Tryptophan catabolites and depression in the general population: results from the Gutenberg Health Study

Autor: Matthias Michal, Andreas Schulz, Philipp S. Wild, Thomas Koeck, Thomas Münzel, Alexander K. Schuster, Konstantin Strauch, Karl Lackner, Sigurd D. Süssmuth, Heiko G. Niessen, Andreas Borta, Kelly A. Allers, Daniela Zahn, Manfred E. Beutel

Publikováno v: BMC Psychiatry, Vol 23, Iss 1, Pp 1-9 (2023)

Abstract Previous studies reported significantly altered tryptophan catabolite concentrations in major depression. Thus, tryptophan catabolites were considered as potential biomarkers of depression and their modulators as potential targets for psycho

Externí odkaz: https://doaj.org/article/40643a4100984f27990ac5b3287ed2f3

Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy

Autor: Karen M. Ryan, Kelly A. Allers, Andrew Harkin, Declan M. McLoughlin

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 4, Iss , Pp 100063- (2020)

A growing body of research has indicated a role for B vitamins in depression, with some previous studies suggesting that B vitamin status in patients with depression can impact on antidepressant response. Here we aimed to investigate B vitamin plasma

Externí odkaz: https://doaj.org/article/f5b1eaceeb474ef3a2990429f8b80a68

Peripheral metabolites of the kynurenine pathway are decreased in serious mental illness and show phase-specific differences in bipolar disorder patients

Autor: Murielle Brum, Matthias Nieberler, Christopher Kehrwald, Katrin Knopf, Nathalie Brunkhorst-Kanaan, Semra Etyemez, Kelly A Allers, Robert A. Bittner, David A. Slattery, Rhiannon V. McNeill, Andreas Reif, Sarah Kittel-Schneider

Background Previous studies have linked disturbances in the kynurenine pathway, responsible for the main catabolism of tryptophan and a key regulator of the immune system, to mental disorders such as major depressive disorder (MDD), bipolar disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d5301f3fa4192a4c65f0e3dd6f7c8d9
https://doi.org/10.21203/rs.3.rs-1855542/v1

The association between plasma tryptophan catabolites and depression

Autor: Yuri Milaneschi, Brenda W.J.H. Penninx, Robert A. Schoevers, Heiko G. Niessen, Kelly A. Allers, Erik J. Giltay, Sigurd D. Süssmuth, Aartjan T.F. Beekman, Sascha Keller

Publikováno v: Brain, Behavior, and Immunity, 97, 167-175. Academic Press Inc.
Milaneschi, Y, Allers, K A, Beekman, A T F, Giltay, E J, Keller, S, Schoevers, R A, Süssmuth, S D, Niessen, H G & Penninx, B W J H 2021, ' The association between plasma tryptophan catabolites and depression: The role of symptom profiles and inflammation ', Brain, Behavior, and Immunity, vol. 97, pp. 167-175 . https://doi.org/10.1016/j.bbi.2021.07.007
Brain, Behavior, and Immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE
Brain behavior and immunity, 97, 167-175. ACADEMIC PRESS INC ELSEVIER SCIENCE

Background: Tryptophan catabolites ("TRYCATs") produced by the kynurenine pathway (KP) may play a role in depression pathophysiology. Studies comparing TRYCATs levels in depressed subjects and controls provided mixed findings. We examined the associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b038c19f3037c1af5021a89cf3c7e702
https://doi.org/10.1016/j.bbi.2021.07.007

Editorial: The Jilted Brain: Neglected Structures and Functions

Autor: Natalie M. Zahr, Kelly A. Allers, Regina A. Mangieri

Publikováno v: Frontiers in Systems Neuroscience, Vol 15 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e919fd7e985e8dc75cf7138e76122fbe
https://www.frontiersin.org/articles/10.3389/fnsys.2021.716242/full