Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kelly C, Wade"'
Autor:
Sagori Mukhopadhyay, Jung-Jin Lee, Erica Hartman, Emily Woodford, Miren B. Dhudasia, Lisa M. Mattei, Scott G. Daniel, Kelly C. Wade, Mark A. Underwood, Kyle Bittinger
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
ABSTRACTAntibiotics are administered near-universally to very low birth weight (VLBW) infants after birth for suspected early-onset sepsis (EOS). We previously identified a phenotypic group of VLBW infants, referred to as low-risk for EOS (LRE), whos
Externí odkaz:
https://doaj.org/article/e1b1298cc6734a96a58ad944a3a5fb33
Autor:
Jacqueline G. Gerhart, Kevin M. Watt, Andrea Edginton, Kelly C. Wade, Sara N. Salerno, Daniel K. Benjamin Jr, P. Brian Smith, Christoph P. Hornik, Michael Cohen‐Wolkowiez, Shahnaz Duara, Ashley Ross, Karen Shattuck, Dan L. Stewart, Natalie Neu, Daniel Gonzalez, the Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 7, Pp 500-510 (2019)
Fluconazole is used to treat hematogenous Candida meningoencephalitis in preterm and term infants. To characterize plasma and central nervous system exposure, an adult fluconazole physiologically‐based pharmacokinetic (PBPK) model was scaled to inf
Externí odkaz:
https://doaj.org/article/7d2b1a51f05e4740a751175400d3d625
Autor:
Sagori, Mukhopadhyay, Hannah L, Itell, Erica, Hartman, Emily, Woodford, Miren B, Dhudasia, Justin T, Steppe, Sarah, Valencia, Hunter, Roark, Kelly C, Wade, Kristin E D, Weimer, Sallie R, Permar, Karen M, Puopolo
Publikováno v:
Pediatric Infectious Disease Journal. 41:904-910
The optimal approach to managing postnatal cytomegalovirus disease (pCMV) among very low birth weight (VLBW) infants remains unknown. Methods to facilitate screening are needed.Determine whether mother's milk and infant saliva can be used to reliably
Autor:
Norma Terrin, Tamorah R Lewis Md PhD, Jonathan M. Davis, Thomas Salaets, Kurt Michels, Kelly C. Wade
Publikováno v:
Journal of Perinatology
Objective The Neonatal Adverse Event Severity Scale (NAESS) was developed to improve scoring of neonatal adverse events (AEs) and accelerate neonatal drug development. This is the first validation study of the novel tool. Study design Retrospective v
Autor:
Daniel K. Benjamin, Michael Cohen-Wolkowiez, Kelly C. Wade, Jennifer Le, Rachel G. Greenberg, YoungJun Yoo, Kanecia O. Zimmerman
Publikováno v:
J Pediatric Infect Dis Soc
BackgroundPremature, very low birth weight (VLBW) neonates are at risk for early-onset sepsis and receive ampicillin and gentamicin post-birth. Antimicrobial stewardship supports short-course antibiotics, but how long antibiotic concentrations remain
Autor:
Rachel G. Greenberg, Kelly C. Wade, Reese H. Clark, Morgan England, P. Brian Smith, Michael Cohen-Wolkowiez, Ashley Stark, Matthew M. Laughon, Julie Childers, Daniel K. Benjamin
Publikováno v:
Pediatric Infectious Disease Journal. 39:713-717
BACKGROUND We sought to compare meropenem and fluconazole dosing in the neonatal intensive care unit with recommendations based on published pharmacokinetic (PK) studies in infants. METHODS We performed an observational cohort study of infants
Autor:
Dustin D. Flannery, Alvaro Zevallos Barboza, Kelly C. Wade, Madeline R. Pfeifer, Jeffrey S. Gerber, Jeffrey S. Morris, Karen M. Puopolo
Publikováno v:
JAMA. 329:682
This observational study explores whether rubella serostatus, which is routinely assessed during pregnancy, can serve as a proxy for measles serostatus in parturient persons.
Autor:
Jennifer, Le, Rachel G, Greenberg, YoungJun, Yoo, Reese H, Clark, Daniel K, Benjamin, Kanecia O, Zimmerman, Michael, Cohen-Wolkowiez, Kelly C, Wade
Publikováno v:
Journal of perinatology : official journal of the California Perinatal Association. 42(7)
Define optimal ampicillin dosing for empiric early-onset sepsis (EOS) therapy in preterm neonates.We simulated ampicillin concentrations in newborns (birthweight 1500 g; gestational age 22-27 weeks), summarizing three 48 h regimens: high 100 mg/kg Q8
Publikováno v:
Clin Perinatol
Antimicrobial medications are the most commonly used medications in the neonatal intensive care unit. Antibiotics are used for infection prophylaxis, empiric treatment, and definitive treatment of confirmed infection. The choice of medication should
Autor:
Kelly C. Wade, Dustin D. Flannery
Publikováno v:
Clinics in perinatology. 48(2)
Premature infants admitted to the neonatal intensive care unit are at risk for severe infections and infectious complications caused by vaccine-preventable diseases. Both maternal and neonatal vaccination prevent such infections and improve outcomes