Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Kelly A. Avery‐Kiejda"'
Autor:
Christine L. Paul, Nicole M. Verrills, Stephen Ackland, Rodney Scott, Susan Goode, Ann Thomas, Sarah Lukeman, Sarah Nielsen, Judith Weidenhofer, James Lynam, Elizabeth A. Fradgley, Jarad Martin, Peter Greer, Stephen Smith, Cassandra Griffin, Kelly A. Avery-Kiejda, Nick Zdenkowski, Andrew Searles, Shanthi Ramanathan
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Translating research, achieving impact, and assessing impact are important aspirations for all research collaboratives but can prove challenging. The Hunter Cancer Research Alliance (HCRA) was funded from 2014 to 2021 to enhance c
Externí odkaz:
https://doaj.org/article/4771e64c6f024016b0a738d8a8744d75
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Melanoma is the deadliest type of skin cancer and despite improvements in treatment outcomes, melanoma claimed 57,043 lives in 2020. In most malignancies, p53 mutation rates are above 50% and provide prognostic indications. Howeve
Externí odkaz:
https://doaj.org/article/45900f5327894d22853e1f56999f5208
Autor:
Luiza Steffens Reinhardt, Kira Groen, Xiajie Zhang, Brianna C. Morten, Anna Wawruszak, Kelly A. Avery-Kiejda
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-16 (2023)
Abstract In breast cancer, dysregulated TP53 expression signatures are a better predictor of chemotherapy response and survival outcomes than TP53 mutations. Our previous studies have shown that high levels of Δ40p53 are associated with worse diseas
Externí odkaz:
https://doaj.org/article/4c76e7e4a6244b3fb6e59a27df555b9e
Autor:
Luiza Steffens Reinhardt, Xiajie Zhang, Kira Groen, Brianna C. Morten, Geoffry N. De Iuliis, Antony W. Braithwaite, Jean-Christophe Bourdon, Kelly A. Avery-Kiejda
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-18 (2022)
Abstract Our previous studies have shown that p53 isoform expression is altered in breast cancer and related to prognosis. In particular, a high ∆40p53:p53α ratio is associated with worse disease-free survival. In this manuscript, the influence of
Externí odkaz:
https://doaj.org/article/9cb81a5c712a40c4a75be9cdbbd0bfac
Autor:
Xiajie Zhang, Kira Groen, Brianna C. Morten, Luiza Steffens Reinhardt, Hamish G. Campbell, Antony W. Braithwaite, Jean‐Christophe Bourdon, Kelly A. Avery‐Kiejda
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 447-465 (2022)
Breast cancer is the most diagnosed malignancy in women, with over half a million women dying from this disease each year. In our previous studies, ∆40p53, an N‐terminally truncated p53 isoform, was found to be upregulated in breast cancers, and
Externí odkaz:
https://doaj.org/article/d096e9855e9f4682af97e433816271a0
Copy number variation in triple negative breast cancer samples associated with lymph node metastasis
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 8, Pp 743-753 (2021)
Triple negative breast cancer (TNBC) is a highly metastatic and aggressive subtype of breast cancer and cases presenting with lymph node involvement have worse outcomes. This study aimed to determine the regions of copy number variation (CNV) associa
Externí odkaz:
https://doaj.org/article/5c98fe8df266461dbfefd74d0dfbf7f1
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triple negative breast cancer (TNBC) is a highly aggressive subtype with a high rate of metastasis, early distant recurrence and resistance to therapy leading to worse survival than other breast cancer subtypes. There are no well-established biomarke
Externí odkaz:
https://doaj.org/article/799cc957d2e6442b8a47aa15e24fc428
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Secondary lymphedema is characterized by lymphatic fluid retention and subsequent tissue swelling in one or both limbs that can lead to decreased quality of life. It often arises after loss, obstruction, or blockage of lymphatic vessels due to multif
Externí odkaz:
https://doaj.org/article/21da2aa09f314711a6349dcb910cde60
Publikováno v:
Genomics Data, Vol 14, Iss C, Pp 1-4 (2017)
Triple negative breast cancer (TNBC) is a particularly important breast cancer subtype with an aggressive clinical phenotype that is associated with a higher likelihood of metastasis. This subtype is characterized by an absence of the estrogen (ER) a
Externí odkaz:
https://doaj.org/article/61ec64b74ebc44f19e13a0cd264c81b6
Autor:
Khairunnisa’ Md Yusof, Kelly A. Avery-Kiejda, Shafinah Ahmad Suhaimi, Najwa Ahmad Zamri, Muhammad Ehsan Fitri Rusli, Rozi Mahmud, Suraini Mohd Saini, Shahad Abdul Wahhab Ibraheem, Maha Abdullah, Rozita Rosli
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1303 (2021)
Breast cancer has been reported to have the highest survival rate among various cancers. However, breast cancer survivors face several challenges following breast cancer treatment including breast cancer-related lymphedema (BCRL), sexual dysfunction,
Externí odkaz:
https://doaj.org/article/64f11f27795d490cbee3b208f24ea528