregs) are known to inhibit antitumor immunity, yet the specific mechanism by which intratumoral Tregs promote tumor growth remains unclear. To better understand the roles of intratumoral Tregs, we selectively depleted tumor-infil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1456673d3c505166241fbda2eac18908
https://doi.org/10.1158/0008-5472.c.6513648
https://doi.org/10.1158/0008-5472.c.6513648
Autor:
Anna Jean Wirth, Laura J. Gilbert, Carolyn M. Brown, Carolyn A. Edson, Lisa M. Landino, Nathan Grega-Larson, Kelly C. Lane
Publikováno v:
Analytical Biochemistry. 402:102-104
Numerous studies of S-glutathionylation of cysteine thiols indicate that this protein modification plays a key role in redox regulation of proteins. To facilitate the study of protein S-glutathionylation, we developed a synthesis and purification to
Publikováno v:
Free Radical Biology and Medicine. 49:S168