Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kelly Blaine"'
Autor:
Jorge E Gomez Medellin, Maile Kananiokala Hollinger, Jillian Rosenberg, Kelly Blaine, Trevin Kurtanich, Nick Ankenbruck, Cara Lynn Hrusch, Anne I Sperling, Melody A Swartz
Publikováno v:
The Journal of Immunology. 208:109.24-109.24
Asthmatic lung samples present with both a higher density of pulmonary lymphatic vessels and a higher incidence of bronchus associated lymphoid tissue (BALT). Here, we asked whether lymphangiogenesis, stimulated by the VEGF-C/VEGFR-3 signaling axis i
Autor:
Young me Yoon, Tania Velez, Vaibhav Upadhyay, Sara Vazquez, Cathryn T Lee, Kelly Blaine, Donna Decker, Robert Guzy, Ayodeji Adegunsoye, Mary Strek, Imre Noth, Mark S Anderson, Joseph DeRisi, Anthony Shum, Anne I Sperling
Publikováno v:
The Journal of Immunology. 208:48.01-48.01
Interstitial lung disease (ILD), a group of disorders characterized by scarring of the lungs, often leads to fatal impairment of respiratory function. While some patients exhibit features of autoimmunity, the role of the immune system within this het
Publikováno v:
Proceedings of the National Academy of Sciences. 101:9351-9356
Although both naive and effector T lymphocytes interact with antigen-expressing cells, the functional outcome of these interactions is distinct. Naive CD8 + T cells are activated to proliferate and differentiate into effector cytolytic T lymphocytes
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1681-1690
Background: Disruption of the growth hormone (GH) axis by maternal ethanol (ETOH) consumption may contribute to abnormalities in offspring. Interestingly, γ-aminobutyric acid (GABA) neurotransmission, which is vulnerable to fetal ETOH exposure, also
Autor:
Cara Hrusch, Joshua Casaos, Catherine Bonham, Kelly Blaine, Dana Bryazka, Mohammad Jaffery, Stephenie Takahashi, Imre Noth, Anne Sperling
Publikováno v:
The Journal of Immunology. 194:52.13-52.13
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing irreversible lung scarring and loss of pulmonary function. RNA analysis has shown that patients with IPF have reduced ICOS expression in peripheral blood mononuclear cells. We
Publikováno v:
The Journal of Immunology. 192:118.7-118.7
Dendritic cells (DCs) play a critical role in the development of Th2 responses during atopic asthma, but the mechanism by which allergens drive DCs to promote Th2 responses is still unclear. Previously, we demonstrated that allergen-specific IgG immu
Publikováno v:
The Journal of Immunology. 192:184.28-184.28
The role of the adaptive immune response in idiopathic pulmonary fibrosis (IPF) has been an area of debate. Several studies have shown that patients with IPF had increased numbers of T cells in their lungs, suggesting that these cells may play a role
Publikováno v:
The Journal of Immunology. 192:118.12-118.12
Low serum levels of vitamin D (VD3) have been implicated in multiple immune disorders including atopic asthma. Other studies have shown that VD3 promotes monocyte-derived dendritic cell (MDDC) differentiation into tolerogenic DCs, which in turn induc
Publikováno v:
Alcoholism, clinical and experimental research. 21(5)
This study was designed to examine the effect of fetal ethanol (ETOH) exposure on the sensitivity of the hypothalamic-growth hormone (GH) axis to clonidine (an alpha 2-adrenoreceptor agonist) stimulation and GH feedback. During gestation, dams were f
Publikováno v:
The Journal of Immunology. 188:54.7-54.7
IPF is an interstitial lung disease that affects over 128,000 people in the U.S., has a yearly mortality of 48,000, and has no effective treatment. Current theories on the etiology of IPF have not focused on the role of the immune system due to the i