Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kelly Bouchonville"'
Autor:
Carrie Ketel, Helen S W Wang, Mark McClellan, Kelly Bouchonville, Anna Selmecki, Tamar Lahav, Maryam Gerami-Nejad, Judith Berman
Publikováno v:
PLoS Genetics, Vol 5, Iss 3, p e1000400 (2009)
Centromeres are critically important for chromosome stability and integrity. Most eukaryotes have regional centromeres that include long tracts of repetitive DNA packaged into pericentric heterochromatin. Neocentromeres, new sites of functional kinet
Externí odkaz:
https://doaj.org/article/6be9eec96c154723b8b9088be27743f9
Autor:
Ting Zhang, Alisa Ambrodji, Huixing Huang, Kelly Bouchonville, Amy Etheridge, Remington Schmidt, Jose Cardiel Nunez, Zoey Temesgen, Federico Innocenti, Robert Diasio, Carlo Largiadèr, Steven M. Offer
Publikováno v:
Cancer Research. 82:5420-5420
Genetic variants in the DPYD gene that are deleterious to dihydropyrimidine dehydrogenase (DPD) enzyme function have demonstrated clinical validity as predictive biomarkers for severe (i.e., CTCAE grade ≥3) and potentially lethal toxicity to fluoro
Autor:
Huixing Huang, Dominic Schaerer, Remington Schmidt, Ting Zhang, Tanja K Froehlich, Kelly Bouchonville, Robert B Diasio, Ursula Amstutz, Carlo Largiadèr, Steven M Offer
Publikováno v:
Cancer Research. 82:5805-5805
The primary mechanism of action for the chemotherapeutic 5-fluorouracil (5-FU) is inhibition of thymidylate synthase (TS), which leads to nucleotide imbalance and subsequent cellular death. Expression of TS has been suggested to be determined by a va
Autor:
Encarnación Andaluz, Alberto Bellido, Kelly Bouchonville, Germán Larriba, Judith Berman, Jonathan Gómez-Raja, Anna Selmecki, Richard Calderone
Publikováno v:
Molecular Microbiology. 79:1462-1482
RAD52 is required for almost all recombination events in Saccharomyces cerevisiae. We took advantage of the heterozygosity of HIS4 in the Candida albicans SC5314 lineage to study the role of Rad52 in the genomic stability of this important fungal pat
Publikováno v:
Eukaryotic Cell. 8:1554-1566
Candida albicans strains tolerate aneuploidy, historically detected as karyotype alterations by pulsed-field gel electrophoresis and more recently revealed by array comparative genome hybridization, which provides a comprehensive and detailed descrip
Autor:
Tamar Lahav, Anna Selmecki, Kelly Bouchonville, Carrie S. Ketel, Maryam Gerami-Nejad, Mark R McClellan, Helen Wang, Judith Berman
Publikováno v:
PLoS Genetics, Vol 5, Iss 3, p e1000400 (2009)
PLoS Genetics
PLoS Genetics
Centromeres are critically important for chromosome stability and integrity. Most eukaryotes have regional centromeres that include long tracts of repetitive DNA packaged into pericentric heterochromatin. Neocentromeres, new sites of functional kinet
Publikováno v:
Journal of Cell Science. 121:724-724
Candida albicans, the most prevalent fungal pathogen of humans, grows with multiple morphologies. The dynamics of nuclear movement are similar in wild-type yeast and pseudohyphae: nuclei divide across the bud neck. By contrast, in hyphae, nuclei migr