Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kelly A. Newell"'
Autor:
Yi Liu, Yuyun Zhang, Xian Zheng, Tongyong Fang, Xia Yang, Xuan Luo, Anlei Guo, Kelly A. Newell, Xu-Feng Huang, Yinghua Yu
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Neuroinflammation plays an important role in the onset and progression of neurodegenerative diseases such as Alzheimer’s disease. Lipopolysaccharide (LPS, endotoxin) levels are higher in the brains of Alzheimer’s disease patie
Externí odkaz:
https://doaj.org/article/8ac32ec564254fd987ca5b803d523c60
Autor:
Yi Liu, Jie Huang, Xian Zheng, Xia Yang, Yan Ding, Tongyong Fang, Yuyun Zhang, Shuaishuai Wang, Xiaofei Zhang, Xuan Luo, Anlei Guo, Kelly A. Newell, Yinghua Yu, Xu-Feng Huang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Methylglyoxal (MG) accumulation has been observed in human cerebrospinal fluid and body tissues under hyperglycaemic conditions. Recent research has demonstrated that MG-induces neuronal cell apoptosis, which promotes the development of diab
Externí odkaz:
https://doaj.org/article/9cfd609f8aa54a7884e456f962e96767
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 171-173 (2014)
Science is often romanticised as a flawless system of knowledge building, where scientists work together to systematically find answers. In reality, this is not always the case. Dissemination of results are straightforward when the findings are posit
Externí odkaz:
https://doaj.org/article/df5d6474379d481ab067dc342a84ffac
Autor:
Samara J. Brown, Amelia M. Brown, Tertia D. Purves-Tyson, Xu-Feng Huang, Cynthia Shannon Weickert, Kelly A. Newell
Publikováno v:
Journal of Psychiatric Research. 160:204-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64334af28e8fb805ef16483ae976ede2
https://doi.org/10.1016/j.jpsychires.2023.02.017
https://doi.org/10.1016/j.jpsychires.2023.02.017
Autor:
Noor S. Jarbou, Kelly A. Newell
Publikováno v:
Archives of Women's Mental Health. 25:539-559
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44edaa6ed68c3f0aaba0d14dae3a1b2
https://doi.org/10.1007/s00737-021-01189-2
https://doi.org/10.1007/s00737-021-01189-2
Autor:
Gabrielle R. Phillips, Sarah E. Hancock, Andrew M. Jenner, Catriona McLean, Kelly A. Newell, Todd W. Mitchell
Publikováno v:
Nutrients; Volume 14; Issue 10; Pages: 2086
Huntington’s disease (HD) is a genetic, neurodegenerative illness that onsets in late adulthood as a series of progressive and terminal cognitive, motor, and psychiatric deficits. The disease is caused by a polyQ mutation in the Huntingtin gene (HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dbaa15037d2f42b295a8d94268e969
https://pubmed.ncbi.nlm.nih.gov/35631226
https://pubmed.ncbi.nlm.nih.gov/35631226
Autor:
Simon H. J. Brown, Fabian Kreilaus, Sarah E. Hancock, Andrew M. Jenner, Todd W. Mitchell, Kelly A. Newell, Gabrielle R. Phillips
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Huntington’s disease (HD) is an autosomal dominant neurodegenerative illness caused by a mutation in the huntingtin gene (HTT) and subsequent protein (mhtt), to which the brain shows a region-specific vulnerability. Disturbances in neural cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570ae4a4540f50358ee55faccaa02289
http://link.springer.com/article/10.1038/s41598-020-76973-8
http://link.springer.com/article/10.1038/s41598-020-76973-8
Autor:
Gabrielle R. Phillips, Jennifer T. Saville, Sarah E. Hancock, Simon H. J. Brown, Andrew M. Jenner, Catriona McLean, Maria Fuller, Kelly A. Newell, Todd W. Mitchell
Publikováno v:
Brain Communications. 4
Huntington’s disease is a devastating neurodegenerative disorder that onsets in late adulthood as progressive and terminal cognitive, psychiatric and motor deficits. The disease is genetic, triggered by a CAG repeat (polyQ) expansion mutation in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1bbc6293db967b2ee36d76b79464043
https://doi.org/10.1093/braincomms/fcab303
https://doi.org/10.1093/braincomms/fcab303
Autor:
Samara J. Brown, Amelia M. Brown, Tertia D. Purves-Tyson, Xu-Feng Huang, Cynthia Shannon Weickert, Kelly A. Newell
Publikováno v:
Journal of psychiatric research. 147
Evidence, largely obtained from peripheral studies, suggests that alterations in the kynurenine pathway contribute to the aetiology of depression and disorders involving psychosis. Stimulation of the kynurenine pathway leads to the formation of neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568cb10f163f0912ed095a358c776190
https://pubmed.ncbi.nlm.nih.gov/35063739
https://pubmed.ncbi.nlm.nih.gov/35063739
Autor:
Tasnim Rahman, Tertia Purves-Tyson, Amy E. Geddes, Xu-Feng Huang, Kelly A. Newell, Cynthia Shannon Weickert
Publikováno v:
Schizophrenia research. 240
Lower N-methyl-d-aspartate receptor (NMDAR) GluN1 subunit levels and heightened neuroinflammation are found in the cortex in schizophrenia. Since neuroinflammation can lead to changes in NMDAR function, it is possible that these observations are link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38c7c95168528ed9497e0cd996c3988
https://pubmed.ncbi.nlm.nih.gov/34952289
https://pubmed.ncbi.nlm.nih.gov/34952289