Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kellie Pickell"'
Autor:
Scott J Dylla, Lucia Beviglia, In-Kyung Park, Cecile Chartier, Janak Raval, Lucy Ngan, Kellie Pickell, Jorge Aguilar, Sasha Lazetic, Stephanie Smith-Berdan, Michael F Clarke, Tim Hoey, John Lewicki, Austin L Gurney
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2428 (2008)
Patients generally die of cancer after the failure of current therapies to eliminate residual disease. A subpopulation of tumor cells, termed cancer stem cells (CSC), appears uniquely able to fuel the growth of phenotypically and histologically diver
Externí odkaz:
https://doaj.org/article/ce101979cce848ca91bf3f680f3644ff
Autor:
Scott J. Dylla, Lucia Beviglia, In-Kyung Park, Cecile Chartier, Janak Raval, Lucy Ngan, Kellie Pickell, Jorge Aguilar, Sasha Lazetic, Stephanie Smith-Berdan, Michael F. Clarke, Tim Hoey, John Lewicki, Austin L. Gurney
Publikováno v:
PLoS ONE, Vol 3, Iss 8 (2008)
Externí odkaz:
https://doaj.org/article/11533853fa174d67801558262b738174
Autor:
Kellie Pickell, Andrew Lam, Lucas Donigan, Marcus Fischer, Satyajit Sujit Kumar Mitra, Fumiko Takada Axelrod, Hoang Tran, Aurélie Chaudhari, In-Kyung Park, Christopher J. Bond, Austin L. Gurney, Timothy Hoey, Sanjeev Satyal, Aaron K. Sato, John Lewicki, Jennifer Cain, Cecile Chartier, Michelle Stroud, Sasha Lazetic, Ann M. Kapoun, May Ji, Wan-Ching Yen, Shirley Ma
Publikováno v:
Proceedings of the National Academy of Sciences. 109:11717-11722
The Wnt/β-catenin pathway, which signals through the Frizzled (Fzd) receptor family and several coreceptors, has long been implicated in cancer. Here we demonstrate a therapeutic approach to targeting the Wnt pathway with a monoclonal antibody, OMP-
Autor:
Cristina Dee-Hoskins, Kellie Pickell, Jakob Dupont, Roger Lopez, Gilbert O'Young, Min Wang, Austin L. Gurney, Tim Hoey, Raymond Tam, Ann M. Kapoun, Alayne Brunner, James P. Evans, Belinda Cancilla, John Lewicki, Wan-Cheng Yen, Xiaomei Song, Angie Inkyung Park, Chun Zhang, Lei Zhou, Marcus Fischer
Publikováno v:
Clinical Cancer Research. 22:A42-A42
OncoMed Pharmaceuticals is focused on discovering novel therapies that target cancer stem cells (CSCs), specifically those which depend on the Notch or Wnt pathways. Since Patient Derived Xenografts (PDXs) recapitulate both tumor cell heterogeneity a
Autor:
John Lewicki, Austin L. Gurney, Tim Hoey, Lucy Ngan, Lucia Beviglia, Scott J. Dylla, Kellie Pickell, Jorge Aguilar, In-Kyung Park, Mike Clarke, Sasha Lazetic, Cecile Chartier, Janak Raval, Stephanie Smith-Berdan
Publikováno v:
PLoS ONE, Vol 3, Iss 8 (2008)
PLoS ONE
PLoS ONE
In the Materials and Methods section, in the fifth line below the "In Vitro Culture & Cytotoxicity Studies" heading, the correct final concentration of LIF used in this study was 1 x 10e3 u/mL.