Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kelly, Kries"'
Autor:
Andrea K. Corbet, Emmanuel Bikorimana, Raya I. Boyd, Doha Shokry, Kelly Kries, Ayush Gupta, Anneliese Paton, Zhengyang Sun, Zeeshan Fazal, Sarah J. Freemantle, Erik R. Nelson, Michael J. Spinella, Ratnakar Singh
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101676- (2023)
G0/G1 switch gene 2 (G0S2) is known to inhibit lipolysis by inhibiting adipose triglyceride lipase (ATGL). In this report, we dissect the role of G0S2 in ER+ versus ER- breast cancer. Overexpression of G0S2 in ER- cells increased cell proliferation,
Externí odkaz:
https://doaj.org/article/cbcbc9b7c9dc4ba880141b3cdbbac673
Autor:
Rie Asada Kitamura, Kristina G. Maxwell, Wenjuan Ye, Kelly Kries, Cris M. Brown, Punn Augsornworawat, Yoel Hirsch, Martin M. Johansson, Tzvi Weiden, Joseph Ekstein, Joshua Cohen, Justin Klee, Kent Leslie, Anton Simeonov, Mark J. Henderson, Jeffrey R. Millman, Fumihiko Urano
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Wolfram syndrome is a rare genetic disorder largely caused by pathogenic variants in the WFS1 gene and manifested by diabetes mellitus, optic nerve atrophy, and progressive neurodegeneration. Recent genetic and clinical findings have revealed Wolfram
Externí odkaz:
https://doaj.org/article/24a5fd515d1d461683a1b821a7ee0008
Autor:
Damien Abreu, Stephen I. Stone, Toni S. Pearson, Robert C. Bucelli, Ashley N. Simpson, Stacy Hurst, Cris M. Brown, Kelly Kries, Chinyere Onwumere, Hongjie Gu, James Hoekel, Lawrence Tychsen, Gregory P. Van Stavern, Neil H. White, Bess A. Marshall, Tamara Hershey, Fumihiko Urano
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
BACKGROUND Wolfram syndrome is a rare ER disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, and progressive neurodegeneration. Although there is no treatment for Wolfram syndrome, preclinical studies in cell and roden
Externí odkaz:
https://doaj.org/article/cc59812ac3294482ac751139a8922e28
Autor:
David W. Piston, Fumihiko Urano, John M P Revilla, Kelly Kries, Rie Asada, Damien Abreu, Zeno Lavagnino
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Wolfram Syndrome 1 (WFS1) protein is an endoplasmic reticulum (ER) factor whose deficiency results in juvenile-onset diabetes secondary to cellular dysfunction and apoptosis. The mechanisms guiding β-cell outcomes secondary to WFS1 function, however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f300202f97b53aa1b2660559e6cd0264
http://europepmc.org/articles/PMC7286786
http://europepmc.org/articles/PMC7286786
Autor:
Ashley N Simpson, Damien Abreu, Toni S. Pearson, Hongjie Gu, Tamara Hershey, Neil H. White, Gregory P. Van Stavern, James Hoekel, Stacy Hurst, Robert C. Bucelli, Chinyere Onwumere, Cris M. Brown, Bess A. Marshall, Stephen I. Stone, Fumihiko Urano, Kelly Kries, Lawrence Tychsen
Publikováno v:
JCI Insight.
BACKGROUNDWolfram syndrome is a rare ER disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, and progressive neurodegeneration. Although there is no treatment for Wolfram syndrome, preclinical studies in cell and rodent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5edd7c99fdbfd313a376062271daaae6
https://doi.org/10.1172/jci.insight.145188
https://doi.org/10.1172/jci.insight.145188
Autor:
Rolf Graf, Jana Mahadevan, Rie Asada, Bess A. Marshall, Stephen I. Stone, Kelly Kries, Damien Abreu, Fumihiko Urano, Tamara Hershey
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Endoplasmic reticulum (ER) stress in beta cells is an important pathogenic component of both type 1 and type 2 diabetes mellitus, as well as genetic forms of diabetes, especially Wolfram syndrome. However, there are currently no convenient ways to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e49f339e9458fdfe9904119fec4b37
http://link.springer.com/article/10.1038/s41598-019-41604-4
http://link.springer.com/article/10.1038/s41598-019-41604-4
Autor:
Fumihiko Urano, Rie Asada Kitamura, Kristina Maxwell, Wenjuan Ye, Kelly Kries, Cris Brown, Punn Augsornworawat, Martin Johansson, Joshua Cohen, Justin Klee, Kent Leslie, Anton Simeonov, Joel Hirsch, Tzvi Weiden, Mark Henderson, Jeffrey Millman, Josef Ekstein
Publikováno v:
Genetics in Medicine. 24:S167
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6caadc9c6dcff758065df0a0ada37306
https://doi.org/10.1016/j.gim.2022.01.299
https://doi.org/10.1016/j.gim.2022.01.299
Autor:
Damien, Abreu, Stephen I, Stone, Toni S, Pearson, Robert C, Bucelli, Ashley N, Simpson, Stacy, Hurst, Cris M, Brown, Kelly, Kries, Chinyere, Onwumere, Hongjie, Gu, James, Hoekel, Lawrence, Tychsen, Gregory P, Van Stavern, Neil H, White, Bess A, Marshall, Tamara, Hershey, Fumihiko, Urano
Publikováno v:
JCI Insight
BACKGROUND Wolfram syndrome is a rare ER disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, and progressive neurodegeneration. Although there is no treatment for Wolfram syndrome, preclinical studies in cell and roden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5250eadabd7d799a0ccdbfeff589a267
https://pubmed.ncbi.nlm.nih.gov/34185708
https://pubmed.ncbi.nlm.nih.gov/34185708
Autor:
Neil H. White, Toni S. Pearson, Stacy Hurst, Hongjie Gu, Tamara Hershey, Ashley N Simpson, Lawrence Tychsen, Cris M. Brown, Kelly Kries, James Hoekel, Damien Abreu, Bess A. Marshall, Stephen I. Stone, Fumihiko Urano, Robert C. Bucelli, Gregory P. Van Stavern
BackgroundWolfram syndrome is a rare endoplasmic reticulum disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, and progressive neurodegeneration. Although there is currently no treatment to delay, halt, or reverse the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb70672123fe31e0eed6b81fc5615a0f
https://doi.org/10.1101/2020.10.07.20208694
https://doi.org/10.1101/2020.10.07.20208694
Autor:
Mareike C. Janiak, Joseph D. Orkin, Gwen Duytschaever, Amanda D. Melin, Kelly Kries, Daniel M.A. Pessoa, Marília A. S. Barros
Publikováno v:
Molecular Ecology. 27:3627-3640
Bats are a diverse radiation of mammals of enduring interest for understanding the evolution of sensory specialization. Colour vision variation among species has previously been linked to roosting preferences and echolocation form in the suborder Yin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86a1382a591cb6d1f94b8851fb20d7d
https://doi.org/10.1111/mec.14818
https://doi.org/10.1111/mec.14818