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Autor:
Todd C. Metzger, Imran S. Khan, James M. Gardner, Maria L. Mouchess, Kellsey P. Johannes, Anna K. Krawisz, Katarzyna M. Skrzypczynska, Mark S. Anderson
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 166-179 (2013)
Thymic epithelial cells in the medulla (mTECs) play a critical role in enforcing central tolerance through expression and presentation of tissue-specific antigens (TSAs) and deletion of autoreactive thymocytes. TSA expression requires autoimmune regu
Externí odkaz:
https://doaj.org/article/0bcb43b5b7ce4ed0b3aeaddfe559da99