Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Kelly A. Martin"'
Autor:
Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the top five deadliest forms of cancer with very few treatment options. The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been su
Externí odkaz:
https://doaj.org/article/50a6f40489714f8794e255c10b83ab8d
Autor:
Jonathan Diaz, Bradford M. Kuhlman, Nicholas P. Edenhoffer, Angela C. Evans, Kelly A. Martin, Peter Guida, Adam Rusek, Anthony Atala, Matthew A. Coleman, Paul F. Wilson, Graça Almeida-Porada, Christopher D. Porada
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 10 (2023)
Introduction: Missions beyond low Earth orbit (LEO) will expose astronauts to ionizing radiation (IR) in the form of solar energetic particles (SEP) and galactic cosmic rays (GCR) including high atomic number and energy (HZE) nuclei. The gastrointest
Externí odkaz:
https://doaj.org/article/daa80d9fafef42c5a762ba9b7a91c8a6
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The overuse of antibiotics in clinical and livestock settings is accelerating the selection of multidrug resistant bacterial pathogens. Antibiotic resistant bacteria result in increased mortality and financial strain on the health care and l
Externí odkaz:
https://doaj.org/article/4eb68295c0204935a66ae6e7dccde002
Autor:
Aimy Sebastian, Nicholas R. Hum, Jillian L. McCool, Stephen P. Wilson, Deepa K. Murugesh, Kelly A. Martin, Naiomy Deliz Rios-Arce, Beheshta Amiri, Blaine A. Christiansen, Gabriela G. Loots
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people world-wide. Accumulating evidence attests to the important roles of the immune system in OA pathogenesis. Understanding the role of various immune cells in joint
Externí odkaz:
https://doaj.org/article/f300656bbb3c4474aac3fe6b2c690ffd
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81
Autor:
Angela C. Evans, Kelly A. Martin, Manoj Saxena, Sandra Bicher, Elizabeth Wheeler, Emilio J. Cordova, Christopher D. Porada, Graça Almeida-Porada, Takamitsu A. Kato, Paul F. Wilson, Matthew A. Coleman
Publikováno v:
Nanomaterials, Vol 12, Iss 20, p 3619 (2022)
Curcumin, a natural polyphenol derived from the spice turmeric (Curcuma longa), contains antioxidant, anti-inflammatory, and anti-cancer properties. However, curcumin bioavailability is inherently low due to poor water solubility and rapid metabolism
Externí odkaz:
https://doaj.org/article/e25d1db91076427fbfca6c4dc9823525
Autor:
Aimy Sebastian, Nicholas R. Hum, Kelly A. Martin, Sean F. Gilmore, Ivana Peran, Stephen W. Byers, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Cancers, Vol 12, Iss 5, p 1307 (2020)
Cancer-associated fibroblasts (CAFs) are a prominent stromal cell type in solid tumors and molecules secreted by CAFs play an important role in tumor progression and metastasis. CAFs coexist as heterogeneous populations with potentially different bio
Externí odkaz:
https://doaj.org/article/bdf6d5aa82e547d9b19a05ac56e3b351
Autor:
Nicholas R. Hum, Aimy Sebastian, Sean F. Gilmore, Wei He, Kelly A. Martin, Aubree Hinckley, Karen R. Dubbin, Monica L. Moya, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Cancers, Vol 12, Iss 3, p 690 (2020)
Current pre-clinical models of cancer fail to recapitulate the cancer cell behavior in primary tumors primarily because of the lack of a deeper understanding of the effects that the microenvironment has on cancer cell phenotype. Transcriptomic profil
Externí odkaz:
https://doaj.org/article/c4662626a5df46dd82f853540e0387f3
Autor:
Kelly A. Martin, Nicholas R. Hum, Aimy Sebastian, Wei He, Salma Siddiqui, Paramita M. Ghosh, Chong-xian Pan, Ralph de Vere White, Gabriela G. Loots
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 4983 (2019)
Bladder cancer is among the top ten most common cancers, with about ~380,000 new cases and ~150,000 deaths per year worldwide. Tumor relapse following chemotherapy treatment has long been a significant challenge towards completely curing cancer. We h
Externí odkaz:
https://doaj.org/article/cfed64506f70412e85377896473fc053
Autor:
Yunyun Yan, Tara E. Colenbrander Nelson, Lauren Twible, Kelly Whaley-Martin, Chad V. Jarolimek, Josh J. King, Simon C. Apte, James Arrey, Lesley A. Warren
Publikováno v:
Environmental Chemistry. 19:236-253
Environmental context Base Mine Lake (BML) is a demonstration pilot pit lake for long term oil sands tailings reclamation in Alberta, Canada. This study quantified BML water cap sulfur mass balance and speciation to help understand potential risks to