Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kelly C, Falls"'
Autor:
Jeffrey M. Stolwijk, Kelly C. Falls-Hubert, Charles C. Searby, Brett A. Wagner, Garry R. Buettner
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Selenium is a metalloid trace element essential for maintaining the optimal redox environment in cells and tissues. It is structurally incorporated into over 25 selenoproteins and enzymes. The glutathione peroxidase (GPx) family of enzymes has a crit
Externí odkaz:
https://doaj.org/article/1b2fc01eca9e48348aadcd66a1d7a495
Autor:
Kristin E. Brandt, Kelly C. Falls, Joshua D. Schoenfeld, Samuel N. Rodman, Zhimin Gu, Fenghuang Zhan, Joseph J. Cullen, Brett A. Wagner, Garry R. Buettner, Bryan G. Allen, Daniel J. Berg, Douglas R. Spitz, Melissa A. Fath
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 82-87 (2018)
Pharmacological doses (> 1Â mM) of ascorbate (a.k.a., vitamin C) have been shown to selectively kill cancer cells through a mechanism that is dependent on the generation of H2O2 at doses that are safely achievable in humans using intravenous adminis
Externí odkaz:
https://doaj.org/article/959fae2b285c4504aa4c9bdc7bfe028d
Autor:
Joseph J. Cullen, Prabhat C. Goswami, Garry R. Buettner, Douglas R. Spitz, Rory S. Carroll, Matthew S. Alexander, Kelly C. Falls-Hubert, Jeffrey M. Stolwijk, Brett A. Wagner, Amanda L. Kalen, Ehab H. Sarsour, Juan Du, Brianne R. O'Leary, Adrienne R. Gibson
Increased DUOX1 and DUOX2 expression is reversed by catalase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b0fdf5c148f28e98783a64f7bb5f89
https://doi.org/10.1158/0008-5472.22424608
https://doi.org/10.1158/0008-5472.22424608
Autor:
Dawn E. Quelle, Benjamin W. Darbro, James R. Howe, Andrew M. Bellizzi, Thomas M. O'Dorisio, Scott K. Sherman, Ryan W. Askeland, Heather J. Major, Aloysius J. Klingelhutz, Francoise A. Gourronc, Frederick W. Quelle, Agshin F. Taghiyev, Sara M. Reed, Kelly C. Falls, Viviane P. Muniz, Jussara Hagen
Figure S2. Representative IPA mechanistic network for signaling regulators predicted to contribute to the RABL6A knockdown phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb316efa37fe042ca5e2c480aebbbc9
https://doi.org/10.1158/0008-5472.22404263.v1
https://doi.org/10.1158/0008-5472.22404263.v1
Autor:
Dawn E. Quelle, Benjamin W. Darbro, James R. Howe, Andrew M. Bellizzi, Thomas M. O'Dorisio, Scott K. Sherman, Ryan W. Askeland, Heather J. Major, Aloysius J. Klingelhutz, Francoise A. Gourronc, Frederick W. Quelle, Agshin F. Taghiyev, Sara M. Reed, Kelly C. Falls, Viviane P. Muniz, Jussara Hagen
Table S1. List of differentially regulated genes caused by RABL6A knockdown (KD), relative to control (CON), in BON-1 PNET cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b710410caa0071f21f915ebf926f36c
https://doi.org/10.1158/0008-5472.22404248.v1
https://doi.org/10.1158/0008-5472.22404248.v1
Autor:
Jeffrey M. Stolwijk, Ann Tomanek-Chalkley, Mengshi Li, Samuel N. Rodman, Michael L. McCormick, Garry R. Buettner, Kelly C. Falls-Hubert, Michael K. Schultz, Michael G. Anderson, Val C. Sheffield, Bryan G. Allen, Kai Gui, Shane R. Solst, Brian Wels, Hartmut Schmidt, Vanessa Sandfort, Aimee L. Butler, Douglas R. Spitz, Charles Searby
Publikováno v:
Free Radic Biol Med
Therapy for lung cancer patients includes surgery, radiation, and chemotherapy. While treatments initially illicit desirable responses, the presence of hypoxia and drug resistant cells within tumors ultimately lead to treatment failure. Disulfiram (D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65c8554684b8c1f0fef9cb3cd4f0ee2
https://doi.org/10.1016/j.freeradbiomed.2020.01.186
https://doi.org/10.1016/j.freeradbiomed.2020.01.186
Autor:
Collin D. Heer, Andrew B. Davis, David B. Riffe, Brett A. Wagner, Kelly C. Falls, Bryan G. Allen, Garry R. Buettner, Robert A. Beardsley, Dennis P. Riley, Douglas R. Spitz
Publikováno v:
Antioxidants, Vol 7, Iss 1, p 18 (2018)
Lung cancer, together with head and neck cancer, accounts for more than one-fourth of cancer deaths worldwide. New, non-toxic therapeutic approaches are needed. High-dose IV vitamin C (aka, pharmacological ascorbate; P-AscH−) represents a promising
Externí odkaz:
https://doaj.org/article/ceb651bc27ea41a49bd9dd8355de159b
Autor:
Calvin S. Carter, Sunny C. Huang, Charles C. Searby, Benjamin Cassaidy, Michael J. Miller, Wojciech J. Grzesik, Ted B. Piorczynski, Thomas K. Pak, Susan A. Walsh, Michael Acevedo, Qihong Zhang, Kranti A. Mapuskar, Ginger L. Milne, Antentor O. Hinton Jr., Deng-Fu Guo, Robert Weiss, Kyle Bradberry, Eric B. Taylor, Adam J. Rauckhorst, David W. Dick, Vamsidhar Akurathi, Kelly C. Falls-Hubert, Brett A. Wagner, Walter A. Carter, Kai Wang, Andrew W. Norris, Kamal Rahmouni, Garry R. Buettner, Jason M. Hansen, Douglas R. Spitz, E. Dale Abel, Val C. Sheffield
Publikováno v:
Am J Physiol Endocrinol Metab
Carter et al. report that exposure to static magnetic and electric fields (sBE), for as little as 3 days, reverses glucose intolerance and insulin resistance in diet-induced and genetic mouse models of type 2 diabetes (1). They hypothesize that sBE t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1386b72a2e48b46c9d8fea7c7e1a7f1e
https://pubmed.ncbi.nlm.nih.gov/33843279
https://pubmed.ncbi.nlm.nih.gov/33843279
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88159 (2014)
Metabolic engineers strive to improve the production yields of microbial fermentations, sometimes by mutating the genomes of production strains. Some mutations are detrimental to the health of the organism, so a quantitative and mechanistic understan
Externí odkaz:
https://doaj.org/article/fa6cc62c209340c98b354bd30b6dbd0b