Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Kelly A. Volcik"'
Autor:
Khanh N Vu, Christie M Ballantyne, Ron C Hoogeveen, Vijay Nambi, Kelly A Volcik, Eric Boerwinkle, Alanna C Morrison
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148765 (2016)
INTRODUCTION:Health benefits of low-to-moderate alcohol consumption may operate through an improved lipid profile. A Mendelian randomization (MR) approach was used to examine whether alcohol consumption causally affects lipid levels. METHODS:This ana
Externí odkaz:
https://doaj.org/article/2f1bc720506444f689d004664a4a7b1f
Autor:
Tingting Weng, Fayong Luo, Brian A. Bruckner, S. Jyothula, Cory Wilson, Leng Han, Kelly A. Volcik, Rajarajan Amirthalingam Thandavarayan, Harry Karmouty-Quintana, Wei Li, Jingjing Huang, Yu Xiang, Chioniso P. Masamha, Michael R. Blackburn, Lei Li, Zheng Xia, Eric J. Wagner, Tinne C.J. Mertens, Shervin Assassi, Junsuk Ko, Ning Yuan Chen, Jonathan Davies, Scott D. Collum, Kemly Philip, Jose G. Molina
Publikováno v:
Journal of Clinical Investigation. 129:1984-1999
Idiopathic pulmonary fibrosis (IPF) is a chronic and deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) by myofibroblasts is a key factor that drives disease pathogenesis, althoug
Autor:
Kiran Musunuru, Simon P R Romaine, Guillaume Lettre, James G Wilson, Kelly A Volcik, Michael Y Tsai, Herman A Taylor, Pamela J Schreiner, Jerome I Rotter, Stephen S Rich, Susan Redline, Bruce M Psaty, George J Papanicolaou, Jose M Ordovas, Kiang Liu, Ronald M Krauss, Nicole L Glazer, Stacey B Gabriel, Myriam Fornage, L Adrienne Cupples, Sarah G Buxbaum, Eric Boerwinkle, Christie M Ballantyne, Sekar Kathiresan, Daniel J Rader
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36473 (2012)
BACKGROUND:Whereas it is well established that plasma lipid levels have substantial heritability within populations, it remains unclear how many of the genetic determinants reported in previous studies (largely performed in European American cohorts)
Externí odkaz:
https://doaj.org/article/b69fbaf6cc094614b86704664ba2f718
Autor:
Clara C Elbers, Yiran Guo, Vinicius Tragante, Erik P A van Iperen, Matthew B Lanktree, Berta Almoguera Castillo, Fang Chen, Lisa R Yanek, Mary K Wojczynski, Yun R Li, Bart Ferwerda, Christie M Ballantyne, Sarah G Buxbaum, Yii-Der Ida Chen, Wei-Min Chen, L Adrienne Cupples, Mary Cushman, Yanan Duan, David Duggan, Michele K Evans, Jyotika K Fernandes, Myriam Fornage, Melissa Garcia, W Timothy Garvey, Nicole Glazer, Felicia Gomez, Tamara B Harris, Indrani Halder, Virginia J Howard, Margaux F Keller, M Ilyas Kamboh, Charles Kooperberg, Stephen B Kritchevsky, Andrea LaCroix, Kiang Liu, Yongmei Liu, Kiran Musunuru, Anne B Newman, N Charlotte Onland-Moret, Jose Ordovas, Inga Peter, Wendy Post, Susan Redline, Steven E Reis, Richa Saxena, Pamela J Schreiner, Kelly A Volcik, Xingbin Wang, Salim Yusuf, Alan B Zonderland, Sonia S Anand, Diane M Becker, Bruce Psaty, Daniel J Rader, Alex P Reiner, Stephen S Rich, Jerome I Rotter, Michèle M Sale, Michael Y Tsai, Ingrid B Borecki, Robert A Hegele, Sekar Kathiresan, Michael A Nalls, Herman A Taylor, Hakon Hakonarson, Suthesh Sivapalaratnam, Folkert W Asselbergs, Fotios Drenos, James G Wilson, Brendan J Keating
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50198 (2012)
Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of ∼2,000 candi
Externí odkaz:
https://doaj.org/article/61a34aa47fe44caabf48c32acc494970
Autor:
Michael R. Blackburn, Jingjing Huang, Maureen D. Mayes, Minghua Wu, Jose G. Molina, Nancy Wareing, Tingting Weng, Kelly A. Volcik, Leng Han, Junsuk Ko, Ning Yuan Chen, Ping Ji, Yu Xiang, Eric J. Wagner, Shervin Assassi
Publikováno v:
The Journal of Experimental Medicine
This study implicates the key regulator of alternative polyadenylation, CFIm25 in dermal fibrosis and in systemic sclerosis (scleroderma) pathogenesis. CFIm25 downregulation promotes the expression of profibrotic factors, exaggerates bleomycin-induce
Autor:
Fayong Luo, Lavannya M. Pandit, Javier Amione-Guerra, Tingting Weng, Harry Karmouty-Quintana, Michael R. Blackburn, Kelly A. Volcik, Brian A. Bruckner, Matthias Loebe, Kemly Philip, Ernestina Melicoff, Holger K. Eltzschig, R.R. Bunge, Jonathan Davies, Luis J. Garcia-Morales, Ning Yuan Chen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:574-583
Group III pulmonary hypertension (PH) is a highly prevalent and deadly lung disorder with limited treatment options other than transplantation. Group III PH affects patients with ongoing chronic lung injury, such as idiopathic pulmonary fibrosis (IPF
Autor:
Michael R. Blackburn, Harry Karmouty-Quintana, Yang Xia, Holger K. Eltzschig, Kelly A. Volcik, Ning Yuan Chen, Kemly Philip, Tingting Mills, Hong Liu, Jonathan Davies, Ngoc Bao Le, Fayong Luo, Jose G. Molina
Publikováno v:
The FASEB Journal. 30:874-883
Idiopathic pulmonary fibrosis is a devastating lung disease with limited treatment options. The signaling molecule adenosine is produced in response to injury and serves a protective role in early stages of injury and is detrimental during chronic st
Autor:
Jingjing Huang, Michael R. Blackburn, Xiang Lu, Yu Xiang, Leng Han, Kelly A. Volcik, Junsuk Ko, Tingting Weng, Ning Yuan Chen
Publikováno v:
Biochemical and biophysical research communications. 503(2)
Background Non-small cell lung cancer (NSCLC) is a life-threatening disease that has a poor prognosis and low survival rate. Cleavage factor Im 25 (CFIm25) is a RNA-binding protein that if down-regulated causes 3′UTR shortening and thus promotes th
Autor:
Ernestina Melicoff, Kelly A. Volcik, Luis J. Garcia-Morales, Michael R. Blackburn, R.R. Bunge, Tingting Weng, Brian A. Bruckner, Matthias Loebe, Jens M. Poth, Holger K. Eltzschig, Ning Yuan Chen, Fayong Luo, Harry Karmouty-Quintana, Christopher M. Evans
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 190:1402-1412
Idiopathic pulmonary fibrosis (IPF) is a deadly lung disease with few therapeutic options. Apoptosis of alveolar epithelial cells, followed by abnormal tissue repair characterized by hyperplastic epithelial cell formation, is a pathogenic process tha
Autor:
Richard S. Cooper, Angela Döring, Cisca Wijmenga, Jerome I. Rotter, Linda S. Adair, Tõnu Esko, Jennifer L. Bragg-Gresham, Danish Saleheen, Narisu Narisu, Xiaohui Li, Kathleen Stirrups, Ulf de Faire, Nicholas G. Martin, Dmitry Shungin, Peter Vollenweider, Yii-Der Ida Chen, Dharambir K. Sanghera, George Dedoussis, Toshiko Tanaka, Manjinder S. Sandhu, Anne U. Jackson, Nancy L. Pedersen, Maria Dimitriou, Shih-Yi Lin, David P. Strachan, Isleifur Olafsson, Ruth J. F. Loos, Kay-Tee Khaw, Antero Kesäniemi, Rainer Rauramaa, Wendy L. McArdle, Gonneke Willemsen, Dena G. Hernandez, May E. Montasser, Amy J. Swift, Colin A. McKenzie, Aaron Isaacs, Latonya F. Been, Leif Groop, Massimo Mangino, Martina Müller-Nurasyid, Karen L. Mohlke, Ci Song, Sailaja Vedantam, Anna-Liisa Hartikainen, Lori L. Bonnycastle, Ilja M. Nolte, Jaakko Kaprio, Anneli Pouta, Unnur Thorsteinsdottir, Paul Elliott, Muredach P. Reilly, Jean Ferrières, Daniel J. Rader, Elizabeth H. Young, Jaspal S. Kooner, Leena Moilanen, Markku Laakso, Albert Hofman, Kelly A. Volcik, Sekar Kathiresan, Tamara B. Harris, Eric Kim, Aimo Ruokonen, Andrea Ganna, Serena Sanna, John J.P. Kastelein, Martha L. Gravito, Ronald M. Krauss, Ken K. Ong, Paul M. Ridker, Kristian Hveem, Ayse Demirkan, Alena Stančáková, Pierre Meneton, Thomas Quertermous, John Danesh, Toby Johnson, Cornelia M. van Duijn, Samuli Ripatti, Christopher J. Groves, Jaakko Tuomilehto, Michael Boehnke, Jose M. Ordovas, Alan B. Feranil, Chao A. Hsiung, Wayne Huey-Herng Sheu, Igor Rudan, Christa Meisinger, Rebecca N. Nsubuga, Bruna Gigante, Inger Njølstad, Göran Hallmans, Aroon D. Hingorani, Jouko Saramies, Deepti Gurdasani, Fernando Rivadeneira, Andres Metspalu, Stephen E. Epstein, Gonçalo R. Abecasis, Braxton D. Mitchell, Devin Absher, Marcus E. Kleber, Sonia Shah, Pierre Fontanillas, Jeffrey R. O'Connell, Louise A. Donnelly, Jing Hua Zhao, Martin L. Buchkovich, Francis S. Collins, Gabrielle Müller, Matti Uusitupa, Evelin Mihailov, Nicholas J. Wareham, Andrew A. Hicks, Dorret I. Boomsma, Harry Campbell, Ellen M. Schmidt, Jaana Lindström, Mark I. McCarthy, Evita G. Van Den Herik, Kirsten Ohm Kyvik, Vilmundur Gudnason, Jackie F. Price, Joel N. Hirschhorn, Winfried März, Aravinda Chakravarti, Pontiano Kaleebu, James F. Wilson, Lindsay L. Waite, Leo-Pekka Lyytikäinen, Sebanti Sengupta, Mika Kivimäki, David Altshuler, Hilma Holm, Rona J. Strawbridge, Harald Grallert, Ramaiah Nagaraja, Laurence Tiret, G. Kees Hovingh, Meena Kumari, Nilesh J. Samani, Daniel F. Freitag, Nelson B. Freimer, Thomas Illig, Panos Deloukas, Bernhard O. Boehm, Nicholas W.J. Wainwright, Mark J. Daly, Mika Kähönen, Michel Burnier, Norman Klopp, L. Adrienne Cupples, Aarno Palotie, Markus Perola, Bamidele O. Tayo, Timo A. Lakka, Matthew Jones, Sarah H. Wild, Patricia B. Munroe, Antti Jula, François Mach, Peter J. Koudstaal, Pirjo Komulainen, Eric Boerwinkle, L. Joost van Pelt, Veikko Salomaa, Ann-Kristin Petersen, Ida Surakka, Andrew Wong, Caroline Hayward, Chi Gao, Cristen J. Willer, Stephen S. Rich, Yi Jen Hung, Peter P. Pramstaller, Diana Kuh, Ron Do, Dominique Arveiler, Mark O. Goodarzi, Ross M. Fraser, Ingrid B. Borecki, Steven C. Hunt, Weihua Zhang, Mary Susan Burnett, Patrik K. E. Magnusson, John C. Chambers, Benjamin M. Neale, Peter Schwarz, Jennifer L. Bolton, Murielle Bochud, Heleen M. den Hertog, Christian Gieger, Cristina Pomilla, Teresa Ferreira, Lars Wallentin, Richa Saxena, André G. Uitterlinden, Kaisa Silander, Ying Wu, Bruce M. Psaty, Jian'an Luan, Hsing-Yi Chang, Jin Chen, Daniel I. Chasman, Ulf Gyllensten, Kari Stefansson, Kauko Heikkilä, Tom Wilsgaard, Alan R. Shuldiner, Carlos Iribarren, Stavroula Kanoni, John Whitfield, Gershim Asiki, Marika Kaakinen, Georg Ehret, Elina Hyppönen, Claudia Langenberg, Gina M. Peloso, Cecilia M. Lindgren, Carlo Sidore, Gudmundur I. Eyjolfsson, Cameron D. Palmer, Jacques S. Beckmann, Hubert Scharnagl, Tanya M. Teslovich, Mary F. Feitosa, Terho Lehtimäki, Steve E. Humphries, Chris Power, Benjamin F. Voight, Stefania Bandinelli, Andrew D. Morris, Gudmar Thorleifsson, Tuomo Nieminen, Tim D. Spector, Paul W. Franks, Themistocles L. Assimes, Pascal Bovet, Luigi Ferrucci, Johannes Kettunen, Inês Barroso, Franklyn I. Bennett, Stefan Gustafsson, Paolo Brambilla, Theodore Papamarkou, Elena Tremoli, Janet Seeley, Alex S. F. Doney, Johanna Kuusisto, Giancarlo Cesana, Bruce H. R. Wolffenbuttel, Lars Lind, Stefan R. Bornstein, Åsa Johansson, Anders Hamsten, Marjo-Riitta Järvelin, Krista Fischer, Agneta Siegbahn, Samia Mora, Erik Ingelsson, Colin N. A. Palmer
Publikováno v:
Nature Genetics, 45(11), 1345-1352. Nature Publishing Group
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, no. 11, pp. 1345-1352 . https://doi.org/10.1038/ng.2795
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, pp. 1345-1352 . https://doi.org/10.1038/ng.2795
Nature genetics, 45(11), 1345-1352. Nature Publishing Group
Nature Genetics, 45(11), 1345-52. Nature Publishing Group
NATURE GENETICS
Nature genetics
Nature Genetics, 45(11), 1345-+. Nature Publishing Group
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A-K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A-L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y-J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K-T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S-Y, Lindström, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stančáková, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y-D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M-R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A, Munroe, P B, Njølstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H-H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, no. 11, pp. 1345-52 . https://doi.org/10.1038/ng.2795
Nature Genetics, vol. 45, no. 11, pp. 1345-1352
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L P, Magnusson, P K, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S Y, Lindström, J, Loos, R J, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N J, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N W, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A D, Hirschhorn, J N, Hofman, A, Hovingh, K G, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E, Sheu, W H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, no. 11, pp. 1345-1352 . https://doi.org/10.1038/ng.2795
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H Y, Demirkan, A, Den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkila, K, Hypponen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X H, Luan, J A, Lyytikainen, L P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Muller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W H, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Doring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimaki, T, Lin, S Y, Lindstrom, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Muller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stancakova, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrieres, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Jarvelin, M R, Jula, A, Kahonen, M, Kaprio, J, Kesaniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, Marz, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A D, Munroe, P B, Njolstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, pp. 1345-1352 . https://doi.org/10.1038/ng.2795
Nature genetics, 45(11), 1345-1352. Nature Publishing Group
Nature Genetics, 45(11), 1345-52. Nature Publishing Group
NATURE GENETICS
Nature genetics
Nature Genetics, 45(11), 1345-+. Nature Publishing Group
Do, R, Willer, C J, Schmidt, E M, Sengupta, S, Gao, C, Peloso, G M, Gustafsson, S, Kanoni, S, Ganna, A, Chen, J, Buchkovich, M L, Mora, S, Beckmann, J S, Bragg-Gresham, J L, Chang, H-Y, Demirkan, A, Den Hertog, H M, Donnelly, L A, Ehret, G B, Esko, T, Feitosa, M F, Ferreira, T, Fischer, K, Fontanillas, P, Fraser, R M, Freitag, D F, Gurdasani, D, Heikkilä, K, Hyppönen, E, Isaacs, A, Jackson, A U, Johansson, A, Johnson, T, Kaakinen, M, Kettunen, J, Kleber, M E, Li, X, Luan, J, Lyytikäinen, L-P, Magnusson, P K E, Mangino, M, Mihailov, E, Montasser, M E, Müller-Nurasyid, M, Nolte, I M, O'Connell, J R, Palmer, C D, Perola, M, Petersen, A-K, Sanna, S, Saxena, R, Service, S K, Shah, S, Shungin, D, Sidore, C, Song, C, Strawbridge, R J, Surakka, I, Tanaka, T, Teslovich, T M, Thorleifsson, G, Van den Herik, E G, Voight, B F, Volcik, K A, Waite, L L, Wong, A, Wu, Y, Zhang, W, Absher, D, Asiki, G, Barroso, I, Been, L F, Bolton, J L, Bonnycastle, L L, Brambilla, P, Burnett, M S, Cesana, G, Dimitriou, M, Doney, A S F, Döring, A, Elliott, P, Epstein, S E, Eyjolfsson, G I, Gigante, B, Goodarzi, M O, Grallert, H, Gravito, M L, Groves, C J, Hallmans, G, Hartikainen, A-L, Hayward, C, Hernandez, D, Hicks, A A, Holm, H, Hung, Y-J, Illig, T, Jones, M R, Kaleebu, P, Kastelein, J J P, Khaw, K-T, Kim, E, Klopp, N, Komulainen, P, Kumari, M, Langenberg, C, Lehtimäki, T, Lin, S-Y, Lindström, J, Loos, R J F, Mach, F, McArdle, W L, Meisinger, C, Mitchell, B D, Müller, G, Nagaraja, R, Narisu, N, Nieminen, T V M, Nsubuga, R N, Olafsson, I, Ong, K K, Palotie, A, Papamarkou, T, Pomilla, C, Pouta, A, Rader, D J, Reilly, M P, Ridker, P M, Rivadeneira, F, Rudan, I, Ruokonen, A, Samani, N, Scharnagl, H, Seeley, J, Silander, K, Stančáková, A, Stirrups, K, Swift, A J, Tiret, L, Uitterlinden, A G, van Pelt, L J, Vedantam, S, Wainwright, N, Wijmenga, C, Wild, S H, Willemsen, G, Wilsgaard, T, Wilson, J F, Young, E H, Zhao, J H, Adair, L S, Arveiler, D, Assimes, T L, Bandinelli, S, Bennett, F, Bochud, M, Boehm, B O, Boomsma, D I, Borecki, I B, Bornstein, S R, Bovet, P, Burnier, M, Campbell, H, Chakravarti, A, Chambers, J C, Chen, Y-D I, Collins, F S, Cooper, R S, Danesh, J, Dedoussis, G, de Faire, U, Feranil, A B, Ferrières, J, Ferrucci, L, Freimer, N B, Gieger, C, Groop, L C, Gudnason, V, Gyllensten, U, Hamsten, A, Harris, T B, Hingorani, A, Hirschhorn, J N, Hofman, A, Hovingh, G K, Hsiung, C A, Humphries, S E, Hunt, S C, Hveem, K, Iribarren, C, Järvelin, M-R, Jula, A, Kähönen, M, Kaprio, J, Kesäniemi, A, Kivimaki, M, Kooner, J S, Koudstaal, P J, Krauss, R M, Kuh, D, Kuusisto, J, Kyvik, K O, Laakso, M, Lakka, T A, Lind, L, Lindgren, C M, Martin, N G, März, W, McCarthy, M I, McKenzie, C A, Meneton, P, Metspalu, A, Moilanen, L, Morris, A, Munroe, P B, Njølstad, I, Pedersen, N L, Power, C, Pramstaller, P P, Price, J F, Psaty, B M, Quertermous, T, Rauramaa, R, Saleheen, D, Salomaa, V, Sanghera, D K, Saramies, J, Schwarz, P E H, Sheu, W H-H, Shuldiner, A R, Siegbahn, A, Spector, T D, Stefansson, K, Strachan, D P, Tayo, B O, Tremoli, E, Tuomilehto, J, Uusitupa, M, van Duijn, C M, Vollenweider, P, Wallentin, L, Wareham, N J, Whitfield, J B, Wolffenbuttel, B H R, Altshuler, D, Ordovas, J M, Boerwinkle, E, Palmer, C N A, Thorsteinsdottir, U, Chasman, D I, Rotter, J I, Franks, P W, Ripatti, S, Cupples, L A, Sandhu, M S, Rich, S S, Boehnke, M, Deloukas, P, Mohlke, K L, Ingelsson, E, Abecasis, G R, Daly, M J, Neale, B M & Kathiresan, S 2013, ' Common variants associated with plasma triglycerides and risk for coronary artery disease ', Nature Genetics, vol. 45, no. 11, pp. 1345-52 . https://doi.org/10.1038/ng.2795
Nature Genetics, vol. 45, no. 11, pp. 1345-1352
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this associatio