Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Kelly A. Hyndman"'
Autor:
Eman Y. Gohar, Carmen De Miguel, Ijeoma E. Obi, Elizabeth M. Daugherty, Kelly A. Hyndman, Bryan K. Becker, Chunhua Jin, Randee Sedaka, Jermaine G. Johnston, Pengyuan Liu, Joshua S. Speed, Tanecia Mitchell, Alison J. Kriegel, Jennifer S. Pollock, David M. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Premenopausal women are less likely to develop hypertension and salt‐related complications than are men, yet the impact of sex on mechanisms regulating Na+ homeostasis during dietary salt challenges is poorly defined. Here, we determined
Externí odkaz:
https://doaj.org/article/0cb3e71087914936a984fb5185dc2cdf
Autor:
Kelly A. Hyndman, Elena Isaeva, Oleg Palygin, Luciano D. Mendoza, Aylin R. Rodan, Alexander Staruschenko, Jennifer S. Pollock
Publikováno v:
Physiological Reports, Vol 9, Iss 20, Pp n/a-n/a (2021)
Abstract The nitric oxide (NO)‐generating enzyme, NO synthase‐1β (NOS1β), is essential for sodium (Na+) homeostasis and blood pressure control. We previously showed that collecting duct principal cell NOS1β is critical for inhibition of the ep
Externí odkaz:
https://doaj.org/article/9fc56951e59441bfb00452897d4b5cca
Autor:
Yasminye D. Pettway, Thomas H. Neder, Dao H. Ho, Brandon M. Fox, Mariah Burch, Jackson Colson, Xiaofen Liu, Cailin E. Kellum, Kelly A. Hyndman, Jennifer S. Pollock
Publikováno v:
Physiological Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Early life stress (ELS) is associated with cardiovascular disease (CVD) risk in adulthood, but the underlying vascular mechanisms are poorly understood. Increased hemoglobin and heme have recently been implicated to mediate endothelial dysfu
Externí odkaz:
https://doaj.org/article/5bc486dfdac249989f71609eb4382d1d
Autor:
Kelly A. Hyndman, Joshua S. Speed, Luciano D. Mendoza, John M. Allan, Jackson Colson, Randee Sedaka, Chunhua Jin, Hyun Jun Jung, Samir El-Dahr, David M. Pollock, Jennifer S. Pollock
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Histone deacetylase (HDAC) enzymes regulate transcription through epigenetic modification of chromatin structure, but their specific functions in the kidney remain elusive. We discovered that the human kidney expresses class I HDACs. Kidney medulla-s
Externí odkaz:
https://doaj.org/article/70882cc23e384efc94408f6a164a8b54
Autor:
Brandon M. Fox, Bryan K. Becker, Analia S. Loria, Kelly A. Hyndman, Chunhua Jin, Hannah Clark, Robin Johns, Masashi Yanagisawa, David M. Pollock, Jennifer S. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 4 (2018)
BackgroundAcute psychosocial stress provokes increases in circulating endothelin‐1 (ET‐1) levels in humans and animal models. However, key questions about the physiological function and cellular source of stress‐induced ET‐1 remain unanswered
Externí odkaz:
https://doaj.org/article/3d36ac3291ea4a22bbd6a74d03d640b1
Autor:
Kelly A. Hyndman, Elena V. Mironova, Jorge F. Giani, Courtney Dugas, Jessika Collins, Alicia A. McDonough, James D. Stockand, Jennifer S. Pollock
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundDuring high sodium intake, the renin‐angiotensin‐aldosterone system is downregulated and nitric oxide signaling is upregulated in order to remain in sodium balance. Recently, we showed that collecting duct nitric oxide synthase 1β is c
Externí odkaz:
https://doaj.org/article/90f47f2281bd4829b76b317c05a2cc01
Publikováno v:
Can J Physiol Pharmacol
The chemotherapeutic agent cisplatin accumulates in the kidney and induces acute kidney injury (AKI). Preclinical and clinical studies suggest that young female mice and women show greater recovery from cisplatin-AKI compared to young male mice and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01a678dd8b4346afc256f5e48a4c87f
https://doi.org/10.1139/cjpp-2022-0126
https://doi.org/10.1139/cjpp-2022-0126
Publikováno v:
Am J Physiol Renal Physiol
We reported that high salt (HS) intake stimulates renal collecting duct (CD) endothelin (ET) type B receptor (ETBR)/nitric oxide (NO) synthase 1β (NOS1β)-dependent NO production inhibiting the epithelial sodium channel (ENaC) promoting natriuresis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67093e45c1b3c0e9557a29c06522546
https://doi.org/10.1152/ajprenal.00323.2020
https://doi.org/10.1152/ajprenal.00323.2020
Autor:
Kelly A. Hyndman, David K. Crossman
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c8fac8e4b3cd193db79de32870d651
https://doi.org/10.1096/fasebj.2022.36.s1.0r845
https://doi.org/10.1096/fasebj.2022.36.s1.0r845
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bad82ec51b905f1231deec3bacb0a8a7
https://doi.org/10.1096/fasebj.2022.36.s1.r2511
https://doi.org/10.1096/fasebj.2022.36.s1.r2511