Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kelly A Combs"'
Autor:
Jennifer M Hahn, Kelly A Combs, Christopher M Lloyd, Kevin L McFarland, Steven T Boyce, Dorothy M Supp
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213325 (2019)
Engineered skin substitutes (ESS), prepared using primary human fibroblasts and keratinocytes with a biopolymer scaffold, were shown to provide stable closure of excised burns, but relatively little is known about innervation of ESS after grafting. T
Externí odkaz:
https://doaj.org/article/38c54458966343c997cba9612767d5e3
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101172- (2022)
Summary: Four types of primary cells—dermal fibroblasts, dermal microvascular endothelial cells, epidermal keratinocytes, and epidermal melanocytes—can be isolated simultaneously from a single human skin sample, without the use of xenogeneic muri
Externí odkaz:
https://doaj.org/article/9451912b5aa14ec2b82e27f13f0a5425
Autor:
Christopher M. Lloyd, Kelly A. Combs, Dorothy M. Supp, Viki B. Swope, Steven T. Boyce, Zalfa A. Abdel-Malek, Jennifer M. Hahn
Publikováno v:
Journal of Burn Care & Research. 41:751-760
Engineered skin substitutes (ESS) containing autologous fibroblasts and keratinocytes provide stable wound closure in patients with large, full-thickness burns, but are limited by hypopigmentation due to absence of added melanocytes. DNA damage cause
Publikováno v:
Plastic and Reconstructive Surgery - Global Open. 10:e4680
Keloids are disfiguring, scar-like lesions that are challenging to treat, with low response rates to current interventions and frequent recurrence. It has been widely reported that keloids are characterized by myofibroblasts, specialized contractile
Autor:
Heather M. Powell, Raymond E. Boissy, Steven T. Boyce, Kelly A. Combs, Ann Schwentker, Anne W. Lucky, Kevin L. McFarland, Dorothy M. Supp, Jennifer M. Hahn
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 28 (2019)
Cell Transplantation, Vol 28 (2019)
The blistering disease recessive dystrophic epidermolysis bullosa (RDEB) is caused by mutations in the gene encoding collagen VII (COL7), which forms anchoring fibrils that attach the epidermis to the dermis. Cutaneous gene therapy to restore COL7 ex
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyREFERENCES. 29(5)
Keloids are fibroproliferative lesions resulting from an abnormal wound healing process due to pathological mechanisms that remain incompletely understood. Keloids tend to occur more frequently in anterior versus posterior body regions (e.g., ears, f
Publikováno v:
Journal of Burn Care & Research. 43:S145-S145
Introduction Keloids are disfiguring, fibroproliferative lesions that can result from an abnormal wound healing process. Keloids are characterized by excessive and abnormal deposition of extracellular matrix and unrestrained expansion beyond the orig
Publikováno v:
Journal of Burn Care & Research. 42:S93-S94
Introduction Keloids are disfiguring lesions that result from an abnormal wound healing process. Despite the availability of numerous therapeutic options, keloids remain challenging to treat and often recur after therapy. α-Mangostin, a natural xant
Autor:
Viki B. Swope, Jennifer M. Hahn, Steven T. Boyce, Christopher M. Lloyd, Kelly A. Combs, Zalfa A. Abdel-Malek, Dorothy M. Supp
Publikováno v:
Journal of Burn Care & Research. 41:S78-S79
Introduction Engineered skin substitutes (ESS) were developed to meet the need for prompt wound closure in patients with large full thickness burns. ESS containing autologous fibroblasts and keratinocytes were shown to provide stable wound closure in
Publikováno v:
Biochemistry. 57(19)
An important but poorly characterized contribution to the thermodynamics of protein-DNA interactions is the loss of entropy that occurs from restricting the conformational freedom of amino acid side chains. The effect of restricting the flexibility o