Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation.

Autor: Andrée-Anne Grosset, Frédérick Dallaire, Tien Nguyen, Mirela Birlea, Jahg Wong, François Daoust, Noémi Roy, André Kougioumoutzakis, Feryel Azzi, Kelly Aubertin, Samuel Kadoury, Mathieu Latour, Roula Albadine, Susan Prendeville, Paul Boutros, Michael Fraser, Rob G Bristow, Theodorus van der Kwast, Michèle Orain, Hervé Brisson, Nazim Benzerdjeb, Hélène Hovington, Alain Bergeron, Yves Fradet, Bernard Têtu, Fred Saad, Frédéric Leblond, Dominique Trudel

Publikováno v: PLoS Medicine, Vol 17, Iss 8, p e1003281 (2020)

BACKGROUND:Prostate cancer (PC) is the most frequently diagnosed cancer in North American men. Pathologists are in critical need of accurate biomarkers to characterize PC, particularly to confirm the presence of intraductal carcinoma of the prostate

Externí odkaz: https://doaj.org/article/8fcceac90c674478ae01e4c367277d85

Data from Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy

Autor: Kevin Petrecca, Frederic Leblond, Marie-Christine Guiot, Eric Marple, Jason Karamchandiani, Kirk Urmey, Joannie Desroches, Kelly Aubertin, Jeanne Mercier, Michael Jermyn

Effectiveness of surgery as a cancer treatment is reduced when all cancer cells are not detected during surgery, leading to recurrences that negatively impact survival. To maximize cancer cell detection during cancer surgery, we designed an in situ i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f23786ca445c7b35b679610e945bd712
https://doi.org/10.1158/0008-5472.c.6509148.v1

Applications thérapeutiques des vésicules extracellulaires

Autor: Kelly Aubertin, Max Piffoux, Anna Sebbagh, Jeanne Gauthier, Amanda K.A. Silva, Florence Gazeau

Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2021, 37 (12), pp.1146-1157. ⟨10.1051/medsci/2021207⟩

International audience; Les vésicules extracellulaires, sécrétées spontanément ou en réponse à un stress par tous les types cellulaires, sont proposés comme des biothérapies alternatives aux thérapies cellulaires et aux nanomédicaments syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d275790937d8a3d479e9dadaf080713a
https://doi.org/10.1051/medsci/2021207

SERS tags derived from silver nanoparticles and aryl diazonium salts for cell Raman imaging

Autor: Da Li, Philippe Nizard, Delphine Onidas, Aazdine Lamouri, Jean Pinson, Samia Mahouche-Chergui, Kelly Aubertin, Florence Gazeau, Yun Luo, Claire Mangeney

Publikováno v: Nanoscale
Nanoscale, Royal Society of Chemistry, In press, ⟨10.1039/D1NR03148A⟩
Nanoscale, Royal Society of Chemistry, 2022, 14 (4), pp.1452-1458. ⟨10.1039/D1NR03148A⟩

International audience; The surface functionalization of silver nanoparticles (NPs) by Raman reporters has stimulated a wide interest in recent years for the design of Surface-Enhanced Raman Spectroscopy (SERS) labels. However, silver NPs are prone t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8795b9afbd583804941a59509b236e1b
https://pubmed.ncbi.nlm.nih.gov/35018945

Development of extracellular vesicle-based medicinal products: A position paper of the group 'Extracellular Vesicle translatiOn to clinicaL perspectiVEs – EVOLVE France'

Autor: Emilie Velot, Marina Trouillas, Joël Chopineau, J. Peltzer, Sophie Brouard, Olivier Favre-Bulle, Jérôme Larghero, Tristan Montier, Amanda K. A. Silva, Florence Gazeau, Phlippe Mauduit, Jean-Hugues Trouvin, Arnaud Bianchi, Noëlle Mathieu, Christian Jorgensen, Matti Ullah, Kelly Aubertin, Philippe Menasché, Surendar Arumugam, Jolanda Spadavecchia, C. Aussel, Danièle Noël, Wilfrid Boireau, M. Dedier, Sébastien Jauliac, Sébastien Banzet, Jean-Marie Bach, Antoine Monsel, Max Piffoux, Kondareddy Cherukula, Marie Morille, Célia Ravel, Christophe Martinaud, Chantal M. Boulanger, Claire Wilhelm, Mathilde Mosser, Olivier Blanc-Brude, Nicolas Sailliet, Pierre-Emmanuel Rautou, Nathalie Luciani, Isabelle Raymond-Letron, Céline Elie-Caille, Gabriel Rahmi, Anna C. Sebbagh

Publikováno v: Advanced Drug Delivery Reviews
Advanced Drug Delivery Reviews, Elsevier, 2021, 179, pp.114001. ⟨10.1016/j.addr.2021.114001⟩
Advanced Drug Delivery Reviews, 2021, 179, pp.114001. ⟨10.1016/j.addr.2021.114001⟩

International audience; Extracellular vesicles (EV) are emergent therapeutic effectors that have reached clinical trial investigation. To translate EV-based therapeutic to clinic, the challenge is to demonstrate quality, safety, and efficacy, as requ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607492892c07dcbf68c27bb32eea9b55
https://hal.archives-ouvertes.fr/hal-03412034