Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kellie S Reynolds"'
Autor:
Xinyuan Zhang, Yuching Yang, Manuela Grimstein, Guansheng Liu, Eliford Kitabi, Jianghong Fan, Ying‐Hong Wang, Justin Earp, James L. Weaver, Hao Zhu, Jiang Liu, Kellie S. Reynolds, Shiew‐Mei Huang, Yaning Wang
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 973-982 (2021)
Abstract A critical step to evaluate the potential in vivo antiviral activity of a drug is to connect the in vivo exposure to its in vitro antiviral activity. The Anti–SARS‐CoV‐2 Repurposing Drug Database is a database that includes both in vit
Externí odkaz:
https://doaj.org/article/0cb77c809c824b32835bc7a4a70613b8
Autor:
Xiaohui, Wei, Shabnam, Naseer, Edward A, Weinstein, Dmitri, Iarikov, Sumathi, Nambiar, Kellie S, Reynolds, Seong H, Jang
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:1004-1007
In this report, we describe our scientific approach for including effluent flow rate (Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b44f8444bfb9f5001a36a16617773b8
https://doi.org/10.1002/cpt.2703
https://doi.org/10.1002/cpt.2703
Publikováno v:
The Journal of Clinical Pharmacology. 62:1501-1506
Comprehensive characterization of transporter mediated drug-drug interactions (DDIs) is important to formulate clinical management strategies and ensure the safe and effective use of concomitantly administered drugs. The potential of a drug to inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7961f1387b80615744c4262c4c3f3702
https://doi.org/10.1002/jcph.2119
https://doi.org/10.1002/jcph.2119
Autor:
Vikram Arya, Xinyuan Zhang, Justin C. Earp, Kellie S. Reynolds, Yaning Wang, Manuela Grimstein, Hao Zhu, Yuching Yang, Eliford Kitabi, Jianghong Fan
Publikováno v:
Clinical Pharmacology & Therapeutics. 111:624-634
Remdesivir (RDV) is the first drug approved by the US Food and Drug Administration (FDA) for the treatment of coronavirus disease 2019 (COVID-19) in certain patients requiring hospitalization. As a nucleoside analogue prodrug, RDV undergoes intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbff2b27a48eab542615954b8b8f186
https://doi.org/10.1002/cpt.2445
https://doi.org/10.1002/cpt.2445
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:2884-2889
Background An antibacterial drug’s susceptibility test interpretive criteria (STIC) are determined by integrating clinical, microbiological and pharmacokinetic-pharmacodynamic (PK-PD) data. PTA analysis plays a pivotal or supportive role in STIC de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c478a50bdaff7985489793b6f3dac5c4
https://doi.org/10.1093/jac/dkab282
https://doi.org/10.1093/jac/dkab282
Autor:
Justin C. Earp, Eliford Kitabi, Dakshina Chilukuri, Timothy J Bensman, Elizabeth O’Shaughnessy, Leslie Ball, Philip M Colangelo, Yuliya Yasinskaya, Kellie S. Reynolds, Heidi Smith
Publikováno v:
Clinical Infectious Diseases. 73:903-906
For treatment of severe malaria, the World Health Organization recommends 3 mg/kg intravenous artesunate in pediatric patients weighing less than 20 kg. Here we describe the Food and Drug Administration’s rationale for selecting 2.4 mg/kg in pediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f18c46a84618e71c9937cae2bc0065
https://doi.org/10.1093/cid/ciab149
https://doi.org/10.1093/cid/ciab149
Autor:
Gillian Taormina, Kellie S. Reynolds, Ramya Gopinath, Yuliya Yasinskaya, Sumati Nambiar, Philip Colangelo, Jason N. Moore
Publikováno v:
Clinical Infectious Diseases. 73:2335-2340
Pathogenesis of neonatal candidiasis (NC) is distinct from systemic candidiasis in adults and older pediatric patients due to the significant incidence of central nervous system involvement in neonates. Thus, although adequate and well-controlled tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a458ca9e3bb58750cc2989f2a1432f8d
https://doi.org/10.1093/cid/ciab025
https://doi.org/10.1093/cid/ciab025
Autor:
Kellie S. Reynolds, Yaning Wang, Jeffry Florian, Seong H. Jang, Yichao Yu, Xiaohui Wei, Luning Zhuang
Publikováno v:
The Journal of Clinical Pharmacology. 60:1011-1021
The objectives of this study were to evaluate the effect of hemodialysis (HD) on the pharmacokinetics (PK) of meropenem/vaborbactam, an approved beta-lactam/beta-lactamase inhibitor combination, and provide the rationale for the recommended timing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c698bccdb06faca7fe3d7338617d965
https://doi.org/10.1002/jcph.1595
https://doi.org/10.1002/jcph.1595
Publikováno v:
Antimicrob Agents Chemother
In 2018, the FDA approved plazomicin for the treatment of complicated urinary tract infections (cUTI) including pyelonephritis in adult patients with limited or no alternative treatment options. The objective of this article is to provide the scienti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2d07787ab51cb43b6e8aae9fc43f46
https://europepmc.org/articles/PMC9017347/
https://europepmc.org/articles/PMC9017347/
Autor:
Eliford Kitabi, Timothy J Bensman, Justin C Earp, Dakshina M Chilukuri, Heidi Smith, Leslie Ball, Elizabeth O’Shaughnessy, Yuliya Yasinskaya, Kellie S Reynolds
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08828091321ecca1fa4f4ef8d67ef9cb
https://pubmed.ncbi.nlm.nih.gov/35023549
https://pubmed.ncbi.nlm.nih.gov/35023549