Abstracts from the 3rd International Severe Asthma Forum (ISAF)

Autor: M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw, Ana R. Sousa, Louise J. Fleming, Graham Roberts, Ioannis Pandis, Aruna T. Bansal, Julie Corfield, Scott Wagers, Ratko Djukanovic, Kian Fan Chung, Peter J. Sterk, Jorgen Vestbo, Stephen J. Fowler, S. J. Tebbutt, A. Singh, C. P. Shannon, Y. W. Kim, C. X. Yang, G. M. Gauvreau, J. M. Fitzgerald, L. P. Boulet, P. M. O’Byrne, N. Begley, A. Loudon, D. W. Ray, Selene Baos, Lucía Cremades, David Calzada, Carlos Lahoz, Blanca Cárdaba, Kewal Asosingh, Chris Lauruschkat, Kimberly Queisser, Nicholas Wanner, Kelly Weiss, Weiling Xu, Serpil Erzurum, Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Carolea Logun, Sara Alsaaty, Rosemarie Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron Armando, Edward Dennis, Stewart Levine, James Shelhamer, Kilyong Choi, Snezhina Lazova, Penka Perenovska, Dimitrinka Miteva, Stamatios Priftis, Guergana Petrova, Vassil Yablanski, Evgeni Vlaev, Hristina Rafailova, Takashi Kumae, L. J. Holmes, J. Yorke, D. M. Ryan, Sasawan Chinratanapisit, Khlongtip Matchimmadamrong, Jitladda Deerojanawong, Wissaroot Karoonboonyanan, Paskorn Sritipsukho, Vania Youroukova, Denitsa Dimitrova, Yanina Slavova, Spaska Lesichkova, Iren Tzocheva, Snezhana Parina, Svetla Angelova, Neli Korsun, Mihai Craiu, Iustina Violeta Stan, Matea Deliu, Tolga Yavuz, Matthew Sperrin, Umit M. Sahiner, Danielle Belgrave, Cansin Sackesen Sackesen, Ömer Kalayci, Petar Velikov, Tsvetelina Velikova, Ekaterina Ivanova-Todorova, Kalina Tumangelova-Yuzeir, Dobroslav Kyurkchiev, Spyridon Megremis, Bede Constantinides, Alexandros Georgios Sotiropoulos, Paraskevi Xepapadaki, David Robertson, Nikolaos Papadopoulos, Maxim Wilkinson, Craig Portsmouth, David Ray, Royston Goodacre, Anna Valerieva, Irina Bobolea, Daiana Guillén Vera, Gabriel Gonzalez-Salazar, Carlos Melero Moreno, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, R. Wang, I. Satia, R. Niven, J. A. Smith, T. Southworth, J. Plumb, V. Gupta, J. Pearson, I. Ramis, M. D. Lehner, M. Miralpeix, D. Singh, Imran Satia, Mark Woodhead, Paul O’Byrne, Jaclyn Ann Smith, Cecilia Forss, Peter Cook, Sheila Brown, Freya Svedberg, Katherine Stephenson, Margherita Bertuzzi, Elaine Bignell, Malin Enerbäck, Danen Cunoosamy, Andrew Macdonald, Caini Liu, Liang Zhu, Kiochi Fukuda, Cunjin Zhang, Suidong Ouyang, Xing Chen, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li, Marie-Chantal Larose, Anne-Sophie Archambault, Véronique Provost, Jamila Chakir, Michel Laviolette, Nicolas Flamand, Nicola Logan, Dominik Ruckerl, Judith E. Allen, Tara E. Sutherland, E. Hamelmann, C. Vogelberg, S. Goldstein, G. E. Azzi, M. Engel, R. Sigmund, S. J. Szefler, Raquel Mesquita, Luis Coentrão, Rui Veiga, José-Artur Paiva, Roberto Roncon-Albuquerque, Wendy Vargas Porras, Ana González Moreno, Jesus Macías Iglesias, Gustavo Córdova Ramos, Yesenia Peña Acevedo, Miguel Angel Tejedor Alonso, Maria Del Mar Moro Moro, Irena Krcmova, Jakub Novosad, Nicola Alexander Hanania, Marc Massanari, Heike Hecker, Eric Kassel, Craig Laforce, Kathy Rickard, Sanne Snelder, Gert-Jan Braunstahl, T. L. Jones, D. Neville, E. R. Heiden, E. Lanning, T. Brown, H. Rupani, K. S. Babu, A. J. Chauhan, M. Y. Eldegeir, A. A. Chapman, M. Ferwana, M. Caldron

Publikováno v: Clinical and Translational Allergy, Vol 7, Iss S2, Pp 1-17 (2017)

Externí odkaz: https://doaj.org/article/8aa220adbd1b41528cac7a760f22478f

M1 Positive Allosteric Modulators Enhance Domains of Cognitive Function by Activation of ssT-expressing Interneurons in the Prefrontal Cortex

Autor: Jerri Rook, Zixiu Xiang, Jonathan Dickerson, Shalini Dogra, Kendall Jensen, Insung Kim, Megan Ohler, Kelly Weiss, P. Jeffrey Conn

Publikováno v: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Behavioral.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c500f4aeea526375bc0949b7c50816d
https://doi.org/10.1124/jpet.122.253010

Barrier Housing and Gender Effects on Allergic Airway Disease in a Murine House Dust Mite Model

Autor: Kimberly Queisser, Kewal Asosingh, Serpil C. Erzurum, Timothy Myshrall, Matthew Frimel, Nicholas Wanner, Naseer Sangwan, Kelly Weiss, Tina Nunn

Publikováno v: ImmunoHorizons. 5:33-47

Allergic airway disease models use laboratory mice housed in highly controlled and hygienic environments, which provide a barrier between the mice and a predetermined list of specific pathogens excluded from the facility. In this study, we hypothesiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f9a1b15fa5d8058a85e39390c72142
https://doi.org/10.4049/immunohorizons.2000096

Persistent challenges in the development of an mGlu7 PAM in vivo tool compound: The discovery of VU6046980

Autor: Jacob J. Kalbfleisch, Alice L. Rodriguez, Xia Lei, Kelly Weiss, Annie L. Blobaum, Olivier Boutaud, Colleen M. Niswender, Craig W. Lindsley

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 80:129106

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c6683e4aabcb0b203e22042dfd21f38
https://doi.org/10.1016/j.bmcl.2022.129106

Arginine metabolic control of airway inflammation

Autor: Kelly Weiss, Serpil C. Erzurum, Carole Bennett, Kewal Asosingh, Nicholas Wanner, Weiling Xu, Mario Alemagno, Sean P. Kessler, Matthew Frimel, Deborah A. Meyers, Chris D Lauruschkat

Publikováno v: JCI Insight. 5

Inducible nitric oxide synthase (iNOS) and arginase-2 (ARG2) share a common substrate, arginine. Higher expression of iNOS and exhaled NO are linked to airway inflammation in patients. iNOS deletion in animal models suggests that eosinophilic inflamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807fe59bc59301d71dddc39c7898e88a
https://doi.org/10.1172/jci.insight.127801