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pro vyhledávání: '"Kellie Nader"'
Autor:
Kellie Nader, David L. Ennist, Gary Kikuchi, Chris Lockey, Tracey Grooms, Stephen N. Mueller, Stephen G. Marcus, Irina Burimski, Zhifeng Long, Patricia Ryan, Lie-Ping Li, Gerard J. McGarrity, Edward Otto, Ihor Mychkovsky
Publikováno v:
Human gene therapy. 9(8)
Patients with recurrent malignant brain cancer, who were receiving gene therapy by intracerebral injection of murine retroviral vector producer cells (VPCs), were monitored for the presence of replication-competent retrovirus (RCR). RCR sequences wer
Publikováno v:
Human gene therapy. 7(9)
Replication-deficient amphotropic retrovirus vectors (RV) or RV-producer cells are being developed for a variety of human gene therapy strategies. One of the hurdles to in vivo use of these agents is their inactivation by components of human serum. M