Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kelly Aparecida Geraldo, Yoneyama"'
Autor:
Débora Cristina de Oliveira Silva Nunes, Mônica Soares Costa, Luiz Borges Bispo-da-Silva, Eloísa Amália Vieira Ferro, Mariana Alves Pereira Zóia, Luiz Ricardo Goulart, Renata Santos Rodrigues, Veridiana de Melo Rodrigues, Kelly Aparecida Geraldo Yoneyama
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 117 (2022)
BACKGROUND Leishmania parasites cause leishmaniasis that range from self-limiting cutaneous lesions to more serious forms of the disease. The search for potential drug targets focusing on biochemical and metabolic pathways revealed the sterol biosynt
Externí odkaz:
https://doaj.org/article/e0d0dd2f0176485db6a161b67876c082
Autor:
Denise Oliveira Guimarães, Milene Ferro, Thamires Silva Santos, Tassia Rafaela Costa, Kelly Aparecida Geraldo Yoneyama, Veridiana de Melo Rodrigues, Flávio Henrique-Silva, Renata Santos Rodrigues
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 223
The genus Odontomachus is widely distributed in neotropical areas throughout Central and South America. It is a stinging ant that subdues its prey (insects) by injecting them a cocktail of toxic molecules (venom). Ant venoms are generally composed of
Autor:
Vitor de Freitas, Tássia Rafaella Costa, Amanda Rodrigues Nogueira, Lorena Polloni, Thales Alves de Melo Fernandes, Lucas Ian Veloso Correia, Bruna Cristina Borges, Samuel Cota Teixeira, Marcelo José Barbosa Silva, Fernanda Gobbi Amorim, Loïc Quinton, André Lopes Saraiva, Foued Salmen Espindola, Leo Kei Iwai, Renata Santos Rodrigues, Kelly Aparecida Geraldo Yoneyama, Veridiana de Melo Rodrigues Ávila
Publikováno v:
Toxicon. 230:107156
Autor:
Débora Cristina de Oliveira Nunes, Luiz Borges Bispo-da-Silva, Danielle Reis Napolitano, Mônica Soares Costa, Márcia Moura Nunes Rocha Figueira, Renata Santos Rodrigues, Veridiana de Melo Rodrigues, Kelly Aparecida Geraldo Yoneyama
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180530 (2017)
Leishmaniasis is a group of diseases caused by protozoa of Leishmania genus. The currently available treatments for this disease are expensive, present high toxicity and are associated to difficulties of healing and parasite resistance. Therefore, th
Externí odkaz:
https://doaj.org/article/c3dddf36bec94ff382efe954ab461b95
Autor:
Mariana Sant'Anna Pereira, Nicolau, Milllena Almeida, Resende, Pedro, Serafim, Germano Yoneda Pereira, Lima, Carlos, Ueira-Vieira, Nilson, Nicolau-Junior, Kelly Aparecida Geraldo, Yoneyama
Publikováno v:
Journal of biomolecular structuredynamics.
Malaria is a neglected parasitic infection of global importance. It is mainly present in tropical countries and caused by a protozoa that belongs to the genus
Autor:
Francis Barbosa Ferreira, Mário Sérgio Rocha Gomes, Dayane Lorena Naves de Souza, Sarah Natalie Cirilo Gimenes, Letícia Eulalio Castanheira, Márcia Helena Borges, Renata Santos Rodrigues, Kelly Aparecida Geraldo Yoneyama, Maria Inês Homsi Brandeburgo, Veridiana M. Rodrigues
Publikováno v:
Toxins, Vol 5, Iss 12, Pp 2403-2419 (2013)
In this work, we describe the molecular cloning and pharmacological properties of an acidic phospholipase A2 (PLA2) isolated from Bothrops pauloensis snake venom. This enzyme, denominated BpPLA2-TXI, was purified by four chromatographic steps and rep
Externí odkaz:
https://doaj.org/article/2d0a712fdb884eec9dc45bc50528b79b
Autor:
Mariana Sant’Anna Pereira Nicolau, Milllena Almeida Resende, Pedro Serafim, Germano Yoneda Pereira Lima, Carlos Ueira-Vieira, Nilson Nicolau-Junior, Kelly Aparecida Geraldo Yoneyama
Malaria is a neglected parasitic infection of global importance. It is mainly present in tropical countries and caused by a protozoa that belongs to the genus Plasmodium. The disease vectors are female Anopheles mosquitoes infected with the Plasmodiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fd2c1d2e13346553957d66ead46f87
Autor:
Daiana Silva Lopes, Fernanda Van Petten de Vasconcelos Azevedo, Mariana Alves Pereira Zóia, Kelly Aparecida Geraldo Yoneyama, Luiz Ricardo Goulart, Lara Vecchi, Veridiana M. Rodrigues, Patrícia Terra Alves, Sarah Natalie Cirilo Gimenes, Anielle Christine Almeida Silva, Renata Santos Rodrigues
Publikováno v:
International Journal of Biological Macromolecules. 135:261-273
This work shows the antitumor and antimetastatic effects of BthTX-II, an Asp-49 PLA2 from Bothrops jararacussu venom, on MDA-MB-231 human triple negative breast cancer cells. BthTX-II caused a dose-dependent cell death of MDA-MB-231 cells when compar
Autor:
Veridiana M. Rodrigues, Bruna Cristina Borges, Daiana Silva Lopes, Yasmim Garcia Gonçalves, Marcelo José Barbosa Silva, Kelly Aparecida Geraldo Yoneyama, Claudio Vieira da Silva, Renata Santos Rodrigues, Gustavo Von Poelhsitz, Marcelo Santos da Silva, Mônica Soares Costa, Débora Cristina de Oliveira Nunes, Samuel Cota Teixeira
Publikováno v:
Journal of Inorganic Biochemistry. 195:1-12
Some metallodrugs that exhibit interesting biological activity contain transition metals such as ruthenium, and have been extensively exploited because of their antiparasitic potential. In previous study, we reported the remarkable anti-Leishmania ac
Autor:
Débora Cristina de Oliveira Silva Nunes, Mônica Soares Costa, Luiz Borges Bispo-da-Silva, Eloísa Amália Vieira Ferro, Mariana Alves Pereira Zóia, Luiz Ricardo Goulart, Renata Santos Rodrigues, Veridiana de Melo Rodrigues, Kelly Aparecida Geraldo Yoneyama
Publikováno v:
Memórias do Instituto Oswaldo Cruz, Volume: 117, Article number: e210157, Published: 29 APR 2022
BACKGROUND Leishmania parasites cause leishmaniasis that range from self-limiting cutaneous lesions to more serious forms of the disease. The search for potential drug targets focusing on biochemical and metabolic pathways revealed the sterol biosynt