Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kelly A. Soderberg"'
Autor:
Sampa Santra, Georgia D Tomaras, Ranjit Warrier, Nathan I Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, S Munir Alam, Ruijun Zhang, Sarah L Cocklin, Xiaoying Shen, Ryan Duffy, Shi-Mao Xia, Robert J Schutte, Charles W Pemble Iv, S Moses Dennison, Hui Li, Andrew Chao, Kora Vidnovic, Abbey Evans, Katja Klein, Amit Kumar, James Robinson, Gary Landucci, Donald N Forthal, David C Montefiori, Jaranit Kaewkungwal, Sorachai Nitayaphan, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Merlin L Robb, Nelson L Michael, Jerome H Kim, Kelly A Soderberg, Elena E Giorgi, Lily Blair, Bette T Korber, Christiane Moog, Robin J Shattock, Norman L Letvin, Joern E Schmitz, M A Moody, Feng Gao, Guido Ferrari, George M Shaw, Barton F Haynes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005042 (2015)
HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protect
Externí odkaz:
https://doaj.org/article/ac4067627074462ba826fe0932273e87
Autor:
Susan Zolla-Pazner, Allan deCamp, Peter B Gilbert, Constance Williams, Nicole L Yates, William T Williams, Robert Howington, Youyi Fong, Daryl E Morris, Kelly A Soderberg, Carmela Irene, Charles Reichman, Abraham Pinter, Robert Parks, Punnee Pitisuttithum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Sorachai Nitayaphan, Charla Andrews, Robert J O'Connell, Zhi-yong Yang, Gary J Nabel, Jerome H Kim, Nelson L Michael, David C Montefiori, Hua-Xin Liao, Barton F Haynes, Georgia D Tomaras
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87572 (2014)
UnlabelledIn the RV144 HIV-1 vaccine efficacy trial, IgG antibody (Ab) binding levels to variable regions 1 and 2 (V1V2) of the HIV-1 envelope glycoprotein gp120 were an inverse correlate of risk of HIV-1 infection. To determine if V1V2-specific Abs
Externí odkaz:
https://doaj.org/article/908050f48a3743e69cae612588e66678
Autor:
S Gnanakaran, Tanmoy Bhattacharya, Marcus Daniels, Brandon F Keele, Peter T Hraber, Alan S Lapedes, Tongye Shen, Brian Gaschen, Mohan Krishnamoorthy, Hui Li, Julie M Decker, Jesus F Salazar-Gonzalez, Shuyi Wang, Chunlai Jiang, Feng Gao, Ronald Swanstrom, Jeffrey A Anderson, Li-Hua Ping, Myron S Cohen, Martin Markowitz, Paul A Goepfert, Michael S Saag, Joseph J Eron, Charles B Hicks, William A Blattner, Georgia D Tomaras, Mohammed Asmal, Norman L Letvin, Peter B Gilbert, Allan C Decamp, Craig A Magaret, William R Schief, Yih-En Andrew Ban, Ming Zhang, Kelly A Soderberg, Joseph G Sodroski, Barton F Haynes, George M Shaw, Beatrice H Hahn, Bette Korber
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002209 (2011)
Here we have identified HIV-1 B clade Envelope (Env) amino acid signatures from early in infection that may be favored at transmission, as well as patterns of recurrent mutation in chronic infection that may reflect common pathways of immune evasion.
Externí odkaz:
https://doaj.org/article/22d53c62f6de46ae98a1717e386d0e84
Autor:
Melanie Mackay, Jennifer L. Kirchherr, Marcella Sarzotti-Kelsoe, Leila K. Needham, Susan L. Stager, John Bainbridge, Guido Ferrari, Susan A. Fiscus, Takesha McMillion, Thomas N. Denny, Barton F. Haynes, Kristy O. Long, Wendy S. Stevens, Kelly A. Soderberg, Clive M. Gray, Niranjini Moodley, Wes Rountree, Pauline Mokgotho, Raul Louzao, Melissa Kerkau, Whitney Binz
Publikováno v:
Journal of Immunological Methods. 409:21-30
The Center for HIV/AIDS Vaccine Immunology (CHAVI) consortium was established to determine the host and virus factors associated with HIV transmission, infection and containment of virus replication, with the goal of advancing the development of an H
Autor:
Barton F. Haynes, Nisc Comparative Sequencing Program, John R. Mascola, Chaim A. Schramm, Krissey E. Lloyd, Robert Parks, Xiulian Du, Jiang Zhu, Lillian Tran, James C. Mullikin, Peter T. Hraber, Richard M. Scearce, Lawrence Shapiro, Shi-Mao Xia, Hua-Xin Liao, Peter D. Kwong, Fangping Cai, Zhenhai Zhang, Garnett Kelsoe, Sandrasegaram Gnanakaran, Feng Gao, Myron S. Cohen, Beatrice H. Hahn, M. Gordon Joyce, Anqi Zheng, Kevin Wiehe, Baoshan Zhang, Scott D. Boyd, Sanjay Srivatsan, Andrew Fire, Stephanie Moquin, Mark K. Louder, Guang Yang, S. Munir Alam, Gift Kamanga, Tongqing Zhou, Thomas B. Kepler, David C. Montefiori, Yue Chen, Bette T. Korber, Krishna M. Roskin, George M. Shaw, Rebecca M. Lynch, Kelly A. Soderberg, Sheri Chen
Publikováno v:
Nature
Current human immunodeficiency virus-1 (HIV-1) vaccines elicit strain-specific neutralizing antibodies. However, cross-reactive neutralizing antibodies arise in approximately 20% of HIV-1-infected individuals, and details of their generation could pr
Autor:
Kelly A. Soderberg, Damien Chaussabel, Marco F. Ramoni, Barton F. Haynes, Hsun-Hsien Chang, Jason A. Skinner, Jacques Banchereau, Norman L. Letvin
Publikováno v:
Journal of the American Medical Informatics Association. 19:1103-1109
Background HIV-1-infected individuals with higher viral set points progress to AIDS more rapidly than those with lower set points. Predicting viral set point early following infection can contribute to our understanding of early control of HIV-1 repl
Autor:
Richard Apps, Simon Mallal, Zabrina L. Brumme, Kelly A. Soderberg, Chanson J. Brumme, Ashley Moffett, Nelson L. Michael, Xue Zeng, James J. Goedert, Steven M. Wolinsky, Jonathan M. Carlson, Greg Q. Del Prete, Haoyan Chen, M. Anthony Moody, Yuko Yuki, Mina John, Susan Buchbinder, Jingyuan Fang, Gregory D. Kirk, Amy C. Weintrob, Steven G. Deeks, Florencia Pereyra, Xiaojiang Gao, Ronald J. Bosch, Thomas N. Denny, Jacques Fellay, Wilson Liao, George W. Nelson, Philip J. R. Goulder, Judy L. Stein, David Heckerman, Rasmi Thomas, Paul J. McLaren, Ying Qi, Jeffrey D. Lifson, Bruce D. Walker, Mary Carrington
Publikováno v:
Science, vol. 340, no. 6128, pp. 87-91
Science (New York, N.Y.), vol 340, iss 6128
Science (New York, N.Y.), vol 340, iss 6128
Thwarting HIV Multiple genome-wide association studies have revealed that human leukocyte antigen (HLA) genes of the major histocompatibility complex locus have the strongest impact on HIV. In particular, a single-nucleotide polymorphism 35 base pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9f631ad271b89170e5d18f3042deb5
https://ora.ox.ac.uk/objects/uuid:91e91a3a-bc20-4503-948e-488edc324579
https://ora.ox.ac.uk/objects/uuid:91e91a3a-bc20-4503-948e-488edc324579
Autor:
P R Shea, Isabela Pedroza-Pacheco, Persephone Borrow, Garnett Kelsoe, Ane Ogbe, M. A. Moody, Krissey E. Lloyd, Mark Connors, Kelly A. Soderberg, Myron S. Cohen, Laurent Verkoczy, Jinghe Huang, Andrew J. McMichael, Barton F. Haynes, Liao H-X., Nathan Vandergrift, R Parks, Feng Gao, C Chui, David C. Montefiori
Publikováno v:
Science Immunology. 1
Induction of broadly neutralizing antibodies (bnAbs) is a goal of HIV-1 vaccine development. bnAbs occur in some HIV-1–infected individuals and frequently have characteristics of autoantibodies. We have studied cohorts of HIV-1–infected individua
Autor:
David C. Montefiori, Yunda Huang, Georgia D. Tomaras, Nicole L. Yates, Hua-Xin Liao, Allan C. deCamp, Robert Paris, Supachai Rerks-Ngarm, Chitraporn Karnasuta, David T. Evans, Jerome H. Kim, Robert T. Bailer, Nelson L. Michael, Constance Williams, Youyi Fong, M. Juliana McElrath, Peter B. Gilbert, Erik Billings, Holly Janes, Viseth Ngauy, Mangala Rao, Sorachai Nitayaphan, Merlin L. Robb, Michael D. Alpert, George K. Lewis, Abraham Pinter, Guido Ferrari, Stephen C. De Rosa, Barton F. Haynes, Nicole Frahm, Richard A. Koup, Punnee Pitisuttithum, Xiaoying Shen, Kelly A. Soderberg, Charla Andrews, Ruengpueng Sutthent, Phillip W. Berman, Jaranit Kaewkungwal, S. Munir Alam, Susan Zolla-Pazner, Nicos Karasavvas, Mark de Souza, Anthony L. DeVico
Publikováno v:
New England Journal of Medicine. 366:1275-1286
In the RV144 trial, the estimated efficacy of a vaccine regimen against human immunodeficiency virus type 1 (HIV-1) was 31.2%. We performed a case-control analysis to identify antibody and cellular immune correlates of infection risk.In pilot studies
Autor:
Robin J. Shattock, Christiane Moog, Norman L. Letvin, Gary Landucci, Merlin L. Robb, Ryan Duffy, Georgia D. Tomaras, Elena E. Giorgi, Pinghuang Liu, Lily M. Blair, Guido Ferrari, Robert J. Schutte, Shi-Mao Xia, Supachai Rerks-Ngarm, M. A. Moody, Kelly A. Soderberg, S. Munir Alam, Nathan I. Nicely, Punnee Pitisuttithum, David C. Montefiori, Donald N. Forthal, Hui Li, Ruijun Zhang, Jerome H. Kim, Andrew Chao, Ranjit Warrier, Bette T. Korber, George M. Shaw, Amit Kumar, Nelson L. Michael, Sarah L. Cocklin, Kora Vidnovic, Hua-Xin Liao, Justin Pollara, James E. Robinson, Katja Klein, Jaranit Kaewkungwal, Charles W. Pemble, S. Moses Dennison, Joern E. Schmitz, Xiaoying Shen, Abbey Evans, Sorachai Nitayaphan, Feng Gao, Sampa Santra, Barton F. Haynes
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 11, Iss 8, p e1005042 (2015)
PLoS Pathogens, Vol 11, Iss 8, p e1005042 (2015)
HIV-1 mucosal transmission begins with virus or virus-infected cells moving through mucus across mucosal epithelium to infect CD4+ T cells. Although broadly neutralizing antibodies (bnAbs) are the type of HIV-1 antibodies that are most likely protect