1114 Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models

Autor: Elizabeth Gray, Priyanka Gupta, Weiping Zeng, Shyra Gardai, Kaleb Smith, Katie Snead, Adam Hill, Kellie Spahr, Alyson J Smith, Elizabeth Cummins, David Gruber, Michelle L Ulrich, Mallory Long, Katelyn Hinricher, Aditi Langalia, Patrick Burke, Peter Senter

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/3d10db68c1aa4ab699f45680ebe496a8

SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models

Autor: Elizabeth Gray, Kelly Hensley, Sean Allred, Robert Thurman, Katie Snead, Michelle Ulrich, Dannah Miller, Serena Wo, Angela Epp, Disha Sahetya, Julie Hahn, Chris Frantz, Natalya Nazarenko, Kellie Spahr, Patrick Younan, Li-Ya Huang, Kristen Gahnberg, Piper M Treuting, Esther S Trueblood, John J Gosink, Evgenia Jane Haass, Mary Padilla, Alyson J Smith, Jason P Schrum, Shyra J Gardai

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)

Background SGN-B7H4V is a novel investigational vedotin antibody–drug conjugate (ADC) comprising a B7-H4-directed human monoclonal antibody conjugated to the cytotoxic payload monomethyl auristatin E (MMAE) via a protease-cleavable maleimidocaproyl

Externí odkaz: https://doaj.org/article/f885976e5e104e04a8016c6dbb713fb4

Applying the Creative Process to Library Branding

Autor: Kellie Sparks

Publikováno v: Marketing Libraries Journal, Vol 1, Iss 1, Pp 30-39 (2017)

How does one cultivate creative inspiration on demand and sustain it over the life of a project? As a library marketing professional, it can be challenging to sustain creativity when crafting ideas to establish or re-envision a library brand. This a

Externí odkaz: https://doaj.org/article/10418b377f6344c79c88755cd7bd1183

Enteral nutrition as stress ulcer prophylaxis in critically ill patients: A randomized controlled exploratory study.

Autor: El-Kersh K; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States. Electronic address: karim.elkersh@louisville.edu., Jalil B; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., McClave SA; University of Louisville School of Medicine, Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville, KY, United States., Cavallazzi R; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., Guardiola J; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., Guilkey K; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., Persaud AK; University of Louisville School of Medicine, Department of Internal Medicine, Division of Infectious Disease, University of Louisville, KY, United States., Furmanek SP; University of Louisville School of Medicine, Department of Internal Medicine, Division of Infectious Disease, University of Louisville, KY, United States., Guinn BE; University of Louisville School of Medicine, Department of Internal Medicine, Division of Infectious Disease, University of Louisville, KY, United States., Wiemken TL; University of Louisville School of Medicine, Department of Internal Medicine, Division of Infectious Disease, University of Louisville, KY, United States., Alhariri BC; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., Kellie SP; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States., Saad M; University of Louisville School of Medicine, Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Louisville, KY, United States.

Publikováno v: Journal of critical care [J Crit Care] 2018 Feb; Vol. 43, pp. 108-113. Date of Electronic Publication: 2017 Aug 26.