Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kelly A. Vranich"'
Publikováno v:
Molecular Biology of the Cell. 16:3620-3631
Actin filament bundles can shape cellular extensions into dramatically different forms. We examined cytoskeleton formation during wing hair morphogenesis using both confocal and electron microscopy. Hairs elongate with linear kinetics (approximately
Autor:
Linda Ruggiero, Kelly A. Vranich, David J. DeRosier, Patricia S. Connelly, Lewis G. Tilney, Gregory M. Guild
Publikováno v:
Molecular Biology of the Cell. 15:5481-5491
Drosophila bristles display a precise orientation and curvature. An asymmetric extension of the socket cell overlies the newly emerging bristle rudiment to provide direction for bristle elongation, a process thought to be orchestrated by the nerve de
Publikováno v:
Molecular Biology of the Cell. 14:3953-3966
Drosophila bristle cells are shaped during growth by longitudinal bundles of cross-linked actin filaments attached to the plasma membrane. We used confocal and electron microscopy to examine actin bundle structure and found that during bristle elonga
Publikováno v:
The Journal of Cell Biology
The actin bundles essential for Drosophila bristle elongation are hundreds of microns long and composed of cross-linked unipolar filaments. These long bundles are built from much shorter modules that graft together. Using both confocal and electron m
Autor:
James R. Bartles, Gabriela Sekerková, Enrico Mugnaini, Lili Zheng, Kelly A. Vranich, Lewis G. Tilney
Publikováno v:
Cell. 102:377-385
The espins are actin-bundling proteins of brush border microvilli and Sertoli cell-spermatid junctions. We have determined that espins are also present in hair cell stereocilia and have uncovered a connection between the espin gene and jerker, a rece
Publikováno v:
Journal of Cell Science. 113:1255-1265
Developing bristles in Drosophila pupae contain 7–11 bundles of crosslinked actin filaments and a large population of microtubules. During bristle growth the rate of cell elongation increases with bristle length. Thin section EM shows that bundle s
Publikováno v:
The Journal of Cell Biology
Previous studies demonstrate that in developing Drosophila bristles, two cross-linking proteins are required sequentially to bundle the actin filaments that support elongating bristle cells. The forked protein initiates the process and facilitates su
Publikováno v:
The Journal of Cell Biology
In developing Drosophila bristles two species of cross-linker, the forked proteins and fascin, connect adjacent actin filaments into bundles. Bundles form in three phases: (a) tiny bundles appear; (b) these bundles aggregate into larger bundles; and
Publikováno v:
Journal of experimental zoology. Part A, Comparative experimental biology. 303(11)
Trichuris muris is a large metazoan pathogen that has been proposed to live intracellularly within living host intestinal epithelial cells. We sought to determine how Trichuris bores its way through the mucosal epithelium and to elucidate the parasit
Publikováno v:
Journal of cell science. 115(Pt 3)
Drosophila bristle cells form enormous extensions that are supported by equally impressive scaffolds of modular, polarized and crosslinked actin filament bundles. As the cell matures and support is taken over by the secreted cuticle, the actin scaffo